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Karim Gharbi Louise Matthews James Bron Ron Roberts Alan Tinch Michael Stear 《Journal of the Royal Society Interface》2015,12(110)
Sea lice threaten the welfare of farmed Atlantic salmon and the sustainability of fish farming across the world. Chemical treatments are the major method of control but drug resistance means that alternatives are urgently needed. Selective breeding can be a cheap and effective alternative. Here, we combine experimental trials and diagnostics to provide a practical protocol for quantifying resistance to sea lice. We then combined quantitative genetics with epidemiological modelling to make the first prediction of the response to selection, quantified in terms of reduced need for chemical treatments. We infected over 1400 young fish with Lepeophtheirus salmonis, the most important species in the Northern Hemisphere. Mechanisms of resistance were expressed early in infection. Consequently, the number of lice per fish and the ranking of families were very similar at 7 and 17 days post infection, providing a stable window for assessing susceptibility to infection. The heritability of lice numbers within this time window was moderately high at 0.3, confirming that selective breeding is viable. We combined an epidemiological model of sea lice infection and control on a salmon farm with genetic variation in susceptibility among individuals. We simulated 10 generations of selective breeding and examined the frequency of treatments needed to control infection. Our model predicted that substantially fewer chemical treatments are needed to control lice outbreaks in selected populations and chemical treatment could be unnecessary after 10 generations of selection. Selective breeding for sea lice resistance should reduce the impact of sea lice on fish health and thus substantially improve the sustainability of Atlantic salmon production. 相似文献
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Yingcai Bi Menglu Lan Jiaxin Li Shupeng Lai Ben M. Chen 《Asian journal of control》2019,21(4):1732-1744
Micro Aerial Vehicles (MAVs) have great potentials to be applied for indoor search and rescue missions. In this paper, we propose a modular lightweight design of an autonomous MAV with integrated hardware and software. The MAV is equipped with the 2D laser scanner, camera, mission computer and flight controller, running all the computation onboard in real time. The onboard perception system includes a laser‐based SLAM module and a custom‐designed visual detection module. A dual Kalman filter design provides robust state estimation by multiple sensor fusion. Specifically, the fusion module provides robust altitude measurement in the circumstance of surface changing. In addition, indoor‐outdoor transition is explicitly handled by the fusion module. In order to efficiently navigate through obstacles and adapt to multiple tasks, a task tree‐based mission planning method is seamlessly integrated with path planning and control modules. The MAV is capable of searching and rescuing victims from unknown indoor environments effectively. It was validated by our award‐winning performance at the 2017 International Micro Air Vehicle Competition (IMAV 2017), held in Toulouse, France. The performance video is available on https://youtu.be/8H19ppS_VXM . 相似文献
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The Journal of Supercomputing - Data center network virtualization is being considered as a promising technology to provide a performance guarantee for cloud computing applications. One important... 相似文献
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LNG冷量优化集成利用技术 总被引:7,自引:1,他引:6
我国将相继在沿海地区建成多个LNG接收站,每年将进口数以千万吨计的LNG,同时携带数着巨额冷量,而这些冷量可用于发电、空气分离、制造干冰、低温冷库等众多领域。基于国外LNG冷量利用现状,指出我国即将展开和实施此项技术还存在着:过程火用损较大,缺乏系统、全面的LNG冷量利用技术的研发指导机制,以及宏观调控力度薄弱等问题,进而提出了发展LNG冷量的集成利用方案,可为此类技术的研发利用提供新思路。以福建即将进口的LNG为例,模拟了空气分离与干冰制备的集成工艺流程,结果表明:福建每年进口的260×104t LNG可以冷却290×104t空气,相当于60000 m3/h的氧气制备规模,还可以生产100×104t的干冰,其过程火用损较小;其剩余的高温位冷量可应用于低温冻结库或冰灯等项目,这对主体装置的实施效果和过程火用损的影响较小。该技术的优点在于可灵活控制冷却空气的液化率,基本不用冷却循环水,流程简单,设备投资少,能耗低等。 相似文献
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A therapist's theoretical orientation is likely to influence every facet of the therapeutic process. We explore the relationship of therapeutic orientation and self-monitoring style. To test the hypothesis that high self-monitors would be more eclectic than low self-monitors, we surveyed 30 intake therapists at a child guidance center. Results supported the hypothesis; those frequently using more than one orientation had higher self-monitoring scores. Furthermore, self-monitoring correlated negatively with psychoanalytic endorsement, but in a positive direction with behavioral, systems and eclectic endorsements. Results are discussed in terms of training needs of those differing in self-monitoring style. (PsycINFO Database Record (c) 2010 APA, all rights reserved) 相似文献
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N Haddad R Ben Khelifa H Matter H Kharmachi MF Aubert A Wandeler J Blancou 《Canadian Metallurgical Quarterly》1994,12(4):307-309
The possibility of immunizing dogs orally against rabies, using SADBern, an attenuated strain, was tested on dogs in the field in Tunisia. This strain induced high neutralizing antibody titres and conferred to all vaccinated dogs total resistance against a challenge with a Maghrebian strain. However, an excretion of virus of vaccinal origin was observed in one dog, hampering the use of SADBern in dogs. Nevertheless, this work demonstrates for the first time that dogs in developing countries, especially those which are inaccessible to parenteral vaccination, could be efficiently immunized against rabies by the oral route. 相似文献
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根据延迟焦化流程的特点,分析了延迟焦化装置扩大生产能力的瓶颈,探讨了基于能量综合优化的装置扩能解除瓶颈的策略方法,基于过程能量综合优化,运用流程模拟技术,通过配套的加热炉优化,分馏塔操作优化,换热网络柔性设计等手段,实现了装置扩大生产能力的目的,并运用所提出的策略对某延迟焦化装置进行了基于能量系统优化的扩能改造,在原流程与设备的基础上,装置处理量增大18.2%,装置物耗,能耗大幅度降低,改造设备投资少,说明能量综合优化对工艺装置扩能改造具有重要意义。 相似文献
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