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A mathematical model of working memory is proposed in the form of a network of neuron-like units interacting via global inhibitory feedback. This network is capable of storing information items in the form of clusters of periodical spiking activity. Several sequentially excited clusters can coexist simultaneously, corresponding to several items stored in the memory. The capacity of the memory is studied as the function of the system parameters. 相似文献
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Javier-Reyna R Hernández-Ramírez VI González-Robles A Galván-Mendoza I Osorio-Trujillo C Talamás-Rohana P 《Microscopy research and technique》2012,75(3):285-293
In vitro interaction of Entamoeba histolytica trophozoites with fibronectin (FN) induces redistribution of the amoebic fibronectin receptor (β1EhFNR). Trafficking of beta1 integrins is important for cell adhesion and migration in higher eukaryotes and requires the participation of Rab proteins. In E. histolytica, the machinery involved in integrin trafficking is not completely known. EhRab7 is a 24.5-kDa protein whose alignment with other Rab7 proteins demonstrated that it shared significant homology with Rab7 proteins from other organisms, including humans. Using different types of microscopy (fluorescence and confocal microscopy), it was established that Rab7 and the actin cytoskeleton participated in the mobilization of β1EhFNR in FN-stimulated trophozoites. β1EhFNR and Rab7 co-localized only in vesicular structures at 5 min, and at longer time (1 h), both co-localized in both plasma membrane and in vesicular structures; at the same time, Rab7 co-localized with specific actin structures (phagocytic vacuoles). At 5 h the β1EhFNR, Rab7, and actin co-localized at the plasma membrane, and only β1EhFNR and Rab7 decorated vesicles of different sizes. Actin and Rab7 co-localized in a cap-like structure at one end of the cell. Fluorescence resonance energy transfer and electron microscopy confirmed the close interaction between β1EhFNR and Rab7. Moreover, the use of a lysosome-specific marker (LysoTracker) and a Golgi-specific marker (NBD C(6)-ceramide) allowed us to establish that, at some point within the endocytic route, β1EhFNR and Rab7 co-localized within a lysosome-type organelle, but not a Golgi-like organelle, which indicated that this integrin-like molecule was returned to the plasma membrane via exocytic or secretory vesicles. 相似文献
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氰化浸出渣中有价金属的综合回收研究 总被引:1,自引:0,他引:1
通过对浮选精矿氰化浸出渣的综合回收研究,得出了有效利用氰化浸出渣中的有价金属的方法,即经过再磨再选,可以使其中的Cu、S、Au、Ag等有价金属得到有效回收,寒一步增加了企业经济效益。 相似文献
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充气调浆是硫化矿物浮选的重要影响因素。生产实践中通过时铜、锌、硫浮选前充气调浆,大大改善了浮选指标,在原矿品位波动较大的情况下,同名精矿中铜、锌、硫的回收率分别提高6.43%、0.17%和16.52%,充分说明充气调浆能选择性地活化和抑制不同种类的硫化矿物。 相似文献
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自磨和半自磨技术的研究进展 总被引:3,自引:1,他引:3
本文介绍了一项关于自磨和半自磨的革新技术。该技术将用于矿石和建筑材料的细磨生产方面。可应用于自磨、半自磨和球磨中的悬臂型磨机设计,具有运转能耗低,运输和安装简易等优点。报导了一种新型的踵形衬板的试验结果。试验由TTD公司、ALROSA公司、MINTEK研究所和英美公司研究实验室合作完成。该技术还包含一项新型格子板设计和一项处理临界粒度物料的技术。这些革新使得自磨机和半自磨机的磨矿效果进一步提高,生产能力提高1.5倍,电耗降低1/3—1/2。 相似文献
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We studied in dynamics 72 babies with cerebral perinatal disturbances aged up to 3 months (32 boys and 40 girls) in City Maternity Homes No 1 and No 4 and in New-Born Pathology Department of City Infant Hospital No 1 in Krasnoyarsk. All babies were divided into four groups according to the character and schedule of feeding: I-st group--babies, fed with mammary milk at the first 2 hours and being fed more than 10 times during the day with obligatory night feeding; II-nd group--babies, fed with mammary milk at the first 2 hours and being fed 6 times during the day usually with night break; III-rd group--babies, fed with mammary milk in 6-8 hours after birth and being fed more than 10 times during the day with obligatory night feeding; IV-th group--babies, fed with mammary milk in 6-8 hours after birth and being fed 6 times during the day with usual night break. We have marked faster tempo of normalization in indices of neurological status and physical development in groups of infants, fed with mammary milk at the first 2 hours and being fed more that 10 times during a day with obligatory night feeding as compared to babies, which were fed according to common schedule. We didn't find the dependence from the stage of perinatal pathology of nerve system. Frequency of functional disturbances in cardio rhythm, malfunctions of gastrointestinal tract, allergy diseases and iron-deficiency anemia in babies, fed with special food in early age (not mammary milk) is evidently higher as compared to babies, fed with mammary milk only. We received the results of examination in dynamics which prove, that mammary milk creates favorable background for the development of adaptation processes in baby organism, which allows faster compensation of residual factors, connected with perinatal disturbances of nerve system. 相似文献