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1.
G Melaku 《Canadian Metallurgical Quarterly》1996,73(7):459-462
Seventy-nine children with foreign body aspiration (FBA) were treated at the Ethio-Swedish Children's Hospital in Addis Ababa, Ethiopia, over a seven year period, from September 1987 to August 1994. There were 55 boys and 24 girls with a mean age of 3.4 years. Only 15 (19%) children presented within 24 hours of aspiration. A definite or suggestive history of FBA was obtained in 68 (86%) children. Abnormal radiologic findings were present in 60 (76%) cases. Correct diagnosis was delayed or missed in 16 (20%) cases. Bronchoscopic extraction of foreign bodies was made in 62 out of 69 bronchoscoped cases. Three children coughed up the foreign bodies spontaneously. Nine (11%) children died, six before, two during and one after bronchoscopy. Late presentation, delay in diagnosis and intervention as well as missed diagnosis were major causes of prolonged morbidity and high mortality. Considering FBA early in the differential diagnosis of unexplained pulmonary problems, early bronchoscopy for such cases and prompt bronchoscopic extraction of aspirated foreign bodies are stressed to reduce and eventually avoid the high morbidity and mortality associated with FBA in children. 相似文献
2.
Part III: the influence of serial repitching of Saccharomyces pastorianus on the production dynamics of some important aroma compounds during the fermentation of barley and gluten‐free buckwheat and quinoa wort
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Matjaž Deželak Mekonnen Melaku Gebremariam Martin Zarnkow Thomas Becker Iztok Jože Košir 《Journal of the Institute of Brewing》2015,121(3):387-399
The present paper is the last report of a comprehensive study regarding the influence of the serial repitching of Saccharomyces pastorianus TUM 34/70 on the composition of a barley, buckwheat or quinoa fermentation medium. In particular, it focuses on the production dynamics of important volatile compounds typically associated with the aroma of beer. Samples were taken every 24 h after 11 serial repitchings of a single starter culture, analysed for the particular aroma compound content by distillation followed by gas chromatography with flame ionization detection. The term ‘serial repitching factor’ is used for the first time to support the visual evaluation of the influence of serial repitching. Results showed that the levels of methanol in the quinoa wort fermentation were only slightly higher than in barley and in practical terms independent of successive fermentation. The behaviour of acetaldehyde in quinoa was similar to that in barley. However, there was a final 2‐fold lower production of some important aroma compounds compared with barley and buckwheat and for this reason quinoa cannot be recommended as a gluten‐free substitute to produce a bottom‐fermented beer. Regarding the buckwheat wort fermentation, a 2‐ to 3‐times lower final acetaldehyde content than in barley is desirable, whereas a relatively high methanol content is not desirable. Barley and buckwheat showed comparable sum concentrations and similar overall profiles of some important aroma compounds. From this perspective, buckwheat appears to be a promising substitute for barley as a brewing raw material. The overall conclusions of our comprehensive study (Parts I–III) are that buckwheat shows adequate brewing properties to substitute for barley in the commercial preparation of a bottom‐fermented gluten‐free beer‐like beverage, and yeast can be repitched at least 11 times. In contrast, quinoa in practical terms shows no substitutional potential for barley in beer; however, it has many nutritious advantages, thus the commercial preparation of a unique, bottom‐fermented gluten‐free ‘non‐beer‐like’ beverage – where the yeast could be repitched six times at most – appears feasible. Copyright © 2015 The Institute of Brewing & Distilling 相似文献
3.
Part II: the influence of the serial repitching of Saccharomyces pastorianus on the uptake dynamics of amino acids during the fermentation of barley and gluten‐free buckwheat and quinoa wort
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Matjaž Deželak Mekonnen Melaku Gebremariam Martin Zarnkow Thomas Becker Iztok Jože Košir 《Journal of the Institute of Brewing》2015,121(3):370-386
The present paper is part of a comprehensive study regarding the influence of the serial repitching of Saccharomyces pastorianus TUM 34/70 on the composition of the barley, buckwheat and quinoa fermentation medium. In particular, it focuses on the uptake dynamics of amino acids during 11 successive fermentations. Samples were taken every 20 h after pitching, analysed for the particular amino acid content and statistically evaluated. The term ‘completion time’ (t95), here defined as the percentage attenuation time necessary for ~95% of the total assimilation, has been introduced. In addition, ‘the serial repitching factor’ is used for the first time to support the visual evaluation of the influence of serial repitching. Amino acids that were essentially affected by serial repitching were glutamine, arginine, alanine and tryptophan in barley, aspartate, glutamate and tryptophan in buckwheat, and all in the quinoa wort fermentation. As opposed to buckwheat and quinoa, in barley the amino acids behaved more or less independently from each other, which for buckwheat and quinoa indicates a more general systemic change in the yeast. From the amino acids point of view, buckwheat can be fully regarded as a suitable gluten‐free substitute for barley beer since the amino acid assimilation was very consistent and hardly influenced by the serial repitching, especially regarding the final amino acid assimilation. In the case of quinoa, the assimilation of all amino acids became significantly affected after the sixth fermentation and quinoa is probably unsuitable for the production of beer‐like beverages. Results suggest no substitutional potential of quinoa for barley beer, but if a nutrient‐rich beverage of choice from quinoa malt is intended to be prepared, it seems that the serial repitching is limited to six fermentations at most. Copyright © 2015 The Institute of Brewing & Distilling 相似文献
4.
Tekle-Haimanot R Melaku Z Kloos H Reimann C Fantaye W Zerihun L Bjorvatn K 《The Science of the total environment》2006,367(1):182-190
This paper analyzes the most extensive database on fluoride distribution in Ethiopia. Of the total 1438 water samples tested, 24.2% had fluoride concentrations above the 1.5 mg/l recommended optimum concentration recommended by WHO. Regionally, by far the highest fluoride levels were recorded in the Rift Valley, where 41.2% of all samples exceeded the 1.5 mg/l level. Only 1.0% of the samples from the central and northwestern highlands and 10.0% in the southeastern highlands exceeded 1.5 mg/l. Larger proportions of deep wells (50.0%) and hot springs (90.0%) than shallow wells (27.2%) and cold springs (12.6%) exceeded the 1.5 mg/l level. The highest fluoride concentrations were recorded for Rift Valley lakes Shala (264.0 mg/l) and Abijata (202.4 mg/l) and the lowest in Lake Tana, and rivers, wells and springs in the highlands. The fluoride concentrations of the Awash River, which originates in the highlands and flows through the Rift Valley, increase downstream, giving concern over the current diversion of high-fluoride water from Lake Beseka. Of the various flourosis prevention methods tried in Ethiopia, the treatment of surface water has been shown to be the most feasible and effective for towns and large commercial farms in the Rift Valley, although defluoridation methods should be considered for smaller rural communities. 相似文献
5.
Tilahun Shimeles Park Do Su Taye Adanech Melaku Jeong Cheon Soon 《Food science and biotechnology》2017,26(2):473-479
Food Science and Biotechnology - This study was conducted to assess the physicochemical changes and overall nutritional implications of greenhouse-grown “TY Megaton” and... 相似文献
6.
Part I: the influence of serial repitching of Saccharomyces pastorianus on the uptake dynamics of metal ions and fermentable carbohydrates during the fermentation of barley and gluten‐free buckwheat and quinoa wort
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Matjaž Deželak Mekonnen Melaku Gebremariam Martin Zarnkow Thomas Becker Iztok Jože Košir 《Journal of the Institute of Brewing》2015,121(3):356-369
Recently, research has been focusing on the use of alternative raw materials for brewing purposes and gluten‐free beer‐like beverages from malted buckwheat and quinoa are of commercial interest. A common commercial process involves the serial repitching of the yeast biomass, but this has not been described using buckwheat and quinoa wort fermentations. Our research studies (Parts I–III) explored the serial repitching of the yeast strain Saccharomyces pastorianus TUM 34/70 on the composition of a barley, buckwheat and quinoa fermentation medium. The present paper focuses on the fermentation performance and the uptake dynamics of metal ions and fermentable carbohydrates. Both pseudocereals showed high variations in all of the attributes examined during successive fermentations. In buckwheat the differences between successive fermentations were similar to those observed with barley, whereas differences in quinoa varied quite significantly from those observed with barley and showed a directional trend, suggesting a general weakening of the yeast from the sixth successive fermentation onward. In particular, the assimilation of the fermentable carbohydrates lessened and metal ion uptake appeared poorly controlled. It was concluded that buckwheat showed good potential for serial repitching of S. pastorianus TUM 34/70, whereas serial repitching of a quinoa wort appeared to be limited to five or six fermentations. Copyright © 2015 The Institute of Brewing & Distilling 相似文献
7.
Cheng-You Wu Ashenafi Zeleke Melaku Fasih Bintang Ilhami Chih-Wei Chiu Chih-Chia Cheng 《International journal of molecular sciences》2022,23(8)
Synthetic bioactive nanocomposites show great promise in biomedicine for use in tissue growth, wound healing and the potential for bioengineered skin substitutes. Hydrogen-bonded supramolecular polymers (3A-PCL) can be combined with graphite crystals to form graphite/3A-PCL composites with tunable physical properties. When used as a bioactive substrate for cell culture, graphite/3A-PCL composites have an extremely low cytotoxic activity on normal cells and a high structural stability in a medium with red blood cells. A series of in vitro studies demonstrated that the resulting composite substrates can efficiently interact with cell surfaces to promote the adhesion, migration, and proliferation of adherent cells, as well as rapid wound healing ability at the damaged cellular surface. Importantly, placing these substrates under an indirect current electric field at only 0.1 V leads to a marked acceleration in cell growth, a significant increase in total cell numbers, and a remarkable alteration in cell morphology. These results reveal a newly created system with great potential to provide an efficient route for the development of multifunctional bioactive substrates with unique electro-responsiveness to manipulate cell growth and functions. 相似文献
8.
Drinking water quality in the Ethiopian section of the East African Rift Valley I--data and health aspects 总被引:1,自引:0,他引:1
Reimann C Bjorvatn K Frengstad B Melaku Z Tekle-Haimanot R Siewers U 《The Science of the total environment》2003,311(1-3):65-80
Drinking water samples were collected throughout the Ethiopian part of the Rift Valley, separated into water drawn from deep wells (deeper than 60 m), shallow wells (<60 m deep), hot springs (T>36 degrees C), springs (T<32 degrees C) and rivers. A total of 138 samples were analysed for 70 parameters (Ag, Al, As, B, Ba, Be, Bi, Br, Ca, Cd, Ce, Cl, Co, Cr, Cs, Cu, Dy, Er, Eu, F, Fe, Ga, Gd, Ge, Hf, Hg, Ho, I, In, K, La, Li, Lu, Mg, Mn, Mo, Na, Nb, Nd, Ni, NO(2), NO(3), Pb, Pr, Rb, Sb, Se, Si, Sm, Sn, SO(4), Sr, Ta, Tb, Te, Th, Ti, Tl, Tm, U, V, W, Y, Yb, Zn, Zr, temperature, pH, conductivity and alkalinity) with ion chromatography (anions), spectrometry (ICP-OES and ICP-MS, cations) and parameter-specific (e.g. titration) techniques. In terms of European water directives and WHO guidelines, 86% of all wells yield water that fails to pass the quality standards set for drinking water. The most problematic element is fluoride (F), for which 33% of all samples returned values above 1.5 mg/l and up to 11.6 mg/l. The incidence of dental and skeletal fluorosis is well documented in the Rift Valley. Another problematic element may be uranium (U)-47% of all wells yield water with concentrations above the newly suggested WHO maximum acceptable concentration (MAC) of 2 microg/l. Fortunately, only 7% of the collected samples are above the 10 microg/l EU-MAC for As in drinking water. 相似文献
9.
Mathematical model and parallel genetic algorithm for hybrid flexible flowshop lot streaming problem
Fantahun Melaku Defersha Mingyuan Chen 《The International Journal of Advanced Manufacturing Technology》2012,62(1-4):249-265
Lot streaming is the technique of splitting a given job into sublots to allow the overlapping of successive operations in multi-stage manufacturing systems thereby reducing production makespan. Several research articles appeared in literature to solve this problem and most of these studies are limited to pure flowshop environments where there is only a single machine in each stage. On the other hand, because of the applicability of hybrid flowshops in different manufacturing settings, the scheduling of these types of shops is also extensively studied by several authors. However, the issue of lot streaming in hybrid flowshop environment is not well studied. In this paper, we aim to contribute in bridging the gap between the research efforts in flowshop lot streaming and hybrid flowshop scheduling. We propose a mathematical model and a genetic algorithm for the lot streaming problem of several jobs in multi-stage flowshops where at each stage there are unrelated parallel machines. The jobs may skip some of the stages, and therefore, the considered system is a complex generalized flowshop. The proposed genetic algorithm is executed on both sequential and parallel computing platforms. Numerical examples showed that the parallel implementation greatly improved the computational performance of the developed heuristic. 相似文献
10.
Weldemichael Weldeselassie Helen Admassu Emire Shimelis Alemu Melaku 《Food science and biotechnology》2019,28(4):1125-1134
Food Science and Biotechnology - Enset (Ensete ventricosum (Welw.) Cheesman) (false banana) plant is a multipurpose traditional crop widely cultivated in the south and southwestern Ethiopia. A... 相似文献