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1.
The hot blow forming of magnesium sheet offers significant opportunity for forming complex, lightweight parts for automotive applications. This paper characterizes the elevated-temperature formability of AZ31 magnesium sheet materials and the effect of processing conditions on the performance of these materials. In addition, magnesium sheet application development at General Motors Corporation is reviewed.  相似文献   
2.
The application of micro- and nanofabrication processes to the development of hybrid synthetic and biological systems may enable the production of new devices such as controllable transporters, gears, levers, micropumps, or microgenerators powered by biological molecular motors. However, engineering these hybrid devices requires fabrication processes that are compatible with biological materials such as kinesin motor proteins and microtubules. In this paper, the effects of micro- and nanofabrication processing chemicals and resists on the functionality of casein, kinesin, and microtubule proteins are systematically examined to address the important missing link of the biocompatibility of micro- and nanofabrication processes needed to realize hybrid system fabrication. It is found that both casein, which is used to prevent motor denaturation on surfaces, and kinesin motors are surprisingly tolerant of most of the processing chemicals examined. Microtubules, however, are much more sensitive. Exposure to the processing chemicals leads to depolymerization, which is partially attributed to the pH of the solutions examined. When the chemicals were diluted in aqueous buffers, a subset of them no longer depolymerized microtubules and in their diluted forms still worked as resist removers. This approach broadens the application of micro- and nanofabrication processes to hybrid synthetic and biological system fabrication.  相似文献   
3.
A simple practical equivalent continuum numerical model for simulating the behavior of jointed rock mass has been extended to three-dimensional using FLAC3D. This model estimates the properties of jointed rock mass from the properties of intact rock and a joint factor (Jf), which is the integration of the properties of joints to take care of the effects of frequency, orientation, and strength of joint. A new FISH function has been written in FLAC3D specifically for modeling jointed rocks using the Duncan and Chang hyperbolic model. This model has been validated first with simple element tests at different confining pressures for different rocks with different joint configurations. Explicit modeling of the joints has also been done in element tests and results obtained compare well with the results of equivalent continuum model and also with experimental results. Further, this has been applied for a case study of a large underground power house cavern in the Himalayas. The analysis has been done under various stages of excavation, assigning a null model available in FLAC3D for simulating the excavation.  相似文献   
4.
Energy consumption is one of the important parameters to be optimized during the design of portable embedded systems. Thus, most of the contemporary portable devices feature low-power processors coupled with on-chip memories (e.g., caches, scratchpads). Scratchpads are better than traditional caches in terms of power, performance, area, and predictability. However, unlike caches they depend upon software allocation techniques for their utilization. In this paper, we present scratchpad overlay techniques which analyze the application and insert instructions to dynamically copy both variables and code segments onto the scratchpad at runtime. We demonstrate that the problem of overlaying scratchpad is an extension of the Global Register Allocation problem. We present optimal and near-optimal approaches for solving the scratchpad overlay problem. The near-optimal scratchpad overlay approach achieves close to the optimal results and is significantly faster than the optimal approach. Our approaches improve upon the previously known static allocation technique for assigning both variables and code segments onto the scratchpad. The evaluation of the approaches for ARM7 processor reports, average energy, and execution time reductions of 26% and 14% over the static approach, respectively. Additional experiments comparing the overlayed scratchpads against unified caches of the same size, report average energy, and execution time savings of 20% and 10%, respectively. We also report data memory energy reductions of 45%-57% due to the insertion of a 1024-bytes scratchpad memory in the memory hierarchy of a digital signal processor (DSP).  相似文献   
5.
In order to identify Ca2+ ligands in the putative transmembrane domain 6 of the plasma membrane Ca2+ pump, amino acids Asn879, Met882, Asp883, and Ser887 were singly altered. Asn879, Met882, and Asp883 were chosen because the corresponding amino acids have been proposed as Ca2+ ligands in the sarcoplasmic reticulum Ca2+ pump (Clarke, D. M., Loo, T. W., and MacLennan, D. H. (1990) J. Biol. Chem. 265, 6262-6267). For the alterations, a fully active truncated version of the pump was used, because the interaction of Ca2+ with the pump could be studied without interference from calmodulin binding. The mutants at Asn and Asp did not carry out ATP-supported Ca2+ uptake and formed no acylphosphate from [gamma-32P]ATP, suggesting that, like the corresponding amino acids in the sarcoplasmic reticulum Ca2+ pump, these two are Ca2+ ligands. However, all the mutants at the position of Met882 showed some activity. Indeed, the Met882--> Ile mutant was fully active at a saturating Ca2+ concentration and only the K1/2 for Ca2+ activation was shifted slightly upward. Converting the Met to Thr (which is the corresponding residue in the sarcoplasmic reticulum Ca2+ pump) reduced the activity to 20% of the wild type, further emphasizing the differences between the two Ca2+ pumps. The mutant Ser887--> Ala was expressed in greater amounts than, and had a specific activity about 50% higher than, the wild type, indicating that this serine also could not be a Ca2+ ligand and could not replace the missing Thr at position Met882.  相似文献   
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7.
The paper shows that an analytical evaluation of the power coefficient Cp for an ideal horizontal-axis wind turbine can be made via an expression giving the direct relationship of Cp and the axial induction factor a. The results obtained agree closely with those obtained numerically from the usual integral expression involving several variables.  相似文献   
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9.
The Journal of Supercomputing - A correction to this paper has been published: https://doi.org/10.1007/s11227-021-03790-9  相似文献   
10.
Verma  Amit  Dawar  Siddharth  Kumar  Raman  Navathe  Shamkant  Goyal  Vikram 《Applied Intelligence》2021,51(7):4649-4663

High-utility Itemset Mining (HUIM) finds patterns from a transaction database with their utility no less than a user-defined threshold. The utility of an itemset is defined as the sum of the utilities of its items. The utility notion enables a data analyst to associate a profit score with each item and thereof to a pattern. We extend the notion of high-utility with diversity to define a new pattern type called High-utility and Diverse pattern (HUD). The notion of diversity of a pattern captures the extent of the different categories covered by the selected items in the pattern. An application of diverse-pattern lies in the recommendation task where a system can recommend to a customer a set of items from a new class based on her previously bought items. Our notion of diversity is easy to compute and also captures the basic essence of a previously proposed diversity notion. The existing algorithm to compute frequent-diverse patterns is 2-phase, i.e., in the first phase, frequent patterns are computed, out of which diverse patterns are filtered out in the second phase. We, in this paper, give an integrated algorithm that efficiently computes high-utility and diverse patterns in a single phase. Our experimental study shows that our proposed algorithm is very efficient as compared to a 2-phase algorithm that extracts high-utility itemsets in the first phase and filters out the diverse itemsets in the second phase.

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