An enzymeimmunoassay for total thyroxine using avidin-biotin separation system and thyroxine-peroxidase conjugate

An avidin-biotin enzymeimmunoassay for total thyroxine in serum is described. Avidin was adsorbed to biotinylated bovine serum albumin coated tubes prepared with glutaraldehyde as coupling agent. In the enzymeimmunoassay, affinity purified biotinylated anti-thyroxine IgG, sample or standards, and thyroxine-horseradish peroxidase were simultaneously added to the avidin coated tubes. The bound enzymatic activity was then measured with o-phenylenediamine and H2O2. Results showed that the assay has good precision (within-assay CV% less than 10% and between assay 11.7% in hypo- and 6.9% in hyperthyroid range), good assay range (0-800 nmol/L), good sensitivity (4 nmol/L), and can be performed in 2.5 hours. The results obtained correlate well (r = 0.93) with those of an RIA.     

Influence of the cross‐sectional shape on the structure and properties of polyester fibers

The effects of the fiber cross‐sectional shape on the structure and properties of polyester fibers were investigated. Fully drawn yarn (FDY) polyester fibers (167 dtex and 48 filaments) were produced under the same spinning conditions used in a spinning plant. The only difference between the fibers was their cross‐sectional shapes. Four different cross‐sectional shapes were chosen for the experimental work: round, hollow‐round, trilobal, and hollow‐trilobal. The crystallinity and values of the maximum stress, maximum strain, modulus, yield stress, shrinkage in boiling water, and unevenness of the fibers were determined. The difference in the cross‐sectional shapes influenced the modulus, maximum strain, yield stress, and shrinkage in boiling water. No effects on the crystallinity and maximum stress were observed. The results suggested that the hollow fibers had higher amorphous orientation than the full fibers. The hollow‐round fiber had the highest unevenness value. © 2006 Wiley Periodicals, Inc. J Appl Polym Sci 103: 2615–2621, 2007     

Design of a Commercial Hybrid VTOL UAV System

For the last four decades Unmanned Air Vehicles (UAVs) have been extensively used for military operations that include tracking, surveillance, active engagement with weapons and airborne data acquisition. UAVs are also in demand commercially due to their advantages in comparison to manned vehicles. These advantages include lower manufacturing and operating costs, flexibility in configuration depending on customer request and not risking the pilot on demanding missions. Even though civilian UAVs currently constitute 3 % of the UAV market, it is estimated that their numbers will reach up to 10 % of the UAV market within the next 5 years. Most of the civilian UAV applications require UAVs that are capable of doing a wide range of different and complementary operations within a composite mission. These operations include taking off and landing from limited runway space, while traversing the operation region in considerable cruise speed for mobile tracking applications. This is in addition to being able traverse in low cruise speeds or being able to hover for stationary measurement and tracking. All of these complementary and but different operational capabilities point to a hybrid unmanned vehicle concept, namely the Vertical Take-Off and Landing (VTOL) UAVs. In addition, the desired UAV system needs to be cost-efficient while providing easy payload conversion for different civilian applications. In this paper, we review the preliminary design process of such a capable civilian UAV system, namely the TURAC VTOL UAV. TURAC UAV is aimed to have both vertical take-off and landing and Conventional Take-off and Landing (CTOL) capability. TURAC interchangeable payload pod and detachable wing (with potential different size variants) provides capability to perform different mission types, including long endurance and high cruise speed operations. In addition, the TURAC concept is to have two different variants. The TURAC A variant is an eco-friendly and low-noise fully electrical platform which includes 2 tilt electric motors in the front, and a fixed electric motor and ducted fan in the rear, where as the TURAC B variant is envisioned to use high energy density fuel cells for extended hovering time. In this paper, we provide the TURAC UAV’s iterative design and trade-off studies which also include detailed aerodynamic and structural configuration analysis. For the aerodynamic analysis, an in-house software including graphical user interface has been developed to calculate the aerodynamic forces and moments by using the Vortex Lattice Method (VLM). Computational Fluid Dynamics (CFD) studies are performed to determine the aerodynamic effects for various configurations For structural analysis, a Finite Element Model (FEM) of the TURAC has been prepared and its modal analysis is carried out. Maximum displacements and maximal principal stresses are calculated and used for streamlining a weight efficient fuselage design. Prototypes have been built to show success of the design at both hover and forward flight regime. In this paper, we also provide the flight management and autopilot architecture of the TURAC. The testing of the controller performance has been initiated with the prototype of TURAC. Current work focuses on the building of the full fight test prototype of the TURAC UAV and aerodynamic modeling of the transition flight.     

A novel fuzzy multi-criteria decision framework for sustainable supplier selection with incomplete information

Both academic and corporate interest in sustainable supply chains has increased in recent years. Supplier selection process is one of the key operational tasks for sustainable supply chain management. This paper examines the problem of identifying an effective model based on sustainability principles for supplier selection operations in supply chains. Due to its multi-criteria nature, the sustainable supplier evaluation process requires an appropriate multi-criteria analysis and solution approach. The approach should also consider that decision makers might face situations such as time pressure, lack of expertise in related issue, etc., during the evaluation process. The paper develops a novel approach based on fuzzy analytic network process within multi-person decision-making schema under incomplete preference relations. The method not only makes sufficient evaluations using the provided preference information, but also maintains the consistency level of the evaluations. Finally, the paper analyzes the sustainability of a number of suppliers in a real-life problem to demonstrate the validity of the proposed evaluation model.     

A novel hybrid MCDM approach based on fuzzy DEMATEL, fuzzy ANP and fuzzy TOPSIS to evaluate green suppliers

It is well known that “green” principles and strategies have become vital for companies as the public awareness increased against their environmental impacts. A company’s environmental performance is not only related to the company’s inner environmental efforts, but also it is affected by the suppliers’ environmental performance and image. For industries, environmentally responsible manufacturing, return flows, and related processes require green supply chain (GSC) and accompanying suppliers with environmental/green competencies. During recent years, how to determine suitable and green suppliers in the supply chain has become a key strategic consideration. Therefore this paper examines GSC management (GSCM) and GSCM capability dimensions to propose an evaluation framework for green suppliers. However, the nature of supplier selection is a complex multi-criteria problem including both quantitative and qualitative factors which may be in conflict and may also be uncertain. The identified components are integrated into a novel hybrid fuzzy multiple criteria decision making (MCDM) model combines the fuzzy Decision Making Trial and Evaluation Laboratory Model (DEMATEL), the Analytical Network Process (ANP), and Technique for Order Performance by Similarity to Ideal Solution (TOPSIS) in a fuzzy context. A case study is proposed for green supplier evaluation in a specific company, namely Ford Otosan.     

Biosorption of Acid Red P-2BX by lichens as low-cost biosorbents

The aim of this study is to examine the dye biosorption properties of lichen species called Cladonia convoluta and Evernia prunastri. Since lichens are extensively found in the environment, their suitability as a cheap adsorbent has been investigated in this study. The optimal parameters for textile dye biosorption were also determined. The dried lichen biomass showed better dye biosorption capacity than ash lichen biomass. C. convoluta had better dye biosorption capacity than E. prunastri. Dye biosorption rate was found as 71.41% at optimal conditions. This study concluded that C. convoluta was a successful and cheap biosorbent for treatment of water contaminated by Acid Red P-2BX dye.     

Porous polyurethane film fabricated via the breath figure approach for sustained drug release

The breath figure (BF) method is an effective process for fabricating porous polymeric films. In this study, we fabricated porous polymer films from thermoplastic polyurethane (PU) through static BF with CHCl₃ as a solvent under 55–80% relative humidity. The porous PU films were prepared within various pore structures and sizes, which were adjustable, depending on the fabrication conditions. The humidity and exposure time were examined as variable parameters affecting the surface morphology, wettability, and cytotoxicity. Atorvastatin calcium, a hyperlipidemic agent, was loaded into the porous films during the casting process, and the drug-loading and drug-releasing behaviors of the porous PU membranes were evaluated. Approximately 60–80% of the drug was released in 14 days. The films exhibited sustained drug-release performances because of the hydrophobicity and nonbiodegradable nature of PU for perivascular drug administration. © 2019 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2019 , 136, 47658.     

UV curable lens production using molecular weight controlled PEEK based acrylic oligomer (Ac-PEEK)

We produced UV curable lenses with properties blocking short wave UV light. In the UV-curable formulations, we used an oligomer (Ac-PEEK) with another urethan oligomer (Mw = 2000). Radically active, molecular weight controlled Ac-PEEK was obtained by reacting 2-hydroxyl ethyl methacrylate with molecular- weight- controlled and isocyanate terminated PEEK (Mn = 4500). We characterized all synthesized monomer, oligomer and optical materials with UV/Vis spectrophotometer with interferogram, elemental analyser, mass spectrophotometer, proton nuclear magnetic resonance, Fourier transform infrared spectroscopy, thermal gravimetric analyzer, differential scanning calorimeter, scanning electron microscopy and gas chromatography. Results suggested that newly synthesized oligomer with the structure of PEEK absorbs short wave UV-light. Ageing tests [ISO 11979-5, Ophthalmic implants—intraocular lenses (IOL)—Part 5: Biocompatibility] performed on the IOL materials were successful. High contact angle of the obtained lenses suggests that all lenses were hydrophobic and SEM results revealed that lenses are morphologically homogeneous. Based on all positive properties just mentioned, we safely conclude that the lenses produced in this study are very promising for IOL production.