This paper presents a case study of an optimized combination of mine water control, treatment, utilization and reinjection to achieve the zero discharge of mine water. Mine water has been considered a hazard and pollution source during underground mining, so most mining enterprises directly discharge mine water to the surface after simple treatment, resulting in a serious waste of water. Moreover, discharging a large amount of mine water can destroy the original groundwater balance and cause serious environmental problems, such as surface subsidence, water resource reduction and contamination, and adverse impacts on biodiversity. The Zhongguan iron mine is in the major groundwater source area of the Hundred Springs of Xingtai, which is an area with a high risk of potential subsidence. To optimize the balance between mining and groundwater resources, a series of engineering measures was adopted by the Zhongguan iron mine to realize mine water control, treatment, utilization, and reinjection. The installation of a closed grout curtain has greatly reduced the water yield of deep stopes in the mine; the effective sealing efficiency reaches 80%. Nanofiltration membrane separation was adopted to treat the highly mineralized mine water; the quality of the produced water meets China’s recommended class II groundwater standard. Low-grade heat energy from the mine water is collected and utilized through a water-source heat pump system. Finally, zero mine water discharge is realized through mine water reinjection. This research provides a beneficial reference for mines with similar geological and hydrogeological conditions to achieve environmentally sustainable mining.
As one of the most effective location privacy preservation technologies, the k-anonymity model provides safeguards for location privacy of the mobile client against vulnerabilities for abuse by constructing an anonymous area of k users including the protected one. However, most existing k-anonymity models only utilize the users who are sending requests at recent time. If there are not enough requesting users, the generated anonymous area of the k-anonymity model will be larger than expected. In this paper, a Probability-based Location Anonymity (PLA) algorithm is proposed for protecting location privacy of the mobile users in a road network. The PLA model takes advantage of the historical path track of the users who are not sending the request currently, and then computes the probability into the anonymous section so that it can greatly reduce the size of the anonymous area. Experimental results show that the PLA algorithm is superior to the k-anonymity and it increases its anonymous efficiency enormously. 相似文献
Diseases caused by systemic fungal infections have become a significant clinical problem in recent decades. A series of glycosyl derivatives of the approved cyclic peptide antifungal drug caspofungin conjugated with β‐D ‐glucopyranose, β‐D ‐galactopyranose, β‐D ‐xylopyranose, β‐L ‐rhamnopyranose, β‐maltose and β‐lactose units were designed, synthesized, and evaluated as new potential antifungal drugs. The compounds were obtained by coupling the corresponding glycosyl amines to the free primary amino groups of caspofungin through a bifunctional glutaryl linker. In contrast to caspofungin, these glycosylated derivatives are soluble in water, but are not hygroscopic and moreover, are more stable than caspofungin under high humidity and temperature. CD studies showed that glycosylation has very little impact on the conformation of the cyclic peptide of caspofungin. In vitro antifungal tests against seven human pathogenic fungi revealed that the caspofungin–monosaccharide conjugates, but not the disaccharide conjugates, have increased antifungal activities against the majority of tested fungus species relative to caspofungin. The β‐D ‐glucopyranosyl derivative 2 a showed the strongest and broadest antifungal activity, providing a lead for further studies. 相似文献
