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1.
During October 1992 an increase in the number of isolates of Salmonella mikawasima, a rare serotype, was noted including a cluster of nine cases in the South West Thames region. A case control study was conducted and univariate analysis showed a statistical association between illness and eating at take-away A for cases compared with household controls (P = 0.003) and with neighbourhood controls (P = 0.0245). Cases were also more likely to have eaten kebabs than were controls or average take-away A customers, implicating doner kebabs as the most likely vehicle of infection. Plasmid profile analysis of the nine cases' isolates showed them to be indistinguishable and to be characterized by a single plasmid of approximately 60 MDa. The original source of the Salmonella mikawasima contamination was not determined, but food preparation practices for kebabs at take-away A were insufficient to protect against illness if contaminated. This outbreak was only recognized because of the unusual serotype, but could be an indication of a more widespread problem with doner kebabs.  相似文献   
2.
The structures of a number of hydroxide and oxyhydroxide minerals have previously been reported without the hydrogen positions explicitly defined. Here we use two atomic scale computer simulation techniques, one based on classical ionic potentials, the other on density functional theory (DFT), to predict these positions. The aim is not only to provide data that can be used as the basis for future experimental structure optimizations but also model parameters that can be used to predict complex hydroxide structures. The efficacy of the approach is demonstrated through the comparison of predicted and experimental data for minerals whose hydrogen positions are known.  相似文献   
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Water and sediment samples from 29 locations in the Detroit and St. Clair rivers were analyzed for the highly toxic tri-n-butyltin (Bu3Sn+) species and for the less toxic di-n-butyltin (Bu2Sn2+) and n-butyltin (BuSn3+) species and inorganic tin. In general, locations sampled in the St. Clair River were less contaminated with butyltin species than those in the Detroit River. Inorganic tin and BuSn3+ were detected in over 90% of all subsurface water samples, while Bu2Sn2+ and Bu3Sn+ were detected in 45 and 28% of the same samples, respectively. The highest concentration ofBu3Sn+ in subsurface water, 5.9 × 10?10 mol Sn/L, was at the mouth of the Ecorse River, a tributary of the Detroit River. The three butyltin species and inorganic tin were also detected in 23–46% of all sediment samples. The highest concentrations of Bu3Sn+ in sediment were found close to the mouths of the River Rouge, another tributary of the Detroit River, and the Ecorse River, and were 6.2 × I0–7 and 1.7 × I0–7 mol Sn/kg dry weight, respectively, for the top 2 cm of sediment.  相似文献   
5.
Earlier work on the low temperature solution polyamidation of bisacid A2 has raised a number of structural problems. Work carried out more recently showed that the problem of apparent nonisostoichiometry could be reasonably satisfactorily explained. The present paper reports the synthesis and investigates the properties of a further series of polyamides based upon Bisacid A2. More importantly, however, a detailed characterization and evaluation of the new polymers with respect to their structures is presented. This enabled us to compare the various structures in the light of the experimental evidence provided by a number of analytical and spectroscopic techniques, solution behavior, molecular weight, and thermal, morphological, and mechanical properties. Some work was also done on the effect of incorporating a small amount of a trifunctional monomer into the polyamide system.  相似文献   
6.
Renal scarring is considered a criterion of reflux nephropathy and the end stage of pyelonephritis. Prednisolone, a strong anti-inflammatory drug, at doses of 1 or 2 mg/kg prevented renal scarring in rats following infection with Serratia marcescens. Four or 8 mg/kg of prednisolone, however, did not inhibit renal scar formation. In a time course experiment, renal scarring was prevented when 4-day treatment with prednisolone was initiated 2, 5, or 13 days after infection. These results show that prednisolone is effective in preventing such scarring and suggest the clinical use of this drug for preventing renal scar formation after pyelonephritis and reflux nephropathy.  相似文献   
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Approximate equations are derived that allow calculation of the component values for a multiple-mode Mason equivalent circuit for acoustic transducers. The experimental approach required to obtain the data from which to derive the equivalent circuit is also described. The equations have been tested for accuracy, and the approach described here yields useful information for the system designer. Iterative procedures can be applied to further refine the calculated values.  相似文献   
9.
Pattern selection methods have been traditionally developed with a dependency on a specific classifier. In contrast, this paper presents a method that selects critical patterns deemed to carry essential information applicable to train those types of classifiers which require spatial information of the training data set. Critical patterns include those edge patterns that define the boundary and those border patterns that separate classes. The proposed method selects patterns from a new perspective, primarily based on their location in input space. It determines class edge patterns with the assistance of the approximated tangent hyperplane of a class surface. It also identifies border patterns between classes using local probability. The proposed method is evaluated on benchmark problems using popular classifiers, including multilayer perceptrons, radial basis functions, support vector machines, and nearest neighbors. The proposed approach is also compared with four state-of-the-art approaches and it is shown to provide similar but more consistent accuracy from a reduced data set. Experimental results demonstrate that it selects patterns sufficient to represent class boundary and to preserve the decision surface.  相似文献   
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