Heavy metal content of the hair of children in industrial cities

Nuchal screening has the following advantages: Non invasive. First trimester procedure. Results are obtained quickly. 80-90% detection rate for Down's Syndrome.     

Accessory artificial circulation in complex treatment of experimental acute toxic pulmonary edema

In experiments on 50 dogs with toxic acute edema of the lung, induced with intravenous injection of 0.1% silver nitrate, the authors have studied the efficacy of accessory artificial circulation and "conservative" therapy. During the perfusion a discharge of the right portions, adequate extracorporeal gas metabolism, normalization of blood gas and acid-base balance were noted; an intensity of pulmonary edema is descreased. An intensive therapy for pulmonary edema was found to be more effective in association of "conservative" treatment with venoarterial perfusion and blood oxygenation.     

Bacillary generalized angiomatosis in HIV infection

A unique case of generalized bacillary angiomatosis (BA) in a patient who died of HIV infection is described. Apart from widely spread skin lesions there were also manifestations in the brain, lungs, heart, esophagus and intestine. Gram-negative bacteria were found in the histological sections. Oval and roundish bacteria with a predominantly perivascular location were found electron microscopically in the archives material.     

The current course and treatment of infectious endocarditis

Clinical study of 172 patients treated in the Burdenko Military Hospital for subacute infectious endocarditis in 1980-1996 compared with 192 cases in 1950-1979. Contemporary course of the disease is attended by a few symptoms, primordiality and single-valve affection. On the grounds of antibiotics sensitivity of the most prevalent infection agents discovered in 1996, the article develops some schemes of antibacterial therapy for Streptococcus, Enterococcus and staphylococcal etiology of disease. Rational antibiotic therapy together with surgery measures reduced lethality to 14.3% for Streptococcus endocarditis, to 16.7%--for Enterococcus and to 34.4%--for Staphylococcus.     

The possibility of preserving the causative agent of plague in soil in resting (nonculturable) form

The purpose of this study was to find criteria characteristic for patients in need of care and social services. The criteria should serve as a guideline for patients and staff to facilitate care planning before discharge. The sample consisted of 49 patients, born before 1925, in need of emergency inpatient treatment, admitted to medical- or orthopaedic wards. Data of the patient's self care needs were collected by interviews, assessment of self care status and need of treatment. The patients could be divided into three groups depending on type of discharge. Group A (n = 27) discharged home, group B (n = 7) discharged to geriatric clinic and group C (n = 15) discharged and in need of further care and social services. Criteria indicating the patients further assistance from the community were in group C (medical- and orthopaedic wards) deficit in daily living activities and locomotion. Group B had an increased need of support from the physiotherapist and the occupational therapist, in locomotion as well as daily living activities The physician's assessment showed that the criteria behind the decision "no further medical treatment appropriate" and "ready for discharge" were not related to medical impairment but to lack of self care, need of care, rehabilitation and social services.     

An improvement in the methods for the microbiological study of the blood from patients with suppurative-septic infections

The new method for microbiological analysis of blood in patients with pyoseptic infections is based on separate inoculations of plasma, erythrocyte mass, and leukocyte layer in nutrient medium providing conditions for growth of a wide spectrum of aerobes and obligate anaerobes. The method in general ensures a more rapid result and permits differentiation between true and false-positive bacteremia and between stages of septic process (bacteremia and septicemia).     

Effects of electromagnetic radiation of various modes on heart activity (in experiments)

On spinal cord frogs and isolated interauricle to a partition of heart in vivo and in vitro influence the MICROWAVES of a radiation in continuous and modulated modes on function of heart (9.3 Hz is investigated; 0.348-0.16 and 0.016 mV/sm2, modulation from 1 up to 100 Hz). A possibility of influence of an electromagnetic exposure on heart frequency and rhythm is revealed. Pointing of heart in vitro by a neutral red resulted in large number of % of experience in a stop of irradiated heart.     

The relationship between the immunological efficacy of a dried meningococcal group-A polysaccharide vaccine and the molecular parameters of the group-A polysaccharide

This work deals with the problem of relationship between the molecular parameters of group A meningococcal polysaccharide and its immunological effectiveness for laboratory animals and humans. The depolymerization of group A polysaccharide contained in the vaccine leads to a decrease in its capacity of inducing the production of hemagglutinating (19S and 7S) and bactericidal IgA antibodies in humans, as well as inducing an increase in the number of cells producing IgA antibodies in the spleen of immunized mice and the appearance of circulating IgA antibodies in their sera. As shown in this investigation, fully developed immune response to group A meningococcal vaccine may be achieved in humans only if the content of group A high-molecular polysaccharide in the vaccine is not less than 70%. Mice have been recommended as an experimental model for the prognostication of the effectiveness of meningococcal polysaccharide vaccines and for their control in the process of manufacture instead of currently used titration of bacteriolysins in the sera of immunized humans.     

Use of heparin-coated "Jo Stent M" in patients with ischemic heart disease: first results

The aim of the present study was to make a clinical and angiographic assessment of early outcomes of the use of heparin-coated new "Jo Stents M". The Study comprised 41 patients who were implanted a heparin-coated new "Jo Stent M". There was an immediate success in 45 (97.6%) of 46 cases, the optimal angiographic and suboptimal (the maximum residual stenosis (13%)) results being achieved in 43 (93.4%) and 2 (4.4%) cases, respectively. The first success of the procedure was 97.8%. Due to acute stent thrombosis, acute occlusion with evolving myocardial infarction occurred in 1 (2.4%) patient. Following the procedure, the mean proportion of the stenotic diameter was (-5.8 +/- 6)%. After the procedure, the minimum stenotic diameter with the mean due diameter of 2.9 +/- 0.5 mm was 3.0 +/- 0.2 mm. The procedure-induced diameter increase was 2.1 +/- 0.5 mm. The total number of lateral branches involved in the stenting area was 11 (100%), 2 (18.2) of them closed after stent implantation. Two branches came into the stenting area in 1 (2.4%) case. At discharge, angina pectoris was absent in 30 (74%) patients. The heparin-coated "Jo Stent M" are effective and safe in treating patients with various clinical and angiographic manifestations of coronary atherosclerotic lesions.