FDTD simulation of 30 /spl mu/m diameter polymer micro-ring

Numerical results on polymer surrounded by an air micro-ring coupled to waveguides are presented. The FDTD method predicts a filter width of 1.4 nm and an extraction efficiency of almost 80% for a gap of 0.15 /spl mu/m.     

Design of statistical databases: A methodology for the conceptual step

The aim of the conceptual step in database design is to describe data involving in the application in a formal and abstract way, without any concern to the specific model and language chosen for the implementation. In statistical applications, data are described at different levels of aggregation, from elementary facts of the reality to complex aggregations such as classifications, time series, indexes. The paper describes a methodology for conceptual design of statistical databases that provides the designer suitable strategies for defining such different levels of aggregation starting from user requirements, and checking the completeness, coherence and minimality of the conceptual schema at the different levels. The methodology makes use of two data models for the representation of data: for elementary data the Entity-Relationship model, widely used in database applications, and for summary data a new model is proposed, designed to be an effective trade-off between expressive power and simplicity of use.     

Functional polymers

Summary Polymeric antioxidants prepared from 2,6-di-tertiary-butyl-4-vinyl (4-lsopropenyl)phenol and butadiene or isoprene, and their hydrogenated products (6-8 mol % of phenolic AO in the polymer) were tested by oxygen uptake studies for their effectiveness as antioxidants for polyolefins and polydienes. The polymeric antioxidants seem to be slightly less effective in short-term protection against oxidation at 150° C as compared to low molecular weight antioxidants, but more effective in long-term protection of the polymer samples at a level of 0.1 weight percent.Part 43: P. Grosso, O. Vogl: J. Macromol. Sci. Chem., in pressNow Chemical Company, Midland, MI 48674, USATo whom all correspondence should be addressed: Herman F. Mark Professor of Polymer Science, Polytechnic Institute of New York, Brooklyn, NY 11201, USA     

Insights into the Action Mechanism of the Antimicrobial Peptide Lasioglossin III

Lasioglossin III (LL-III) is a cationic antimicrobial peptide derived from the venom of the eusocial bee Lasioglossum laticeps. LL-III is extremely toxic to both Gram-positive and Gram-negative bacteria, and it exhibits antifungal as well as antitumor activity. Moreover, it shows low hemolytic activity, and it has almost no toxic effects on eukaryotic cells. However, the molecular basis of the LL-III mechanism of action is still unclear. In this study, we characterized by means of calorimetric (DSC) and spectroscopic (CD, fluorescence) techniques its interaction with liposomes composed of a mixture of 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine (POPC) and 1-palmitoyl-2-oleoyl-sn-glycero-3-rac-phosphoglycerol (POPG) lipids as a model of the negatively charged membrane of pathogens. For comparison, the interaction of LL-III with the uncharged POPC liposomes was also studied. Our data showed that LL-III preferentially interacted with anionic lipids in the POPC/POPG liposomes and induces the formation of lipid domains. Furthermore, the leakage experiments showed that the peptide could permeabilize the membrane. Interestingly, our DSC results showed that the peptide-membrane interaction occurs in a non-disruptive manner, indicating an intracellular targeting mode of action for this peptide. Consistent with this hypothesis, our gel-retardation assay experiments showed that LL-III could interact with plasmid DNA, suggesting a possible intracellular target.     

Visual discovery of the correlation between BGP routing and round-trip delay active measurements

Inter-domain routing data and Internet active probing measurements are two types of information commonly available in huge datasets and subject to extensive, focused analysis. However, the study of the correlation between these two complementary types of information still remains one of the most challenging problems in today’s research in networking. In this paper we describe a metaphor for the visualization of the interplay between the routing information exchanged via BGP and the round-trip delay measurements collected by several geolocated probes. We implemented a prototype based on the above metaphor. Our prototype highlights both the Autonomous System topology and the latency associated with each AS-path over time. Further, it shows how probes are partitioned into clusters associated with each border gateway, based on observed traffic patterns. The resulting visualization allows the user to explore the dynamics of the correlation between the two types of information.     

Note: Simultaneous electrical and optical detection of expanding dense partially ionized vapour clouds

The scheme and construction of an electro-optical probe able to collect charge and detect optical emission from expanding dense partially ionized vapour clouds are reported. The instrument can be applied to phenomena such as dust impact ionization and solid target laser ablation. First, results of measurements of expanding plasma cloud formed upon ablating W target are presented. Use of the instrument in different experimental facilities, including tokamak, is discussed.     

Quasi-Upward Planarity

Abstract. An upward planar drawing of a directed graph (digraph) is a planar drawing such that all the edges are represented by curves monotonically increasing in the vertical direction. In this paper we introduce and study the concept of quasi-upward planarity. Quasi-upward planarity allows us to extend the upward planarity theory to a large class of digraphs including digraphs that also have directed cycles. First, we characterize the digraphs that have a quasi-upward planar drawing. Second, we give a polynomial time algorithm for computing ``optimal' quasi-upward planar drawings within a given planar embedding. Further, we apply branch and bound techniques to the problem of computing optimal quasi-upward planar drawings, considering all possible planar embeddings. The paper also contains experimental results about the proposed techniques.