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排序方式: 共有198条查询结果,搜索用时 15 毫秒
1.
Hahlweg Kurt; Markman Howard J.; Thurmaier Franz; Engl Jochen; Eckert Volker 《Canadian Metallurgical Quarterly》1998,12(4):543
This article reports on the development and long-term evaluation of a marital distress prevention program for German couples, the Ein Partnerschaftliches Lernprogramm (EPL, A Couple's Learning Program). The EPL is a 6-session program designed to teach couples effective communication and problem-solving skills. In the current article, the EPL is evaluated in a prospective, quasi-experimental, controlled trial. The results of the 3-year follow-up are reported, contrasting 55 EPL couples with a control group of 17 couples. Significant differences emerged with regard to the couples' dissolution rates, relationship satisfaction, and positive and negative communication behavior favoring the EPL couples. These results demonstrate the utility of the EPL program in assisting happy couples who are preparing for marriage. The implications of the findings for prevention research and for the dissemination of prevention programs are discussed. (PsycINFO Database Record (c) 2010 APA, all rights reserved) 相似文献
2.
A technique is described for monitoring and analysis of the angular displacement of the human torso. The technique is based on the use of miniature electromechanical inclinometers and video recording. The system was developed for continuous measurement of the angular displacement of spinal segments in the sagittal plane during all stages of lifting. Angular displacements of the cervical, thoracic and lumbar regions were obtained from a dynamic lifting case study using a digital processing system. The geometrical changes of the torso during five prescribed stages were measured. The system revealed good accuracy with high correlation coefficient scores for a wide range of lifting tasks in a comparative laboratory study. This paper describes the monitoring technique; the system's advantages, disadvantages and measuring accuracy are discussed. 相似文献
3.
We present a new approach to rigid-body motion segmentation from two views. We use a previously developed nonlinear embedding of two-view point correspondences into a 9-dimensional space and identify the different motions by segmenting lower-dimensional subspaces. In order to overcome nonuniform distributions along the subspaces, whose dimensions are unknown, we suggest the novel concept of global dimension and its minimization for clustering subspaces with some theoretical motivation. We propose a fast projected gradient algorithm for minimizing global dimension and thus segmenting motions from 2-views. We develop an outlier detection framework around the proposed method, and we present state-of-the-art results on outlier-free and outlier-corrupted two-view data for segmenting motion. 相似文献
4.
We present a new concept—Wikiometrics—the derivation of metrics and indicators from Wikipedia. Wikipedia provides an accurate representation of the real world due to its size, structure, editing policy and popularity. We demonstrate an innovative “mining” methodology, where different elements of Wikipedia – content, structure, editorial actions and reader reviews – are used to rank items in a manner which is by no means inferior to rankings produced by experts or other methods. We test our proposed method by applying it to two real-world ranking problems: top world universities and academic journals. Our proposed ranking methods were compared to leading and widely accepted benchmarks, and were found to be extremely correlative but with the advantage of the data being publically available. 相似文献
5.
Gilad Nahari Dr. Ori Braitbard Dr. Liraz Larush Prof. Jacob Hochman Prof. Edit Y. Tshuva 《ChemMedChem》2021,16(1):108-112
Abstract : Orally administered anticancer drugs facilitate treatment, but the acidic conditions in the stomach often challenge their availability. PhenolaTi is a TiIV-based nontoxic anticancer drug with marked in-vivo efficacy. We report that nanoformulation protects phenolaTi from decomposition in stomach-like conditions. This is evidenced by similar NMR characteristics and similar in-vitro cytotoxicity toward murine (CT-26) and human (HT-29) colon cancer cells before and after incubation of nanoformulated phenolaTi (phenolaTi-F) at pH 2, unlike results with the unformulated form of the complex. Furthermore, administration of phenolaTi-F in animal drinking water revealed a notable inhibition of tumor growth in Balb/c and immune-deficient (Nude) mice inoculated with CT-26 and HT-29 cells, respectively. In-vivo efficacy was at least similar to that of the corresponding intraperitoneal treatment with phenolaTi-F and the clinically employed oral drug, capecitabine. No body weight loss or clinical signs of toxicity were evident in the phenolaTi-F-treated animals. These findings demonstrate a new convenient mode of cancer treatment through oral administration by safe titanium-based drugs. 相似文献
6.
The problem of carrying out cryptographic computations when the participating parties are rational in a game-theoretic sense has recently gained much attention. One problem that has been studied considerably is that of rational
secret sharing. In this setting, the aim is to construct a mechanism (protocol) so that parties behaving rationally have incentive
to cooperate and provide their shares in the reconstruction phase, even if each party prefers to be the only one to learn
the secret. 相似文献
7.
A transient increase in brain polyamine metabolism, termed the polyamine-stress-response is a common response to stressful stimuli. Previous studies have implicated an over-reactive polyamine response as a component of the maladaptive brain response to stressful events, and as a novel molecular mechanism involved in the pathophysiology of affective disorders. Ample evidence indicates that stressful experiences during early life can alter normal developmental processes and may result in pathophysiological and behavioral changes in the adult. Additionally, an important characteristic of affective disorders is their age dependency, a phenomenon that may be correlated with a maladaptive regulation of the hypothalamic-pituitary-adrenocortical (HPA) neuroendocrine system. In the present study we measured the activities of the enzymes ornithine decarboxylase and S-adenosylmethionine decarboxylase as markers of polyamine synthesis and found that unlike adults, immature rats do not show the characteristic brain polyamine-stress-response. Instead of the characteristic increase observed in adults, ornithine decarboxylase activity in immature animals was reduced or remained unchanged (for up to 16 days of age) after a dexamethasone injection or restraint stress application. The ontogenesis of this ornithine decarboxylase response was brain region-specific, indicating its dependence on the stage of neuronal maturation. Animals treated with dexamethasone at 7 days of age, showed increased behavioral reactivity in the open-field test as adults and an attenuated increase in ornithine decarboxylase activity after a re-challenge with dexamethasone at age 60 days. The results indicate that: (1) the brain polyamine-stress-response is developmentally regulated and its ontogenesis is brain region-specific, indicating dependence on the stage of neuronal maturation; (2) the switch to a mature polyamine-stress-response pattern coincides with the cessation of the stress hyporesponsive period in the HPA system: (3) activation of the polyamine-stress-response, as in the mature brain, appears to be a constructive reaction, while its down-regulation, as in the developing brain, may be implicated in neuronal cell death; (4) an attenuated dexamethasone-induced increase in ornithine decarboxylase activity implicates an altered polyamine-stress-response in the maladaptive response of the brain to stressful events. 相似文献
8.
9.
Lactide-based low molecular weight copolymers were synthesized and investigated as tissue adhesives. The oligomers were composed of di or trifunctional central connecting segments and lateral PLA blocks. Copolymers with glass transition temperatures in the 20–25 °C range, were found to perform better. Strong connection was found between the length of the PLA blocks, the glass transition temperature (T
g) and the Adhesive Failure Strength of the different materials. Flexible -caprolactone (CL) molecules were inserted into the PLA blocks, to produce longer biodegradable chains and improve the adhesive strength of the oligomers, while keeping their T
g within the appropriate temperature interval. Branched oligomers consisting of a trimethylolpropane central molecule and three LA–CL segments, displayed enhanced in vitro adhesive properties. 相似文献
10.
Arthur B. Markman Jennifer S. Beer Lisa R. Grimm Jonathan R. Rein W. Todd Maddox 《人工智能实验与理论杂志》2013,25(3):197-215
Cognitive science research is hard to conduct, because researchers must take phenomena from the world and turn them into laboratory tasks for which a reasonable level of experimental control can be achieved. Consequently, research necessarily makes tradeoffs between internal validity (experimental control) and external validity (the degree to which a task represents behaviour outside of the lab). Researchers are thus seeking the best possible trade-off between these constraints, which we refer to as the optimal level of fuzz. We present two principles for finding the optimal level of fuzz, in research, and then illustrate these principles using research from motivation, individual differences and cognitive neuroscience. 相似文献