Analysis of Combined Systems of Two Endoreversible Engines

A single endoreversible engine can operate as a cooler, a true heat engine, a heat pump, or a refrigerator. We investigate how many different modes of operation a combined system of two endoreversible engines may display. Special attention is paid to the independent combined system which neither consumes nor supplies power.     

Searching for adverse drug reactions at the margin of scientific fields

Results are presented of a scientometric analysis focusing on peripheral dynamics in a scientific field. We evaluate different techniques on their appropriateness for detecting relations between aspects that seem to be not of central interest but are important in innovative research. We do so in order to quantify the role that adverse drug reactions can play as trigger points in innovative drug research.Paper presented at the Fourth International Conference on Bibliometrics, Informetrics and Scientometrics in Berlin (Germany), September 11–15, 1993.     

Tagging of η mesons using the pd → 3Heη reaction near threshold

A zero-degree spectrometer for tagging η mesons on the CELSIUS/WASA facility is described, and its characteristics are presented. Tagging of η mesons is performed by detecting ³He ions produced by reaction pd → ³Heη close to the production threshold. The low background level (<2%) is in good agreement with the data obtained earlier on the SATURNE accelerator.     

Heterogeneous Enzyme Mimics Based on Zeolites and Layered Hydroxides

Careful combination of a metal compound,a ligand and an inorganic support material leads to supramolecular catalysts that mimic the structural, organizational and functional aspects of enzyme activity.After discussing essential features of metalloenzyme-catalyzed reactions and coordination chemistry in inorganic hosts, we present examples of supramolecular materials selected from our own work that eventually resulted in useful catalysts for organic transformations in the liquid phase.     

Six Synthesis Methods for Reversible Logic

The (2 ^w )! reversible transformations on w wires, i.e. reversible logic circuits with w inputs and w outputs, together with the action of cascading, form a group, isomorphic to the symmetric group S ₂ ^w . Therefore, we investigate the group S _n as well as one of its subgroups isomorphic to S _n/2 × S _n/2. We then consider the left cosets, the right cosets, and the double cosets generated by the subgroup. Each element of a coset can function as the representative of the coset. The coset can then be considered as the set of all group elements that differ from the representative by merely multiplying (either to the left or to the right or to both sides) by an arbitrary element of the subgroup. Different choices of the coset space and different choices of the coset representatives lead to six different syntheses for implementing an arbitrary reversible logic operation into hardware. Evaluation of all six methods, by means of three different cost functions (gate cost, switch cost, and quantum cost), leads to a best choice.     

Esterification and Transesterification of Renewable Chemicals

An overview is given of newly developed Lewis or Brønsted acid and base catalysts for esterification, transesterification and ester interchange reactions. The most relevant applications of these catalysts and reactions in the domain of renewable resources, in particular, oils and fats, are discussed.     

The development of a glove-box/Vitrobot combination: air-water interface events visualized by cryo-TEM

Aqueous interfaces are of paramount importance in the study of biological systems as well as in the biomedical sciences. To study these interfaces at the nanometer level it is of interest to develop methods that allow their observation with cryogenic transmission electron microscopy (cryo-TEM). Prevention of dehydration to preserve the "native" state during sample preparation prior to vitrification is often one of the most important parameters to control in cryo-TEM experiments. For the preparation of these types of samples, we felt the need for an extended workspace with temperature and humidity control; a 'glove-box' that seamlessly connects to the vitrification instrument, the Vitrobot. In this paper we describe the use of the glove-box in the 2D and 3D cryo-TEM study of DNA adsorption and calcium carbonate mineralization to Langmuir films. The data presented illustrates the necessity of a humidity-controlled environment to preserve the original "native" state of the monolayer system.     

Resource allocation in grid computing

Grid computing, in which a network of computers is integrated to create a very fast virtual computer, is becoming ever more prevalent. Examples include the TeraGrid and Planet-lab.org, as well as applications on the existing Internet that take advantage of unused computing and storage capacity of idle desktop machines, such as Kazaa, SETI@home, Climateprediction.net, and Einstein@home. Grid computing permits a network of computers to act as a very fast virtual computer. With many alternative computers available, each with varying extra capacity, and each of which may connect or disconnect from the grid at any time, it may make sense to send the same task to more than one computer. The application can then use the output of whichever computer finishes the task first. Thus, the important issue of the dynamic assignment of tasks to individual computers is complicated in grid computing by the option of assigning multiple copies of the same task to different computers. We show that under fairly mild and often reasonable conditions, maximizing task replication stochastically maximizes the number of task completions by any time. That is, it is better to do the same task on as many computers as possible, rather than assigning different tasks to individual computers. We show maximal task replication is optimal when tasks have identical size and processing times have a NWU (New Worse than Used; defined later) distribution. Computers may be heterogeneous and their speeds may vary randomly, as is the case in grid computing environments. We also show that maximal task replication, along with a c μ rule, stochastically maximizes the successful task completion process when task processing times are exponential and depend on both the task and computer, and tasks have different probabilities of completing successfully.     

双享空间的幽默合辑

Extract荷兰Den Bosh的一怕老建筑,最近迎来自己的新生。那是座建于20世纪的双层Loft,在设计师Roderick Vos的改造下,它的空间一半被用于零售展示,一半用于办公思考。它模糊了设计师与顾客、艺术与生活的界限,令每一位到访者都能在幽默而单纯的氛围中,领略双享空间的专业设计精神。