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排序方式: 共有623条查询结果,搜索用时 31 毫秒
1.
K Hisatomi N Hayashida E Tayama M Ohashi T Isomura K Kosuga K Oishi 《Canadian Metallurgical Quarterly》1993,94(8):791-795
Glucagon has been demonstrated to stimulate the uptake of bile acid in isolated rat hepatocytes (Am. J. Physiol., 249, G427 (1985)). In the present study, we determined the influence of glucagon on the hepatic transport of a bile acid, taurocholate (TCA), in isolated rat livers. A single-pass perfusion and a rapid-injection, multiple indicator dilution method were employed. The hepatic availability at steady-state was 0.04. With the presence of glucagon in the perfusate (from 10(-9) to 10(-7) M), the bile flow rate was stimulated by 30%, while hepatic availability was decreased from 0.04 to 0.02 with a stepwise increase in glucagon concentration. Thirty min after the infusion of glucagon (300 nM), [3H]TCA and [14C]inulin were injected in a bolus state into the portal vein, and the outflow was collected at 1.0 s intervals over 30 s. Glucagon decreased the instantaneous hepatic availability by 50% compared to the control level, and was thus compatible with the steady-state experiments. In the control experiment, the influx clearance (PSinf) was 20 times higher than the efflux clearance (PSeff). Glucagon (300 nM) in the perfusate enhanced PSinf by 50% of the control, whereas sequestration clearance (CLseq) and the biliary excretion rate constant remained unchanged. PSeff was stimulated to 2 times the control, but still remained much smaller than CLseq. Based on the comparison of PSinf, PSeff and CLseq, the rate-determining process of TCA hepatic elimination was the influx process in both the presence and absence of glucagon. Taken together, the enhancement of the influx process was responsible for the decrease in TCA hepatic availability caused by glucagon.(ABSTRACT TRUNCATED AT 250 WORDS) 相似文献
2.
Oishi Shigehiro; Diener Ed; Choi Dong-Won; Kim-Prieto Chu; Choi Incheol 《Canadian Metallurgical Quarterly》2007,93(4):685
The authors examined cultural and individual differences in the relation between daily events and daily satisfaction. In a preliminary study, they established cross-cultural equivalence of 50 daily events. In the main study, participants in the United States, Korea, and Japan completed daily surveys on the 50 events and daily satisfaction for 21 days. The multilevel random coefficient model analyses showed that (a) the within-person association between positive events and daily satisfaction was significantly stronger among Asian American, Korean, and Japanese participants than among European American participants and (b) the within-person association between positive events and daily satisfaction was significantly weaker among individuals high in global life satisfaction than among those low in global life satisfaction. The findings demonstrate a weaker effect of positive events on daily well-being among individuals and cultures high in global well-being. (PsycINFO Database Record (c) 2010 APA, all rights reserved) 相似文献
3.
Junya Kondoh Yoichi Tomii Katsuhiro Kawachi 《Journal of the American Ceramic Society》2003,86(12):2093-2102
Methods of suppressing decreased conductivity in 8 mol% Y2 O3 -stabilized–92 mol% ZrO2 (8YSZ) with aging were investigated. Different amounts of Sc2 O3 were doped into 8YSZ. The electrochemical properties of Sc2 O3 -doped 8YSZ were measured, and the microstructural and local structural changes were characterized. The present results indicate that an appropriate amount of Sc2 O3 doping, 3 or 4 mol%, effectively suppresses decreased conductivity with aging in 8YSZ. 相似文献
4.
Plane deformation of anisotropic beams with narrow rectangular cross sections exhibits coupling of stretching, bending and transverse shearing. For anisotropic cantilever beams with a stiff end-cap under end forces and an end couple, assessments were made for approximate solutions by comparing these with numerically exact finite element (FE) solutions. Specific attention is given to point-wise or approximate satisfaction of the end-fixity conditions. As approximate methodologies, (i) the elementary polynomial form of Airy's stress function for the plane stress problem in a rectangular region, (ii) a Timoshenko-type beam theory, and (iii) the Bernoulli-Euler beam theory were selected. Among these, only the polynomial form of Airy's stress function violates the point-wise end-fixity conditions. Both the polynomial Airy stress function and the Timoshenko-type beam theory successfully model the effects of transverse shear deformation and the coupling of stretching and transverse deflection. Analytical solutions demonstrate that the normal shear coupling effect increases linearly with the thickness-to-span ratios in axial normal stress and axial displacement, while the coupling manifests quadratically in transverse displacement. The comparison of end displacements with the numerically exact FE solutions indicates that the polynomial form of Airy's stress function is no better than the Timoshenko-type beam theory. Similar conclusions were reached for the problem of uniformly loaded cantilever beams. It has been found that the accurate prediction of the deformation of thick anisotropic beams with significant normal-shear coupling requires the use of higher order theories. 相似文献
5.
6.
Kunio Mori Wataru Ibashi Hidetoshi Hirahara Yoshiyuki Oishi Masanari Katayama 《应用聚合物科学杂志》1995,58(13):2451-2458
2-Dibutylamino-1,3,5-triazine-4,6-dithiol (DB) and a mixture of DB and triallylisocyanurate (TAIC) were used as a lubricant during steel wire drawing due to a dry process. DB gave a polymer film with 180 nm in thickness to wire surfaces during the wire drawing. The polymer film had a disulfide structure on the backbone and contained a small amount of DB monomer and olygomer. Molecular weight and polymer weight increased with the drawing rate. The mixture of DB and TAIC gave mainly a three-dimensional polymer film with 225 nm in thickness to wire surfaces during drawing. The polymer film insoluble in THF had mono and disulfide structures and contained a small amount of linear polymer, DB, and TAIC. Such tribological polymerizations are estimated as follows: DB produces dithiyl radicals on a nascent surface formed during drawing and in the presence of oxygen and heat. The dithiyl radicals were polymerized by coupling with each other to give disulfide bonds or added to allyl groups in TAIC to give monosulfide bonds. It is concluded that this technique should be possible to use for unifying metal processing and surface treatment. © 1995 John Wiley & Sons, Inc. 相似文献
7.
2016年,长江中下游发生了区域性大洪水。为保证洪水预报的水文资料需求,长江委水文局通过建立的由水文监测管理体系、水文监测服务体系、水文监测技术支撑体系、水文监测质量保障体系等四大部分组成的水文监测体系创新与关键技术,以“巡测优先、驻巡结合、测报自动、应急补充”的新型水文监测模式,大大提升了防洪监测的能力和水平。与往次防洪监测比较,在应对2016年的大洪水的过程中,长江水文测验的新型模式带来了测洪能力、技术水平、准确度、时效性的系统性提升,其中,流量测验时间缩短了73%~83%,水情信息到报率和准确率达到99.95%,远远高于国家标准。 相似文献
8.
The recoverable shear strain (SR) for the liquid crystal‐forming hydroxypropyl cellulose solutions was determined by means of a concentric cylinder rotational apparatus as functions of shear stress prior to recovery and concentration of the solutions at 30°C. SR greatly depended on shear stress and concentration; the phase of the solution (the single phase or biphase) governed the dependences of SR on stress and concentration. SR increased with increasing stress for the single phase and decreased for the biphase. SR seemed to be related to the die swell (B): SR ∝ Bn. SR exhibited a maximum and a minimum with respect to concentration. SR for the cellulosic cholesteric liquid crystalline solutions was greater than that for the isotropic solutions. A model was proposed for explaining the greater SR. © 2002 Wiley Periodicals, Inc. J Appl Polym Sci 85: 865–872, 2002 相似文献
9.
Hai -Hang Li Masafumi Inoue Hiroyuki Nishimura Junya Mizutani Eiji Tsuzuki 《Journal of chemical ecology》1993,19(8):1775-1787
Phenolic compounds have been identified as the most common allelochemicals produced by higher plants. Inhibitions of cinnamic acid, its related phenolic derivatives, and abscisic acid (ABA) on seedling growth and seed germination of lettuce were studied.trans-Cinnamic acid, ando-,m-, andp-coumaric acids inhibited the growth of etiolated seedlings of lettuce at concentrations higher than 10–4 M and seed germination above 10–3 M. Coumarin inhibited seedling growth and seed germination at 10–5 M or above. Chlorogenic acid inhibited seedling growth above 10–4 M, but did not inhibit seed germination at 10–5–5×10–3 M. Low concentrations (below 10–3 M) of caffeic and ferulic acids promoted the elongation of hypocotyls, but higher concentrations (over 10–3 M) inhibited seedling growth and seed germination. These phenolic compounds and abscisic acid had additive inhibitory effects both on seedling growth and seed germination. The inhibition on lettuce was reversed by caffeic and ferulic acids at concentrations lower than 10–3 M except for the inhibition of germination by coumarin. These results suggest that in naturetrans-cinnamic acid,o-, m-, p-coumaric acids, coumarin, and chlorogenic acid inhibit plant growth regardless of their concentration. However, caffeic and ferulic acids can either promote or inhibit plant growth according to their concentration. 相似文献
10.
In order to develop an energy-saving copper recycling process from wastes, electrochemical measurements were conducted in ammoniacal alkaline solutions containing Cu(I) ions and an ammonium salt of sulfate, chloride or nitrate. The results of each system were then compared. The polarization measurements suggested that the voltage required for the electrode process is lower in the chloride and nitrate systems than that in the sulfate system. The cathode current efficiency during the copper electrodeposition varied from 39 to 97% and increased with current density in the chloride and sulfate systems. In the nitrate system, the lowest cathode current efficiency of 30% was observed because of nitrate ion reduction. Based on these results, the power consumption required for the electrowinning stage of the copper recycling process was calculated. Among these three systems, the chloride system showed the lowest power consumption of 500 kWh t−1 at the current density of 200 A m−2, which is about 25% of the conventional copper electrowinning process from a copper sulfate-sulfuric acid solution. 相似文献