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排序方式: 共有2971条查询结果,搜索用时 15 毫秒
1.
Luc Rochette Loubna Mazini Gabriel Malka Marianne Zeller Yves Cottin Catherine Vergely 《International journal of molecular sciences》2020,21(23)
The potential use of stem cell-based therapies for the repair and regeneration of various tissues and organs is a major goal in repair medicine. Stem cells are classified by their potential to differentiate into functional cells. Compared with other sources, adipose-derived stem cells (ADSCs) have the advantage of being abundant and easy to obtain. ADSCs are considered to be tools for replacing, repairing, and regenerating dead or damaged cells. The capacity of ADSCs to maintain their properties depends on the balance of complex signals in their microenvironment. Their properties and the associated outcomes are in part regulated by reactive oxygen species, which mediate the oxidation-reduction state of cells as a secondary messenger. ADSC therapy has demonstrated beneficial effects, suggesting that secreted factors may provide protection. There is evidence that ADSCs secrete a number of cytokines, growth factors, and antioxidant factors into their microenvironment, thus regulating intracellular signaling pathways in neighboring cells. In this review, we introduce the roles of ADSCs in the protection of cells by modulating inflammation and immunity, and we develop their potential therapeutic properties. 相似文献
2.
Wyatt L. Brown Douglas A. Day Harald Stark Demetrios Pagonis Jordan E. Krechmer Xiaoxi Liu Derek J. Price Erin F. Katz Peter F. DeCarlo Catherine G. Masoud Dongyu S. Wang Lea Hildebrandt Ruiz Caleb Arata David M. Lunderberg Allen H. Goldstein Delphine K. Farmer Marina E. Vance Jose L. Jimenez 《Indoor air》2021,31(1):141-155
Understanding the sources and composition of organic aerosol (OA) in indoor environments requires rapid measurements, since many emissions and processes have short timescales. However, real-time molecular-level OA measurements have not been reported indoors. Here, we present quantitative measurements, at a time resolution of five seconds, of molecular ions corresponding to diverse aerosol-phase species, by applying extractive electrospray ionization mass spectrometry (EESI-MS) to indoor air analysis for the first time, as part of the highly instrumented HOMEChem field study. We demonstrate how the complex spectra of EESI-MS are screened in order to extract chemical information and investigate the possibility of interference from gas-phase semivolatile species. During experiments that simulated the Thanksgiving US holiday meal preparation, EESI-MS quantified multiple species, including fatty acids, carbohydrates, siloxanes, and phthalates. Intercomparisons with Aerosol Mass Spectrometer (AMS) and Scanning Mobility Particle Sizer suggest that EESI-MS quantified a large fraction of OA. Comparisons with FIGAERO-CIMS shows similar signal levels and good correlation, with a range of 100 for the relative sensitivities. Comparisons with SV-TAG for phthalates and with SV-TAG and AMS for total siloxanes also show strong correlation. EESI-MS observations can be used with gas-phase measurements to identify co-emitted gas- and aerosol-phase species, and this is demonstrated using complementary gas-phase PTR-MS observations. 相似文献
3.
A spacecraft in a plasma builds up charge on all the dielectric surfaces and interfaces. Once the net charge exceeds the dielectric breakdown of the material, a discharge occurs. One of the more susceptible pieces of equipment is the antenna/receiver system. The radiated E-field may be strong enough to create an ambiguous signal which may be misinterpreted by the system electronics and cause a system malfunction. A technique is developed to monitor the radiated E-field of materials discharging in an electron environment, using vacuum chambers for measuring the material discharges which are made of highly reflective materials. These chambers affect the radiated E-field due to multiple reflections from the walls. The technique developed defines a method for correcting the effects caused by the measurement facilities. The methodology is: monitor the radiated E-field with a broadband dipole antenna, and digitize the radiated signal as a function of time. Determine the frequency response of the radiated E-field using an FFT algorithm. Measure the transmission and reflection characteristics of the two-port network inside the measurement chamber, and determine the impedance network from the measured E-parameters across the frequency band of interest. Transform the measured E-field frequency response through the impedance network to obtain the frequency response of the actual radiated discharge current. Find the inverse FFT of this response to obtain the actual radiated discharge current response. This technique aids in the prediction of the E-field coupling into receive antennas on-board actual satellites 相似文献
4.
A therapist's theoretical orientation is likely to influence every facet of the therapeutic process. We explore the relationship of therapeutic orientation and self-monitoring style. To test the hypothesis that high self-monitors would be more eclectic than low self-monitors, we surveyed 30 intake therapists at a child guidance center. Results supported the hypothesis; those frequently using more than one orientation had higher self-monitoring scores. Furthermore, self-monitoring correlated negatively with psychoanalytic endorsement, but in a positive direction with behavioral, systems and eclectic endorsements. Results are discussed in terms of training needs of those differing in self-monitoring style. (PsycINFO Database Record (c) 2010 APA, all rights reserved) 相似文献
5.
Jean-Louis Havet Myriam Billiau-Loreau Catherine Porte Alain Delacroix 《Journal of Automated Methods and Management in Chemistry》2002,24(4):111-119
Chemometric tools were used to generate the modelling of solvent e inverted exclamation markects on the N-alkylation of an isocyanuric acid salt. The method proceeded from a central composite design applied on the Carlson solvent classification using principal components analysis. The selectivity of the reaction was studied from the production of different substituted isocyanuric derivatives. Response graphs were obtained for each compound and used to devise a strategy for solvent selection. The prediction models were validated and used to search for the best selectivity for the reaction system. The solvent most often selected as the best for the reaction is the N,N-dimethylformamide. 相似文献
6.
Hinshaw Stephen P.; Carte Estol T.; Fan Catherine; Jassy Jonathan S.; Owens Elizabeth B. 《Canadian Metallurgical Quarterly》2007,21(2):263
The current study prospectively followed girls with attention-deficit/hyperactivity disorder (ADHD), along with a matched comparison sample, 5 years after childhood neuropsychological assessments. Follow-up neuropsychological measures emphasized attentional skills, executive functions, and language abilities. Paralleling childhood findings, the childhood-diagnosed ADHD group displayed moderate to large deficits in executive/attentional performance as well as in rapid naming relative to the comparison group at follow up (Mage 14.2 years). ADHD-inattentive versus ADHD-combined contrasts were nonsignificant and of negligible effect size, even when a refined, sluggish cognitive tempo subgroup of the inattentive type was examined. Although ADHD versus comparison group differences largely withstood statistical control of baseline demographics and comorbidities, control of childhood IQ reduced executive function differences to nonsignificance. Yet when the subset of girls meeting diagnostic criteria for ADHD in adolescence was compared with the remainder of the participants, neuropsychological deficits emerged even with full statistical control. Overall, childhood ADHD in girls portends neuropsychological and executive deficits that persist for at least 5 years. (PsycINFO Database Record (c) 2010 APA, all rights reserved) 相似文献
7.
Catherine J. Harrison Yann A. Le Gouellec Robert C. Cheng Amy E. Childress 《Canadian Metallurgical Quarterly》2007,133(11):1004-1014
A dual-staged nanofiltration process is being evaluated as an alternative to reverse osmosis for seawater desalination. The primary goal of this system is to reduce energy consumption while producing potable water at an acceptable recovery rate. Investigation of this system at the bench-scale level focused on membrane surface characterization, ion rejection (including boron, bromide, and iodide rejection), and flux decline. Results from this study showed that two commercially available nanofiltration membranes can effectively desalinate seawater. Although fouling was apparent—and resulted in approximately 20% flux decline over 3 days—a critical flux was not identifiable. Operation of the system at different cross-flow velocities revealed the significance of hydrodynamic conditions on the polarization modulus, and hence on membrane performance. 相似文献
8.
Andr Hamwi Catherine Latouche B atrice Burteaux Jacques Dupuis 《Fullerenes, Nanotubes and Carbon Nanostructures》1996,4(6):1213-1226
Reaction of metallic fluorides: WF6 TaF5, NbF5 and TiF4 with C60/C70 extract was performed at appropriate temperatures. M0F5 and BF3 fluorides do not react. Chemical formulas based on mass uptake show MFn/C60 ratios up to 2.00. Compounds were analysed by means of X-ray diffraction, FT-IR and NMR spectroscopies. The presence of neutral fluorides and associated anionic species is put forward and it is shown that MFn compounds do not act as fluorination agents. Electrical conductivity measurements are also presented. 相似文献
9.
Catherine Mongenet 《International journal of parallel programming》1997,25(6):497-524
This paper introduces results on placement and communications minimization for systems of affine recurrence equations. We show how to classify the dependences according to the number and nature of communications they may result in. We give both communication-free conditions and conditions for an efficient use of broadcast or neighbor-to-neighbor communication primitives. Since the dependences of a problem can generally not be all communication-free, we finally introduce a heuristic to globally minimize the communications based on the classification of dependences. 相似文献
10.