Review of Child sexual abuse: Critical perspectives on prevention, intervention, and treatment.

Reviews the book, Child sexual abuse: Critical perspectives on prevention, intervention, and treatment edited by Christopher R. Bagley and Ray J. Thomlison (1991). This book is a compilation of a series of literature reviews originally commissioned by Health and Welfare Canada in 1987 and completed in 1988. The individual papers included in this edited version represent a cross section of Canadian academicians, clinicians, and case workers who are integrally involved in the policies and practices regarding child sexual abuse in Canada. The work provides a comprehensive perspective on prevention at the primary, secondary, and tertiary levels. The list of authors is impressive in terms of their expertise and experience. At a time when numerous books on child sexual abuse are appearing on the market, it is nice to see a book that has some unusual aspects. Aside from its distinctly Canadian perspective, the book addresses several important, yet frequently ignored, topics. The book provides an up-to-date review of several core issues: conceptualization of the problem, prevention strategies, impact of sexual abuse, investigative interviewing, treatment outcome studies, and treatment issues for child molesters. The more unique topics include a review of the strategies used to evaluate prevention programs, prevalence rates among a number of special populations, the role of medical practitioners in preventing and intervening in child sexual abuse, and sexual abuse and exploitation among disabled individuals. Overall, I can recommend this book for clinicians and researchers in Canada and elsewhere who are interested in child sexual abuse. This compilation of literature reviews highlights the leading role that Canadian social service agencies have taken in developing programs for sexually abused children and their families. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Identifying Candidate Protein Markers of Acute Kidney Injury in Acute Decompensated Heart Failure

One-quarter of patients with acute decompensated heart failure (ADHF) experience acute kidney injury (AKI)—an abrupt reduction or loss of kidney function associated with increased long-term mortality. There is a critical need to identify early and real-time markers of AKI in ADHF; however, to date, no protein biomarkers have exhibited sufficient diagnostic or prognostic performance for widespread clinical uptake. We aimed to identify novel protein biomarkers of AKI associated with ADHF by quantifying changes in protein abundance in the kidneys that occur during ADHF development and recovery in an ovine model. Relative quantitative protein profiling was performed using sequential window acquisition of all theoretical fragment ion spectra–mass spectrometry (SWATH–MS) in kidney cortices from control sheep (n = 5), sheep with established rapid-pacing-induced ADHF (n = 8), and sheep after ~4 weeks recovery from ADHF (n = 7). Of the 790 proteins quantified, we identified 17 candidate kidney injury markers in ADHF, 1 potential kidney marker of ADHF recovery, and 2 potential markers of long-term renal impairment (differential abundance between groups of 1.2–2.6-fold, adjusted p < 0.05). Among these 20 candidate protein markers of kidney injury were 6 candidates supported by existing evidence and 14 novel candidates not previously implicated in AKI. Proteins of differential abundance were enriched in pro-inflammatory signalling pathways: glycoprotein VI (activated during ADHF development; adjusted p < 0.01) and acute phase response (repressed during recovery from ADHF; adjusted p < 0.01). New biomarkers for the early detection of AKI in ADHF may help us to evaluate effective treatment strategies to prevent mortality and improve outcomes for patients.     

重新设计重新填充:设计指南

本文为设计可持续性、可再充填料的设计团队提供了指导方针。该研究集中在个人护理领域的"沐浴露"产品。广泛的定性方法用于创建背景框架,开发设计概念,而且测试设计方案的可行性。将两个概念转化为高精确度原型,和在多活动用户焦点组中进行测试。使用Eco-indicator 99的环境角度对原型进行了评估。讨论的重点是关于可再填充的包装的一般发现,和与"浓缩混合在母体包中"相关的具体发现。"这项研究的发现极大地提高了人们对可再填充包装的潜在影响的理解水平,和它如何被商业成功应用。"已经确定了一系列的重新填充物设计的指导方针,这有助于更清晰地了解可再填充包装设计的要求。此外,更详细的了解最新的消费者认知情况,相关业务挑战和机遇,节约和环境"集中补充,混合在父包,"已被确认。人们已经看到,要想成功地重新填充,必须为消费者、环境和企业执行,尽管这听起来并不令人惊讶,但实现起来很有挑战性。这意味着他们必须提供良好的质量;非常容易使用和适当的交付;被清楚地沟通;通过品牌消费者提供;而且代表了良好的价值,同时从根本上减少了制造和分发包装的数量。将仔细考虑的消费者和环境需求结合在一起,对可再填充包装的成功开发至关重要。     

Validation chez les adolescents d'une version francophone d'un instrument de mesure de la peur du jugement négatif d'autrui.

The popularity of the Fear of Negative Evaluation scale (FNE; Watson & Friend, 1969) stems from the centrality of this construct in personality, social and clinical psychology. In order to meet the needs of the Francophone researchers community, Kéroack, Boisvert, and Prévost (1987) traduced the short version of this instrument. Since social anxiety is most salient in adolescence, there is a need for normative and psychometric data for this population. This research aims at documenting the psychometric properties and norms for Francophone adolescents. Five hundred and seventy-eight participants aged from 14 to 19 years completed the French versions of the short FNE and the Social Avoidance and Distress scale. The factorial structure, the internal consistency and the convergent validity analyses confirm the traduction's quality and the questionnaire's validity. Norms are presented separately for females and males. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Imagined empathy and attributions concerning activity preferences of physically disabled college students.

Investigated 89 college students' attributions about the activity preferences of able-bodied vs physically disabled peers and evaluated the effects of imagined empathy on attributional patterns and attitudes toward disabled people. Ss were asked to predict the responses of either a male or a female able-bodied or wheelchair-user college student to items on a 20-item questionnaire offering choices between gregarious–nongregarious activities and between active–passive activities. Results indicate that there was considerable variability in able-bodied students' attributions about disabled peers' activity preferences. Previous contact with disabled people was unrelated either to attitudes toward disabled people or to activity preference attributions. Asking students to imagine empathy for a disabled peer was not an effective technique to change either attributional patterns or attitudes toward disabled people. (16 ref) (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Resonance and nonresonant laser ionization of sputtered uranium atoms from thin films and single microparticles: evaluation of a combined system for particle trace analysis

The resonance and nonresonant laser ionization of uranium atoms sputtered from thin metal films and individual micrometer-size uranium oxide particles, respectively, was studied to evaluate a new setup for the analysis of actinide-containing micrometer-size particles. Experiments using nonresonant (193-nm) ionization of atoms and molecules sputtered from micrometer-size uranium oxide particles have shown that the uranium detection efficiencies for sputtered neutral atoms are approximately 2 orders of magnitude higher than for secondary ions. In uranium particles of 0.5-microm diameter, 6 x 10(6) atoms of 235U were easily detected and the isotopic ratio of 235U/238U = 0.0048 +/- 4.6% is in excellent agreement with the certified value. The use of two-color, two-step resonance ionization of the sputtered neutral uranium atoms from thin films was investigated. Several excitation schemes were tested, and a significant population of several low-lying metastable states after ion sputtering was observed. Autoionizing states for double-resonant ionization were determined, and the high selectivity of ionization schemes involving these autoionizing states was illustrated by comparing the flight-time distributions of different sputtered species obtained both by resonance and nonresonant multiphoton (355-nm) laser postionization. Ideally, the options for resonance as well as nonresonant ionization would be combined in a single setup, to obtain a large gain in sensitivity and selectivity. Thus, information about the main components as well as specific isotopic information of a trace element could be obtained from the same single particle.     

Polyhedral studies for minimum-span graph labelling with integer distance constraints

This paper studies the polytope of the minimum‐span graph labelling problems with integer distance constraints (DC‐MSGL). We first introduce a few classes of new valid inequalities for the DC‐MSGL defined on general graphs and briefly discuss the separation problems of some of these inequalities. These are the initial steps of a branch‐and‐cut algorithm for solving the DC‐MSGL. Following that, we present our polyhedral results on the dimension of the DC‐MSGL polytope, and that some of the inequalities are facet defining, under reasonable conditions, for the polytope of the DC‐MSGL on triangular graphs.