全文获取类型
收费全文 | 334篇 |
免费 | 24篇 |
专业分类
电工技术 | 2篇 |
化学工业 | 100篇 |
机械仪表 | 1篇 |
建筑科学 | 12篇 |
能源动力 | 15篇 |
轻工业 | 104篇 |
水利工程 | 4篇 |
石油天然气 | 2篇 |
无线电 | 13篇 |
一般工业技术 | 34篇 |
冶金工业 | 9篇 |
原子能技术 | 2篇 |
自动化技术 | 60篇 |
出版年
2023年 | 1篇 |
2022年 | 18篇 |
2021年 | 18篇 |
2020年 | 1篇 |
2019年 | 6篇 |
2018年 | 8篇 |
2017年 | 10篇 |
2016年 | 10篇 |
2015年 | 12篇 |
2014年 | 18篇 |
2013年 | 27篇 |
2012年 | 23篇 |
2011年 | 36篇 |
2010年 | 22篇 |
2009年 | 31篇 |
2008年 | 21篇 |
2007年 | 15篇 |
2006年 | 8篇 |
2005年 | 13篇 |
2004年 | 10篇 |
2003年 | 16篇 |
2002年 | 11篇 |
2000年 | 2篇 |
1999年 | 1篇 |
1998年 | 4篇 |
1997年 | 3篇 |
1996年 | 1篇 |
1995年 | 2篇 |
1994年 | 1篇 |
1989年 | 2篇 |
1987年 | 1篇 |
1986年 | 2篇 |
1985年 | 3篇 |
1976年 | 1篇 |
排序方式: 共有358条查询结果,搜索用时 32 毫秒
1.
Rodríguez-Pérez Ángel Mariano Pérez-Calañas Cinta Pulido-Calvo Inmaculada 《Water Resources Management》2021,35(6):1977-1990
Water Resources Management - This paper aims to evaluate the possibility of using non-utilized hydraulic energy in urban water distribution systems. For this purpose, the viability and possible... 相似文献
2.
This paper explores current applications for handheld devices and questions which of these make full use of the unique attributes of handheld devices in order to facilitate learning in a pedagogically sensible manner. In order to do so, the paper presents a functional framework which analyses handheld application in relation to their use as well as the pedagogical underpinning, if any, that informs their development. Our framework currently consists of seven distinct categories of application, which we term: administrative, referential, interactive, microworld, data collection, location aware and collaborative. We argue that three categories, namely data collection, location aware and collaborative, are particularly suited to learning with handheld devices when they are informed by collaborative, contextual and constructionist learning theories. Furthermore, we contend that applications of the type just outlined deserve further research since they are not attempting to replicate, or even augment, existing learning scenarios but rather they try to create new learning opportunities which would not be possible without (mobile) technology. Finally, the authors introduce a number of applications and learning scenarios that they have developed for handheld devices and explain their position within the framework. 相似文献
3.
Sara da Mata Joana Ferreira Inmaculada Nicols Susana Esteves Gonalo Esteves Sofia Lrias Fernanda Silva Adela Saco Daniela Cochicho Mrio Cunha Marta del Pino Jaume Ordi Ana Flix 《International journal of molecular sciences》2021,22(5)
The expression of p16 is a good surrogate of human papillomavirus (HPV) infection in HPV-associated cancers. The significance of p16 expression, HPV genotype and genera in the outcome of patients with HPV-associated cervical cancer (CC) is unclear. Our aim is to ascertain the prognostic significance of these factors. Data from 348 patients (median age: 47.5 years old) with CC, diagnosed in two referral centers, were retrospectively collected. Advanced disease (FIGO2018 IB2-IV) was present in 68% of patients. A single HPV genotype was identified in 82.8% of patients. The most common HPVs were HPV16 (69%) and HPV18 (14%). HPV genera reflected this distribution. HPV16 tumors presented at an earlier stage. P16 was negative in 18 cases (5.2%), 83.3% of which were squamous cell carcinomas. These cases occurred in older patients who tended to have advanced disease. In the univariate analysis, HPV16 (HR: 0.58; p = 0.0198), α-9 genera (HR: 0.37; p = 0.0106) and p16 overexpression (HR: 0.54; p = 0.032) were associated with better survival. HPV16 (HR: 0.63; p = 0.0174) and α-9 genera (HR: 0.57; p = 0.0286) were associated with less relapse. In the multivariate analysis, only the International Federation of Gynecology and Obstetrics (FIGO) stage retained an independent prognostic value. HPV16, α-9 genera and p16 overexpression were associated with better survival, although not as independent prognostic factors. Patients with p16-negative HPV-associated CC were older, presented with advanced disease and had worse prognosis. 相似文献
4.
Boraldi F Annovi G Guerra D Paolinelli Devincenzi C Garcia-Fernandez MI Panico F De Santis G Tiozzo R Ronchetti I Quaglino D 《Proteomics. Clinical applications》2009,3(9):1084-1098
Pseudoxanthoma elasticum (PXE) is a genetic disorder associated to mutations in the ABCC6 gene; however, the pathogenetic mechanisms leading to elastic fibre calcifications and to clinical manifestations are still unknown. Dermal fibroblasts, directly involved in the production of the extracellular milieu, have been isolated from healthy subjects and from patients affected by PXE, cultured in vitro and characterized for their ability to produce reactive oxygen species, for structural and functional properties of their cell membranes, for changes in their protein profile. Data demonstrate that oxidative stress has profound and endurable consequences on PXE fibroblast phenotype being responsible for: reduced levels of global DNA methylation, increased amount of carbonylated proteins and of lipid peroxidation products, altered structural properties of cell membranes, modified protein expression. Data shed new light on the pathogenetic pathways in PXE, by identifying a network of proteins affecting elastic fibre calcification through inefficient vitamin K recycling, and highlight the role of differentially expressed proteins as targets for validating the efficacy of future therapeutic strategies aiming to delay and/or revert the pathologic phenotype of PXE fibroblasts. Moreover, data open new perspectives for investigating PXE-like phenotypes in the absence of ABCC6 mutations. 相似文献
5.
6.
Inmaculada Higueras 《Journal of scientific computing》2009,39(1):115-128
Space discretization of some time dependent partial differential equations give rise to ordinary differential equations containing
additive terms with different stiffness properties. In these situations, additive Runge-Kutta (additive RK) methods are used.
For additive RK methods the curve of absolute monotonicity gives stepsize restrictions for monotonicity. Necessary conditions
for nontrivial curves of absolute monotonicity are the nonnegativity of the additive RK coefficients and some inequalities
on some incidence matrices. In this paper we characterize strong stability preserving additive Runge-Kutta methods giving
some order barriers and structural properties.
Research supported by the Ministerio de Educación y Ciencia, Project MTM2005-03894. 相似文献
7.
Sergio Martin Gabriel Diaz Inmaculada Plaza Elena Ruiz Manuel Castro Juan PeireAuthor vitae 《Journal of Systems and Software》2011,84(11):1883-1891
The emergence of mobile and ubiquitous technologies as important tools to complement formal learning has been accompanied by a growing interest in their educational benefits and applications. Mobile devices can be used to promote learning anywhere and anytime, to foster social learning and knowledge sharing, or to visualize augmented reality applications for learning purposes. However, the development of these applications is difficult for many researchers because it requires understanding many different protocols; dealing with distributed schemas, processes, platforms, and services; learning new programming languages; and interacting with different hardware sensors and drivers. For that reason, the use of frameworks and middleware that encapsulate part of this complexity appears to be fundamental to the further development of mobile learning projects. This study analyzes the state of the art of frameworks and middleware devoted to simplifying the development of mobile and ubiquitous learning applications. The results can be useful to many researchers involved in the development of projects using these technologies by providing an overview of the features implemented in each of these frameworks. 相似文献
8.
Prediction of parking space availability in real time 总被引:1,自引:0,他引:1
Intelligent parking reservation (IPR) systems allow customers to select a parking facility according to their preferences, rapidly park their vehicle without searching for a free stall, and pay their reservation in advance avoiding queues. Some IPR systems interact with in-vehicle navigation systems and provide users with information in real time such as capacity, parking fee, and current parking utilization. However, few of these systems provide information on the forecast utilization at specific hours - a process that requires the study of the competition between parking alternatives for the market share. This paper proposes a methodology for predicting real-time parking space availability in IPR architectures. This methodology consists of three subroutines to allocate simulated parking requests, estimate future departures, and forecast parking availability. Parking requests are allocated iteratively using an aggregated approach as a function of simulated drivers’ preferences, and parking availability. This approach is based on a calibrated discrete choice model for selecting parking alternatives. A numerical comparison between a one-by-one simulation-based forecast and the proposed aggregated approach indicates that no significant discrepancies exists, validating and suggesting the use of the less time consuming proposed aggregated methodology. Results obtained from contrasting predictions with real data yielded small average error availabilities. The forecast improves as the system registers arrivals and departures. Thus, the forecast is adequate for potential distribution in real-time using different media such as Internet, navigation systems, cell phones or GIS. 相似文献
9.
Cristina Soguero-Ruiz Francisco-Javier Gimeno-Blanes Inmaculada Mora-Jiménez María Pilar Martínez-Ruiz José-Luis Rojo-Álvarez 《Expert systems with applications》2012,39(17):12784-12798
The assessment of promotional sales with models constructed by machine learning techniques is arousing interest due, among other reasons, to the current economic situation leading to a more complex environment of simultaneous and concurrent promotional activities. An operative model diagnosis procedure was previously proposed in the companion paper, which can be readily used both for agile decision making on the architecture and implementation details of the machine learning algorithms, and for differential benchmarking among models. In this paper, a detailed example of model analysis is presented for two representative databases with different promotional behaviour, namely, a non-seasonal category (milk) and a heavily seasonal category (beer). The performance of four well-known machine learning techniques with increasing complexity is analyzed in detail here. In particular, k-Nearest Neighbours, General Regression Neural Networks, Multilayer Perceptron (MLP), and Support Vector Machines (SVM), are differentially compared. Present paper evaluates these techniques along the experiments described for both categories when applying the methodological findings obtained in the companion paper. We conclude that some elements included in the architecture are not essential for a good performance of the machine learning promotional models, such as the semiparametric nature of the kernel in SVM models, whereas other can be strongly dependent of the database, such as the convenience of multiple output models in MLP regression schemes. Additionally, the specificity of the behaviour of certain categories and product ranges determines the need to establish suitable and specific procedures for a better prediction and feature extraction. 相似文献
10.
The effects of dietary inclusion of freeze-dried goat and cow milk on the utilization of zinc and selenium, and on the metabolic fate of zinc, were studied in transected (control) and resected rats (resection of 50% of the distal small intestine). Intestinal resection reduced the apparent digestibility coefficient and zinc retention in the cow milk diet, whereas these biological indices were similar in transected (control) and resected rats with standard (without milk) and goat milk diets. The apparent digestibility coefficient and retention of selenium were not affected by intestinal resection in the animals fed with the three diets studied. In transected (control) and resected rats, the apparent digestibility coefficient and retention of zinc and selenium were higher for the goat milk diet than for the other two diets. Zinc deposits in the organs, expressed as microg/g dry weight were in order of decreasing concentrations: femur, testes, sternum, liver, kidney, heart, spleen, longissimus dorsi muscle and brain. Deposits were greatest with the goat milk diet, followed by the standard diet and were lowest for the rats given the cow milk diet, both for transected (control) and resected animals. We conclude that consumption of the goat milk diet produces a greater bioavailability of zinc and selenium and a greater deposit of zinc in key organs, for both the transected (control) and the resected rats, with respect to the standard diet and the cow milk diet. 相似文献