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M. Mbonimpa M. Aubertin A. Maqsoud B. Bussière 《Canadian Metallurgical Quarterly》2006,132(9):1121-1132
Tests for determining the water retention curve (WRC) can be time-consuming and tedious, especially with deformable soils for which volume change and water content have to be simultaneously monitored. In some cases, predictive models can become a practical alternative to obtain an estimate of the WRC. However, very few models are available to predict the WRC of deformable materials under increasing suction. In this paper, the modified Kovács (MK) model, developed initially for incompressible soils, is extended to describe and, in some cases, predict the WRC of deformable clayey soils. This generalization of the MK model is performed by introducing the volumetric shrinkage curve (VSC) in its formulation. A curvilinear equation is proposed to represent the void ratio-suction function e(ψ) corresponding to the VSC. This VSC model and the extended MK model (MKd) are validated using experimental data taken from the literature. Empirical relationships are developed for predictive purposes to estimate the parameters involved, using basic geotechnical properties. Applications show a good agreement between measured and calculated WRC. 相似文献
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Access to safe, reliable sources of drinking water is a long-standing problem among people in developing countries. Sustainable solutions to these problems often involve point-of-use or community-scale water treatment systems that rely on locally-available resources and expertise. This philosophy was used in the development of a continuous-flow, solar UVB disinfection system. Numerical modeling of solar UVB spectral irradiance was used to define temporal variations in spectral irradiance at several geographically-distinct locations. The results of these simulations indicated that a solar UVB system would benefit from incorporation of a device to amplify ambient UVB fluence rate. A compound parabolic collector (CPC) was selected for this purpose. Design of the CPC was based on numerical simulations that accounted for the shape of the collector and reflectance. Based on these simulations, a prototype CPC was constructed using materials that would be available and inexpensive in many developing countries. A UVB-transparent pipe was positioned in the focal area of the CPC; water was pumped through the pipe to allow exposure of waterborne microbes to germicidal solar UVB radiation. The system was demonstrated to be effective for inactivation of Escherichia coli, and DNA-weighted UV dose was shown to govern reactor performance. The design of the reactor is expected to scale linearly, and improvements in process performance (relative to results from the prototype) can be expected by use of larger CPC geometry, inclusion of better reflective materials, and application in areas with greater ambient solar UV spectral irradiance than the location of the prototype tests. The system is expected to have application for water treatment among communities in (developing) countries in near-equatorial and tropical locations. It may also have application for disaster relief or military field operations, as well as in water treatment in areas of developed countries that receive relatively intense solar UVB radiation. 相似文献
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Ella Larissa Ndoricyimpaye Jacques Van Snick Jean de Dieu Niyoyita Philbert Kanimba Jean Bosco Mbonimpa Robert Rutayisire Rverien Rutayisire Vedaste Ndahindwa Pamla Cheou Jean Paul Coutelier Nadine Rujeni 《International journal of molecular sciences》2022,23(20)
The proper control of Plasmodium infection requires a finely balanced immune response. Here, we evaluated the implication of TGF-β1 and TGF-β3 in this process using novel monoclonal antibodies to measure their plasma concentrations in comparison with other cytokines and the expression of FOXP3 mRNA. Plasma cytokine levels were measured in 80 patients with severe anaemic malaria and 186 with a mild presentation using ELISA, and rtPCR was used to measure FOXP3 mRNA expression. While no mature TGF-β isoforms were detected in the plasma, the latent TGF-β1 and TGF-β3 were strongly upregulated in patients with mild malaria and nearly undetected in patients with severe disease. Similar selective upregulation in mild patients was observed for IL-9 and FOXP3 mRNA, while IL-7, IL-10, IL-17, and IL-27, although higher in mild cases, were also detected in severe disease. In contrast, a clearly skewed trend of severe cases towards higher pro-inflammatory (IL-6, IL-13, TNF-α) and Th1 (IFN-γ) responses was observed, which was associated with a higher level of parasitaemia as well as lower IgG and higher IgM responses. Together, these results suggest that the stimulation of regulatory T cells through TGF-β1/TGF-β3 and IL-9 is paramount to an effective and balanced protective immunity in natural human malaria infection. 相似文献
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Robert P. Chapuis Mamert Mbonimpa Anne-Marie Dagenais Michel Aubertin 《Bulletin of Engineering Geology and the Environment》2006,65(1):93-98
It is proposed to present compaction relationships by plotting the inverse of the dry density versus the molding water content. In the proposed graph, the curves for equal degree of saturation become straight lines. The proposed new graph is shown to be very convenient to assess the saturated hydraulic conductivity, k
sat, of non-swelling compacted clay, using a dual porosity model. The value of k
sat depends on the secondary porosity between clay clods. The equation developed for equal k
sat value appears also as a straight line in the proposed graph. It facilitates the prediction of k
sat from field compaction data and thus the prediction of field performance of clay liners and covers. 相似文献
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Field Study of the Chemical and Physical Stability of Highly Sulphide-Rich Tailings Stored Under a Shallow Water Cover 总被引:1,自引:0,他引:1
Highly sulfide-rich (approximately 83 % pyrite), potentially acid-generating mine tailings were sub-aqueously deposited in the Don Rouyn old quarry pit from 1997 to 2000. The site covers approximately 7 ha near Rouyn-Noranda, Quebec. Various in situ measurements and laboratory tests were performed during the summer and autumn of 2008, 2009, and 2010 to: characterize tailings samples; monitor water quality in the final effluent, shallow water cover, and groundwater around the pit, and; study tailings erosion and resuspension. In situ measurements included the vertical profile and spatial distribution of pH, temperature, dissolved oxygen, electric conductivity, and redox potential. Suspended tailings, wind speed, and direction were monitored. Groundwater, cover water, and final effluent water samples were chemically analyzed and suspended sediment concentrations (SSCs) was determined. Physical, mineralogical, and chemical tailings properties were also determined. Results show that the quality of the groundwater, cover, and effluent waters complied with Canadian and Quebec regulations. SSCs were also within regulation limits. No association was found between SSC and hydrodynamic conditions (wind speed, fetch, etc.). Although theoretical calculations indicated a critical wind speed of at least 10 m/s for tailings resuspension, suspended sediment was observed for wind speeds at <10 m/s. 相似文献
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