Microstructural transformations of heat affected zones in duplex steel welded joints

The influence of the welding thermal conditions exemplified by heat input and heat treatment after welding on the structure of the heat affected zone (HAZ) UNS S31803 has been analysed. The post weld treatment was used to create the precisely defined thermal conditions for the decomposition of primary phases in the HAZ, by a multi-layer welding thermal cycle stimulation. Detailed analyses of the microstructure and chemical composition of the phases in the different post welded conditions were performed by scanning electron microscopy (SEM) combined with energy dispersive spectrometry (EDS) and transmission electron microscopy (TEM). Three types of secondary precipitates have been observed: secondary austenite (γ₂), carbides: M₂₃C₆ and M₇C₃. The dependence of the secondary austenite volume fraction and morphology in the HAZ on thermal cycle have been interpreted. The eutectoid decomposition of the primary phases in the analysed thermal conditions was confirmed.     

Fast Recognition of Fibonacci Cubes

Fibonacci cubes are induced subgraphs of hypercubes based on Fibonacci strings. They were introduced to represent interconnection networks as an alternative to the hypercube networks. We derive a characterization of Fibonacci cubes founded on the concept of resonance graphs. The characterization is the basis for an algorithm which recognizes these graphs in O(mlog n) time. A. Vesel supported by the Ministry of Science of Slovenia under the grant 0101-P-297.     

Characterization of Urine Stem Cell-Derived Extracellular Vesicles Reveals B Cell Stimulating Cargo

Elucidation of the biological functions of extracellular vesicles (EVs) and their potential roles in physiological and pathological processes is an expanding field of research. In this study, we characterized USC–derived EVs and studied their capacity to modulate the human immune response in vitro. We found that the USC–derived EVs are a heterogeneous population, ranging in size from that of micro–vesicles (150 nm–1 μm) down to that of exosomes (60–150 nm). Regarding their immunomodulatory functions, we found that upon isolation, the EVs (60–150 nm) induced B cell proliferation and IgM antibody secretion. Analysis of the EV contents unexpectedly revealed the presence of BAFF, APRIL, IL–6, and CD40L, all known to play a central role in B cell stimulation, differentiation, and humoral immunity. In regard to their effect on T cell functions, they resembled the function of mesenchymal stem cell (MSC)–derived EVs previously described, suppressing T cell response to activation. The finding that USC–derived EVs transport a potent bioactive cargo opens the door to a novel therapeutic avenue for boosting B cell responses in immunodeficiency or cancer.     

Jumps and logic in the law

The main stream of legal theory tends to incorporate unwritten principles into the law. Weighing of principles plays a great role in legal argumentation, inter alia in statutory interpretation. A weighing and balancing of principles and other prima facie reasons is a jump. The inference is not conclusive.To deal with defeasibility and weighing, a jurist needs both the belief-revision logic and the nonmonotonic logic. The systems of nonmonotonic logic included in the present volume provide logical tools enabling one to speak precisely about various kinds of rules about rules, dealing with such things as applicability of rules, what is assumed by rules, priority between rules and the burden of proof. Nonmonotonic logic is an example of an extension of the domain of logic. But the more far-reaching the extension is, the greater problems it meets. It seems impossible to make logical reconstruction of the totality of legal argumentation.The lawyers' search for reasons has no obvious end point. Ideally, the search for reasons may end when one arrives at a coherent totality of knowledge. In other words, coherence is the termination condition of reasoning. Both scientific knowledge and knowledge of legal and moral norms progresses by trial and error, and that one must resort to a certain convention to define what error means. The main difference is, however, that conventions of science are much more precise than those of legal scholarship.Consequently, determination of error in legal science is often holistic and circular. The reasons determining that a legal theory is erroneous are not more certain than the contested theory itself. A strict and formal logical analysis cannot give us the full grasp of legal rationality. A weaker logical theory, allowing for nonmonotonic steps, comes closer, at the expense of an inevitable loss of computational efficiency. Coherentist epistemology grasps even more of this rationality, at the expense of a loss of preciseness.     

A Review of Critical Plane Orientations in Multiaxial Fatigue Failure Criteria of Metallic Materials

The paper presents a review of multiaxial fatigue failure criteria based on the critical plane concept. The criteria have been divided into three groups, according to the fatigue damage parameter used in the criterion, i.e. (i) stress, (ii) strain and (iii) strain energy density criteria. Each criterion was described mainly by the critical plane orientation. Multiaxial fatigue criteria based on the critical plane concept usually apply different loading parameters in the critical plane whose orientation is determined by (a) only shear loading parameters (crack Mode II or III), (b) only normal loading parameters (crack Mode I) or sometimes (c) mixed loading parameters (mixed crack Mode). There are also criteria based on few critical plane orientations and criteria based on critical plane orientations determined by a weighted averaging process of rotating principal stress axes.     

台阶地形上波浪运动的数值研究

波浪在水深剧变地形上的传播，可以简化为波浪在台阶地形上的传播.利用二维数值波浪水槽可以很好地模拟这一过程，特别是对波浪在台阶上的非线性变形.数值计算结果与实验测量进行了比较，结果吻合良好.     

Polycationic star polymers with hyperbranched cores for gene delivery

Core-shell type stars synthesized via atom transfer radical polymerization were used for the delivery of nucleic acids. The interior of the stars consisted of hyperbranched poly(arylene oxindole), while the arms were composed of poly(N,N-dimethylaminoethyl methacrylate). The length of the star arms varied in degree of polymerization (DP) from 14 to 98. The hydrodynamic radius of the structures measured in water indicated the presence of small aggregates, while isolated stars ranging in size from 14 to 29 nm were seen in organic solvent. The phase transition temperatures of the stars in water, measured in basic conditions, were shifted to lower values with increasing DP of the arms. Stable polyplexes of stars with plasmid DNA were formed. Their size varied from 300 nm to 400 nm, depending upon the DP of arms. The zeta potential of the polyplexes was positive, which facilitated their cellular uptake. The DP of the arms influenced the transfection efficiency of HT-1080 cells, demonstrating that stars are promising candidates for synthetic gene vectors.