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排序方式: 共有6763条查询结果,搜索用时 15 毫秒
1.
Assuming that the chemical reactions used to synthesize a combinatorial library member are successful, then knowledge of the specific reaction sequence is equivalent to knowing the member's chemical identity. Because the determination of chemical identity is typically not automatable and requires a substantial amount of material, schemes that encode a member's reaction history onto the reaction platform are of value. The primary benefits of encoding are relational nomenclature (all methods) and automated handling (some methods). Encoding methods evaluated to date are spatial, graphical, chemical, spectrometric, electronic, and physical. 相似文献
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OBJECTIVES: To assess that neuromuscular relaxation onset of the adductor pollicis (AP) is related to neuromuscular stimulation rate. To assess that train-of-four (TOF) at 0.05 Hz is a more accurate indicator of optimal tracheal intubation time and conditions, than TOF at 0.08 Hz. STUDY DESIGN: Prospective, comparative, randomized double-blind study. PATIENTS: Forty adults, physical class ASA 1 or 2, undergoing general anaesthesia with tracheal intubation were allocated to two groups (n = 20) according to the sequence of stimulation of the AP: either TOF at 0.05 Hz (test group) or TOF at 0.08 Hz (control group). METHODS: Induction of anaesthesia was achieved with thiopentone, fentanyl and vecuronium (0.1 mg.kg-1). Neuromuscular monitoring was obtained with force displacement transducers attached to each AP. Tracheal intubation was performed once AP muscular response obtained with TOF at 0.05 Hz for test group and TOF at 0.08 Hz for control group was abolished. Results are expressed as mean +/- SEM. Fisher exact test was used for intubation conditions comparison. Curarization time between groups was compared with unpaired Student's t test (P < 0.05 accepted). RESULTS: TOF with 0.05 Hz stimulation significantly increased curarization time: 217 +/- 7 versus 162 +/- 6 s (P < 0.001). Intubation conditions were excellent in 95% and good in 5% of patients in the study group, compared to 15 and 40% in the control group, respectively (P < 0.01) in 45% of the control group patients coughing at intubation occurred. CONCLUSION: Low stimulation rate (TOF at 0.05 Hz) of AP is a reliable technique to determine the appropriate intubation time for patients paralyzed with vecuronium. 相似文献
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Turner S.E. Elder R.B. Jr. Jansen D.S. Kotecki D.E. 《Microwave and Wireless Components Letters, IEEE》2005,15(3):144-146
A 41-GHz 4-b adder-accumulator test circuit implemented in InP double heterojunction bipolar transistor (DHBT) technology using 624 transistors is reported. High clock rates are obtained by combining the logic functions into pipelined latches. The adder-accumulator contains a single-level parallel-gated carry circuit that is used as a step toward reduced power consumption. The carry circuit has a maximum clock frequency of 55 GHz. The accumulator architecture employs modular, pipelined 2-b adders and is cascadable to 2 N-bits. The test circuit includes a 4-b digital to analog converter (DAC) that facilitates demonstration of high-speed operation. 相似文献
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J. H. Elder S. J. D. Prince Y. Hou M. Sizintsev E. Olevskiy 《International Journal of Computer Vision》2007,72(1):47-66
We address the problem of localizing and obtaining high-resolution footage of the people present in a scene. We propose a
biologically-inspired solution combining pre-attentive, low-resolution sensing for detection with shiftable, high-resolution,
attentive sensing for confirmation and further analysis.
The detection problem is made difficult by the unconstrained nature of realistic environments and human behaviour, and the
low resolution of pre-attentive sensing. Analysis of human peripheral vision suggests a solution based on integration of relatively
simple but complementary cues. We develop a Bayesian approach involving layered probabilistic modeling and spatial integration
using a flexible norm that maximizes the statistical power of both dense and sparse cues. We compare the statistical power
of several cues and demonstrate the advantage of cue integration. We evaluate the Bayesian cue integration method for human
detection on a labelled surveillance database and find that it outperforms several competing methods based on conjunctive
combinations of classifiers (e.g., Adaboost). We have developed a real-time version of our pre-attentive human activity sensor
that generates saccadic targets for an attentive foveated vision system. Output from high-resolution attentive detection algorithms
and gaze state parameters are fed back as statistical priors and combined with pre-attentive cues to determine saccadic behaviour.
The result is a closed-loop system that fixates faces over a 130 deg field of view, allowing high-resolution capture of facial
video over a large dynamic scene. 相似文献
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Morganella morganii postoperative endophthalmitis 总被引:1,自引:0,他引:1
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V Kumar PM Carabateas JA Dority WG Earley JP Mallamo C Subramanyam LD Aimone B Ault DL DeHaven Hudkins MS Miller 《Canadian Metallurgical Quarterly》1995,38(10):1826-1830
Replacement of the pyridinium ring of 6,11-ethanobenzo[b]quinolizinium cations with thiazolium (4a and 4b) and N-methylimidazolium (4c and 4d) resulted in equipotent compounds in the [3H]TCP binding assay. The corresponding N-methyl-1,2,4-triazolium analogs were less potent in this assay. The thiazolium derivative 4b, with a Ki = 2.9 nM, is being evaluated as a possible neuroprotective N-methyl-D-aspartic acid (NMDA) antagonist. 相似文献