Task versus relationship conflict, team performance, and team member satisfaction: A meta-analysis.

This study provides a meta-analysis of research on the associations between relationship conflict, task conflict, team performance, and team member satisfaction. Consistent with past theorizing, results revealed strong and negative correlations between relationship conflict, team performance, and team member satisfaction. In contrast to what has been suggested in both academic research and introductory textbooks, however, results also revealed strong and negative (instead of the predicted positive) correlations between task conflict, team performance, and team member satisfaction. As predicted, conflict had stronger negative relations with team performance in highly complex (decision making, project, mixed) than in less complex (production) tasks. Finally, task conflict was less negatively related to team performance when task conflict and relationship conflict were weakly, rather than strongly, correlated. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

诱惑系统架构师与电源供应商的数字电源技术

数字电源指望通过改善维护成本和可靠性、降低电源元件成本、简化BOM来降低系统电源总成本。设计者必须为传统的笨拙电源子系统增加智能。数字电源控制与管理IC有助于这些目标的实现。     

数字放大器—3G无线基站的助推器

为了构筑第三代无线网络,人们需要对现有基础设施进行彻底改造,包括网络的发射基站。配置在无线基站中的新型数字控制功率放大器能够改善频谱利用率和功率效率,从而提高系统容量。PMC-Sierra公司的数字控制功率放大器采用了数字校正信号处理器(DCSP)以及自适应控制处理器和补偿估值器(ACPCE),该放大器可改善无线基础设施的可靠性,同时降低系统成本、规模及复杂性。     

Effect of trichloroethylene on the exploratory and locomotor activity of rats exposed during development

Trichloroethylene (TCE) is a common contaminant of underground water supplies. To examine the effect of TCE on the developing central nervous system, rats were exposed to TCE throughout gestation until 21 days postpartum via their dams' drinking water. TCE concentrations of 312 mg/l, 625 mg/l and 1250 mg/l were tested. Exploratory behavior was higher in 60- and 90-day old male rats which were exposed to any level of TCE. The effect of TCE-exposure on locomotor activity (running wheel) was also examined in 60-day old males (625 and 1250 ppm exposure groups). Locomotor activity was significantly higher in rats exposed to 1250 ppm TCE. These data suggest that TCE has long-term effects on behaviour.     

采用网状网络技术构建一个无线世界

目前的第一代无线局域网(WLAN)仅仅用来简单地取代有线,即只是用来消除主要家庭娱乐系统或办公设备部署采用过多线缆所引起的混乱.而实际上,无线通信的优势远远不止这一点.摆脱线缆的束缚之后,设备间可能的连接方式将大量增加.     

Recognizing, assessing, and intervening with problems of professional competence.

Working collaboratively, psychologist educators and trainers at the doctoral, internship, and postdoctoral levels; credentialers; practitioners; and students offer 8 proposals for psychologists to consider in recognizing, assessing, and intervening with problems of professional competence in students and practicing professionals. In the proposals, the authors address the following topics: definitions and categories; preparing the system; self-assessment; remediation; diversity; communication across various levels of the system; confidentiality; and ethical, regulatory, and legal underpinnings. They also propose future directions for the assessment of problems in professional competence in both students and practicing psychologists. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Substance use escalation and substance use restraint among adolescent children of alcoholics.

Assessed the escalations in substance use over 3 yrs among 246 adolescent children of alcoholics (COAs) and 208 controls (aged 10.5–15.5 yrs). Older COAs showed the steepest escalations in drug use. Younger COAs whose fathers had continuing alcohol-related consequences showed the greatest escalations in alcohol use. Ss' beliefs about drinking restraint were related to their alcohol and drug use. Those whose alcoholic fathers had no continuing alcohol-related consequences showed the strongest relations between substance use and self-control reasons for limiting drinking, perceived risk for future drug problems, and seeing the negative effects of alcohol on someone else. These adolescents may be deterred from substance use escalations because of particular parental characteristics (e.g., mild forms of paternal alcoholism) or because of their beliefs about substance use. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Hepatic toxicity associated with fluorouracil plus levamisole adjuvant therapy

PURPOSE: To determine the frequency and nature of hepatic toxicity associated with fluorouracil (5-FU) plus levamisole adjuvant therapy. PATIENTS AND METHODS: All patients had resection of stage II or stage III colon cancer and were randomized to receive observation only, levamisole alone, or 5-FU plus levamisole. Serial liver function studies were documented in 1,025 patients who did not develop recurrence during the year of therapy. RESULTS: One hundred forty-nine (39.6%) of 376 patients treated with 5-FU plus levamisole showed laboratory abnormalities consistent with hepatic toxicity, compared with 16.3% of 251 patients treated with levamisole alone and 16.1% of 398 untreated controls. Most common was elevation of alkaline phosphatase, frequently accompanied by elevations of transaminase or serum bilirubin. Characteristically, these changes were mild, not associated with symptoms, and resolved when therapy was stopped. In some instances, they were associated with elevated carcinoembryonic antigen (CEA) tests or with fatty liver seen on computed tomographic (CT) scan or liver biopsy. CONCLUSION: Mild and reversible hepatotoxicity is a common consequence of 5-FU plus levamisole adjuvant therapy, but this is only rarely symptomatic. However, the oncologist should be alert to this phenomenon, since the associated laboratory and imaging findings may simulate those associated with hepatic metastasis.     

rab3 mediates cortical granule exocytosis in the sea urchin egg

Egg activation at fertilization in the sea urchin results in the exocytosis of approximately 15,000 cortical granules that are docked at the plasma membrane. Previously, we reported that several integral membrane proteins modeled in the SNARE hypothesis, synaptotagmin, VAMP, and syntaxin, in addition to a small GTPase of the ras superfamily, rab3, were present on cortical granules (Conner, S., Leaf, D., and Wessel, G., Mol. Reprod. Dev. 48, 1-13, 1997). Here we report that rab3 is associated with cortical granules throughout oogenesis, during cortical granule translocation, and while docked at the egg plasma membrane. Following cortical granule exocytosis, however, rab3 reassociates with a different population of vesicles, at least some of which are of endocytic origin. Because of its selective association with cortical granules in eggs and oocytes, we hypothesize that rab3 functions in cortical granule exocytosis. To test this hypothesis, we used a strategy of interfering with rab3 function by peptide competition with its effector domain, a conserved region within specific rab types. We first identified the effector domain sequence in Lytechinus variegatus eggs and find the sequence 94% identical to the effector domain of rab3 in Stronglocentrotus purpuratus. Then, with synthetic peptides to different regions of the rab3 protein, we find that cortical granule exocytosis is inhibited in eggs injected with effector domain peptides, but not with peptides from the hypervariable region or with a scrambled effector peptide. Additionally, effector-peptide-injected eggs injected with IP3 are blocked in their ability to exocytose cortical granules, suggesting that the inhibition is directly on the membrane fusion event and not the result of interference with the signal transduction mechanism leading to calcium release. We interpret these results to mean that rab3 functions in the regulation of cortical granule exocytosis following vesicle docking.