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排序方式: 共有1704条查询结果,搜索用时 31 毫秒
1.
2.
Shank S. Kulkarni Kyoo Sil Choi Wenbin Kuang Nalini Menon Bernice Mills Ayoub Soulami Kevin Simmons 《International Journal of Hydrogen Energy》2021,46(36):19001-19022
The use of hydrogen as a fuel is increasing exponentially, and the most economical way to store and transport hydrogen for fuel use is as a high-pressure gas. Polymers are widely used for hydrogen distribution and storage systems because they are chemically inert towards hydrogen. However, when exposed to high-pressure hydrogen, some hydrogen diffuses through polymers and occupies the preexisting cavities inside the material. Upon depressurization, the hydrogen trapped inside polymer cavities can cause blistering or cracking by expanding these cavities. A continuum mechanics–based deformation model was deployed to predict the stress distribution and damage propagation while the polymer undergoes depressurization after high-pressure hydrogen exposure. The effects of cavity size, cavity location, and pressure inside the cavity on damage initiation and evolution inside the polymer were studied. The stress and damage evolution in the presence of multiple cavities was also studied, because interaction among cavities alters the damage and stress field. It was found that all these factors significantly change the stress state in the polymer, resulting in different paths for damage propagation. The effect of adding carbon black filler particles and plasticizer on the damage was also studied. It was found that damage tolerance of the polymer increases drastically with the addition of carbon black fillers, but decreases with the addition of the plasticizer. 相似文献
3.
Dr. Alejandra A. Carriles Alberto Mills Dr. María-José Muñoz-Alonso Dr. Dolores Gutiérrez Dr. Juan M. Domínguez Prof. Dr. Juan A. Hermoso Prof. Dr. Federico Gago 《Chembiochem : a European journal of chemical biology》2021,22(2):374-391
Spontaneous mutations in the EEF1A2 gene cause epilepsy and severe neurological disabilities in children. The crystal structure of eEF1A2 protein purified from rabbit skeletal muscle reveals a post-translationally modified dimer that provides information about the sites of interaction with numerous binding partners, including itself, and maps these mutations onto the dimer and tetramer interfaces. The spatial locations of the side chain carboxylates of Glu301 and Glu374, to which phosphatidylethanolamine is uniquely attached via an amide bond, define the anchoring points of eEF1A2 to cellular membranes and interorganellar membrane contact sites. Additional bioinformatic and molecular modeling results provide novel structural insight into the demonstrated binding of eEF1A2 to SH3 domains, the common MAPK docking groove, filamentous actin, and phosphatidylinositol-4 kinase IIIβ. In this new light, the role of eEF1A2 as an ancient, multifaceted, and articulated G protein at the crossroads of autophagy, oncogenesis and viral replication appears very distant from the “canonical” one of delivering aminoacyl-tRNAs to the ribosome that has dominated the scene and much of the thinking for many decades. 相似文献
4.
V. Sinha M. J. Mills J. C. Williams 《Metallurgical and Materials Transactions A》2006,37(6):2015-2026
A faceted initiation site is observed in Ti-6242 alloy for both the cyclic and static-loading test conditions. In this experimental
study, the crystallographic orientation of the facets has been determined using the electron backscattered diffraction (EBSD)
technique in conjunction with the quantitative tilt fractography in a scanning electron microscope (SEM). Quantitative tilt
fractography analysis has been used to determine the spatial orientation of fracture facets. The results indicate that the
normal-fatigue (no-dwell) fracture facets are oriented at ∼5 deg with respect to the basal plane; the dwell-fatigue fracture
facets are oriented at ∼10 to 15 deg with respect to the basal plane and the static-loading fracture facets are oriented at
∼20 deg with respect to the basal plane. These crystallographic orientation determinations of the fracture facets at the crack-initiation
site can be used to obtain an idea about the type of loading that produced them. 相似文献
5.
Microscale wear of vitrified abrasive materials 总被引:2,自引:0,他引:2
The study of bonding hard materials such as aluminium oxide and cubic boron nitride (cBN) and the nature of interfacial cohesion between these materials and glass is very important from the perspective of high precision grinding. Vitrified grinding wheels are typically used to remove large volumes of metal and to produce components with very high tolerances. It is expected that the same grinding wheel be used for both rough and finish machining operations. Therefore, the grinding wheel, and in particular its bonding system, is expected to react differently to a variety of machining operations. In order to maintain the integrity of the grinding wheel, the bonding system that is used to hold abrasive grains in place will react differently to forces that are placed on individual bonding bridges. This paper examines the role of vitrification heat treatment on the development of strength between abrasive grains and bonding bridges, and the nature of fracture and wear in vitrified grinding wheels that are used for precision grinding applications. 相似文献
6.
Zushu Li Kenneth C. Mills Malcolm McLean Kusuhiro Mukai 《Metallurgical and Materials Transactions B》2005,36(2):247-254
The densities of three Ni-based superalloys have been measured in both liquid and mushy states by both a modified sessile
drop method (MSDM) and a modified pycnometric method (MPM) for alloys CMSX-4 and CM186LC, and for CMSX-10 alloy by MSDM only.
The surface tensions of liquid CMSX-4, CM186LC, and CMSX-10 superalloys were measured using the sessile drop method. All measurements
were carried out in a highly purified argon atmosphere with the oxygen partial pressure of less than 10−19 MPa in the gas outlet. The densities of all superalloys in both liquid and mushy states were found to decrease with increasing
temperature. The volume thermal expansion of each superalloy in the mushy state was found to be higher than that in the liquid
state. The densities determined by different methods have been critically assessed and recommended values in both liquid and
mushy states are given as a linear function of temperature for the three Ni-based superalloys. The surface tension of liquid
CMSX-4 superalloy was found to decrease with increasing temperature, while that of liquid CMSX-10 superalloy increases with
increasing temperature. The wetting behavior of liquid CM186LC on the alumina substrate was found (1) to differ significantly
from that of CMSX-4 and CMSX-10 and (2) to vary with time. A HfO2-rich layer was found in the contact area of CM186LC with the alumina substrate, which could lead to some uncertainty in the
value obtained for the surface tension determined for CM186LC. 相似文献
7.
G. Ranzi M. A. Bradford B. Uy 《International journal for numerical methods in engineering》2004,61(5):657-672
The use of the conventional semi-analytical stiffness method in finite element analysis, in which interpolation polynomials are used to develop the stiffness relationships, leads to problems of curvature locking when beam-type elements are developed for composite members with partial interaction between the materials of which it is comprised. The curvature locking phenomenon that occurs for composite steel–concrete members is quite well reported, and the general approach to minimizing the undesirable ramifications of curvature locking has been to use higher-order polynomials with increasing numbers of internal nodes. This paper presents an alternate formulation based on a direct stiffness approach rather than starting from pre-defined interpolation polynomials, and which does not possess the undesirable locking characteristics. The formulation is based on a more general approach for a bi-material composite flexural member, whose constituent materials are joined by elastic shear connection so as to provide partial interaction. The stiffness relationships are derived, and these are applied to a simply supported and a continuous steel–concrete composite beam to demonstrate the efficacy of the method, and in particular its ability to model accurately both very flexible and very stiff shear connection that causes difficulties when implemented in competitive semi-analytical algorithms. Copyright © 2004 John Wiley & Sons, Ltd. 相似文献
8.
There will always be a premium on innovation and original approaches to old problems. Engineers and designers are constantly urged to think outside the box. In space shuttle technician Arlene S. Reese's case, she decided to think outside the world of traditional, 2D drafting. Working under tough deadline pressures for a shuttle lighting installation project, Reese and her design team decided to blend digital photographs and 3D assemblies to show other contractors precisely where and how the job should be built. The result was a faster, more effective method for planning electrical projects that has earned awards for her team and continues to produce benefits for the National Aeronautics and Space Administration (NASA). Reese and the managers at NASA say the design method can apply to many architectural and engineering disciplines. 相似文献
9.
Comments on an article by Bushman and Anderson (see record 2001-17729-001). We are concerned that Bushman and Anderson's article on media violence contains data that are incorrect or irreproducible. This is a serious issue; the article has already been referenced by numerous other formal papers according to a Google scholarly article search as well as in a statement to the U.S. Senate, in legal proceedings, and in California State law (Assembly Bill 1179 in 2005). (PsycINFO Database Record (c) 2010 APA, all rights reserved) 相似文献
10.
AB Jacobson R Arora M Zuker C Priano CH Lin DR Mills 《Canadian Metallurgical Quarterly》1998,275(4):589-600
We have analyzed both conformational and functional changes caused by two large cis-acting deletions (delta 159 and delta 549) located within the read-through domain, a 850 nucleotide hairpin, in coliphage Q beta genomic RNA. Studies in vivo show that co-translational regulation of the viral coat and replicase genes has been uncoupled in viral genomes carrying deletion delta 159. Translational regulation is restored in deletion delta 549, a naturally evolved pseudorevertant. Structural analysis by computer modeling shows that structural features within the read-through domain of delta 159 RNA are less well determined than they are in the read-through domain of wild-type RNA, whereas predicted structure in the read-through domain of evolved pseudorevertant delta 549 is unusually well determined. Structural analysis by electron microscopy of the genomic RNAs shows that several long range helices at the base of the read-through domain, that suppress translational initiation of the viral replicase gene in the wild-type genome, have been destabilized in delta 159 RNA. In addition, the structure of local hairpins within the read-through region is more variable in delta 159 RNA than in wild-type RNA. Stable RNA secondary structure is restored in the read-through domain of delta 549 RNA. Our analyses suggest that structure throughout the read-through domain affects the regulation of viral replicase expression by altering the likelihood that long-range interactions at the base of the domain will form. We discuss possible kinetic and equilibrium models that can explain this effect, and argue that observed changes in structural plasticity within the read-through domain of the mutant genomes are key in understanding the process. During the course of these studies, we became aware of the importance of the information contained in the energy dot plot produced by the RNA secondary structure prediction program mfold. As a result, we have improved the graphical representation of this information through the use of color annotation in the predicted optimal folding. The method is presented here for the first time. 相似文献