Transient simulation of heterojunction photodiodes-part II:analysis of resonant cavity enhanced photodetectors

The high-speed response properties of resonant cavity enhanced (RCE) photodetectors have been investigated. The limitations on the high-speed performance of photodiodes and the advantages of RCE-detection are discussed. Transient response of heterojunction photodiodes under pulsed optical illumination has been simulated using the method described in Part I. Results on conventional AlGaAs/GaAs and RCE GaAs/InGaAs heterojunction p-i-n photodiodes are presented. For small area detectors, almost 50% bandwidth improvement along with a two-fold increase in efficiency is predicted for RCE devices over optimized conventional photodiodes. A nearly three-fold enhancement in the bandwidth-efficiency product was shown     

An experimental and three-dimensional numerical study of natural convection heat transfer between two horizontal parallel plates

In this study, experimental and three-dimensional numerical studies were performed to investigate the effects of plate spacing and temperature difference on natural convection between isothermally heated upward-facing lower horizontal plate and externally insulated horizontal upper plate. Air is used as the heat transfer medium. Rayleigh number varied in the 1108–2.339 × 10⁵ range. Several numerical simulations for three-dimensional steady laminar and turbulent flows heat transfer were carried out using a commercial CFD code Fluent 6.2. Results have shown that there is a good agreement between the numerical and present experimental results as well as with available data in literature.     

Investigating the effect of production process of ball mill refiner on some physical quality parameters of compound chocolate: response surface methodology approach

Chocolate compound was produced using ball mill refiner, and the effect of agitator shaft speed and refining time on the physical quality parameters (particle size, colour and steady‐state rheology) of compound chocolate was determined using response surface methodology. The shaft speed and refining time range were selected between 40–60 r.p.m. and 10–30 min, respectively. Determination coefficient of the models established for particle size, Newtonian viscosity and colour parameters (brightness, chroma and hue angle) were found to be very close to unity. Increasing shaft speed and time induced a reduction in particle size and an increase in viscosity of the samples. Temperature sweep test was also performed, and the obtained data were successfully fitted to Arrhenius equation to calculate the corresponding parameters representing temperature dependency of the compounds. The results highlighted that the establishment of such models can provide essential information in terms of optimisation of production processes regarding usage purpose of the compound chocolate.     

Kinome-Wide Profiling Identifies Human WNK3 as a Target of Cajanin Stilbene Acid from Cajanus cajan (L.) Millsp.

Pigeon Pea (Cajanus cajan (L.) Millsp.) is a common food crop used in many parts of the world for nutritional purposes. One of its chemical constituents is cajanin stilbene acid (CSA), which exerts anticancer activity in vitro and in vivo. In an effort to identify molecular targets of CSA, we performed a kinome-wide approach based on the measurement of the enzymatic activities of 252 human kinases. The serine-threonine kinase WNK3 (also known as protein kinase lysine-deficient 3) was identified as the most promising target of CSA with the strongest enzymatic activity inhibition in vitro and the highest binding affinity in molecular docking in silico. The lowest binding affinity and the predicted binding constant pKi of CSA (−9.65 kcal/mol and 0.084 µM) were comparable or even better than those of the known WNK3 inhibitor PP-121 (−9.42 kcal/mol and 0.123 µM). The statistically significant association between WNK3 mRNA expression and cellular responsiveness to several clinically established anticancer drugs in a panel of 60 tumor cell lines and the prognostic value of WNK3 mRNA expression in sarcoma biopsies for the survival time of 230 patients can be taken as clues that CSA-based inhibition of WNK3 may improve treatment outcomes of cancer patients and that CSA may serve as a valuable supplement to the currently used combination therapy protocols in oncology.     

Polarization sensing with resonant cavity enhanced photodetectors

We describe a new method of sensing the linear polarization of light using resonant cavity enhanced (RCE) photodetectors. The RCE detectors are constructed by integrating a thin absorption region into an asymmetric Fabry-Perot cavity. The top reflector is formed by the semiconductor air interface while the bottom mirror is a distributed Bragg reflector (DBR). Quantum efficiency of these RCE devices can be controlled by tuning the cavity length by recessing the top surface of the detector for off-normal incidence of light the reflectivity of the semiconductor-air interface can be significantly different for TE(s) and TM(p) polarizations. A pair of monolithically integrated RCE photodetectors with cavity lengths tuned for resonance and antiresonance provide a large contrast in response to TE and TM polarizations. An alternative polarization sensor can be formed by vertically integrating a conventional and a RCE photodetector. We show that a large contrast in the TE/TM responsivities of the vertical cavity polarization detectors (VCPD) can be achieved, thus combining detection and polarization sensing in a single mesa semiconductor device. These devices alleviate the problems associated with the bulkiness and critical alignment constraints of the conventional sensors based on polarizing filters or splitters and have potential for fabrication of monolithic smart pixels and imaging arrays     

Mechanical and microstructural properties of low-carbon steel-plate-reinforced gray cast iron

In the present experimental study, strengthening of gray cast iron by reinforcing with steel plates was investigated in the as-cast and normalized conditions. Normalizing heat treatments were applied to the specimens at temperatures of 800 °C and 850 °C. Three-point bend specimens were manufactured from gray cast iron and also from gray cast iron with reinforced steel plates. Flexural strengths of the steel-plate-reinforced cast iron were calculated for four distinct volume fractions (V_r = 0.04, 0.08, 0.12, and 0.16). The current study shows that the steel-plate-reinforced gray cast iron has higher flexural strength and flexural modulus than the cast iron without reinforcement. The flexural strength considerably increases with slight increase in normalization temperature. Optical and scanning electron microscopy analyses were used to examine flake morphology and microstructures of gray cast iron and steel-plate-reinforced gray cast iron. It is noted that carbon diffuses from the gray cast iron to the steel plates. A transition region containing partially dissolved graphite and having high hardness was observed due to the carbon diffusion.     

Flow-Boundary Effects on Critical Submergence of Intake Pipe

In this study, the effects of intake-pipe blockage and location of impervious boundaries on critical submergence of an intake pipe are presented. Experiments were conducted on a horizontal intake pipe sited in a dead-end canal flow. Theoretical results and available experimental data are compared. It is shown that, as the distance between the intake-pipe entrance and the dead end gets smaller than the critical submergence depth, the deviation between theoretical and experimental results increases. A potential flow solution still gives acceptable results when this distance is smaller than the critical submergence, but it overpredicts by about 80% when the distance between the intake-pipe entrance becomes much smaller than the critical submergence depth.