全文获取类型
收费全文 | 699篇 |
免费 | 26篇 |
专业分类
电工技术 | 6篇 |
综合类 | 3篇 |
化学工业 | 131篇 |
金属工艺 | 8篇 |
机械仪表 | 21篇 |
建筑科学 | 18篇 |
能源动力 | 27篇 |
轻工业 | 139篇 |
水利工程 | 2篇 |
石油天然气 | 6篇 |
无线电 | 70篇 |
一般工业技术 | 73篇 |
冶金工业 | 133篇 |
原子能技术 | 1篇 |
自动化技术 | 87篇 |
出版年
2023年 | 9篇 |
2022年 | 14篇 |
2021年 | 26篇 |
2020年 | 16篇 |
2019年 | 13篇 |
2018年 | 16篇 |
2017年 | 27篇 |
2016年 | 19篇 |
2015年 | 15篇 |
2014年 | 15篇 |
2013年 | 37篇 |
2012年 | 20篇 |
2011年 | 27篇 |
2010年 | 29篇 |
2009年 | 42篇 |
2008年 | 24篇 |
2007年 | 35篇 |
2006年 | 23篇 |
2005年 | 14篇 |
2004年 | 23篇 |
2003年 | 15篇 |
2002年 | 11篇 |
2001年 | 15篇 |
2000年 | 14篇 |
1999年 | 11篇 |
1998年 | 31篇 |
1997年 | 18篇 |
1996年 | 25篇 |
1995年 | 18篇 |
1994年 | 11篇 |
1993年 | 11篇 |
1992年 | 9篇 |
1991年 | 15篇 |
1990年 | 7篇 |
1989年 | 5篇 |
1988年 | 4篇 |
1987年 | 5篇 |
1986年 | 5篇 |
1985年 | 4篇 |
1984年 | 5篇 |
1982年 | 2篇 |
1981年 | 2篇 |
1980年 | 3篇 |
1979年 | 4篇 |
1978年 | 7篇 |
1977年 | 2篇 |
1976年 | 6篇 |
1975年 | 2篇 |
1974年 | 2篇 |
1972年 | 2篇 |
排序方式: 共有725条查询结果,搜索用时 15 毫秒
1.
2.
3.
Brefeldin A (BFA) has been reported to cause disassembly of the Golgi. We have used three-dimensional (3-D) high-resolution scanning electron microscopy (HRSEM) to investigate these effects in human skin fibroblast cells. The spontaneous reassembly during prolonged exposure to BFA and some effects of forskolin were observed. A BFA concentration of 5μg/ml caused Golgi complexes to become vesicular, resulting in a progressive decrease in the size of the Golgi. Morphologic changes were visible within 2 min of BFA incubation, and by 30 min no identifiable Golgi could be found. Spontaneous reassembly of the Golgi apparatus upon the removal of the BFA or with continued long-term exposure with BFA could not be confirmed. Preliminary experiments with forskolin were not effective in reversing or inhibiting the effects of BFA in human fibroblast cells grown in culture. This inability for spontaneous reassembly and nonreversal by forskolin may reflect a differential effect of BFA in various cell types. HRSEM has proven to be useful for observing 3-D morphologic effects of BFA in Golgi. 相似文献
4.
JA Tumlin JP Lea CE Swanson CL Smith SS Edge JS Someren 《Canadian Metallurgical Quarterly》1997,99(6):1217-1223
1. PD 81,723 has been shown to enhance binding of adenosine to A1 receptors by stabilizing G protein-receptor coupling ('allosteric enhancement'). Evidence has been provided that in the perfused hearts and isolated atria PD 81,723 causes a sensitization to adenosine via this mechanism. 2. We have studied the effect of PD 81,723 in guinea-pig isolated atrial myocytes by use of whole-cell measurement of the muscarinic K+ current (I[K(ACh)]) activated by different Gi-coupled receptors (A1, M2, sphingolipid). PD 81,273 caused inhibition of I[K(ACh)] (IC50 approximately 5 microM) activated by either of the three receptors. Receptor-independent I[K(ACh)] in cells loaded with GTP-gamma-S and background I[K(ACh)], which contributes to the resting conductance of atrial myocytes, were equally sensitive to PD 81,723. At no combination of concentrations of adenosine and PD 81,723 could an enhancing effect be detected. 3. The compound was active from the outside only. Loading of the cells with PD 81,723 (50 microM) via the patch pipette did not affect either I[K(ACh)] or its sensitivity to adenosine. We suggest that PD 81,723 acts as an inhibitor of inward rectifying K+ channels; this is supported by the finding that ventricular I(K1), which shares a large degree of homology with the proteins (GIRK1/GIRK4) forming I[K(ACh)] but is not G protein-gated, was also blocked by this compound. 4. It is concluded that the functional effects of PD 81,723 described in the literature are not mediated by the A1 adenosine receptor-Gi-I[K(ACh)] pathway. 相似文献
5.
R.D. Toledo Filho J.P. Gonçalves E.M.R. Fairbairn 《Cement and Concrete Research》2007,37(9):1357-1365
The Brazilian ceramic industry generates large amounts of calcined-clay waste. This paper examines the factors that influence its potential for use as a partial replacement of Portland cement. Superplasticized mortars of equal workability containing ground crushed waste calcined-clay brick (GCWCCB) in the proportions of 10, 20, 30 and 40% as a cement replacement were analyzed through mechanical tests, pore structure characterization and durability tests. The results indicated the optimal percentages of substitution lies between 10% to 20%. The potential reduction of CO2 emissions could be as high as 10% of current Brazilian cement industry emissions if this approach were to be fully implemented, and it could be eligible for “Clean Development Mechanism” credits under Kyoto protocol. 相似文献
6.
Delba N.C. Melo Eduardo C. Vasco De Toledo Marcela M. Santos Salah D.M. Hasan Maria Regina Wolf Maciel Rubens Maciel Filho 《Computers & Chemical Engineering》2005,29(11-12):2485
In order to develop and test the integration procedure, in this paper a real time process integration involving the optimization and control of the process is presented, in this case, with the two-layer approach. The used optimization algorithms were Levenberg–Marquardt and SQP that solve a non-linear least square problem subject to bounds on the variables. The two-layer approach is a hierarchical control structure where an optimization layer calculates the set points and manipulated variables to the advanced controller, which is based on the dynamic matrix control with constraints (QDMC). The non-isothermal dynamic model of the three-phase slurry catalytic reactor with appropriate solution procedure was utilized in this work (Vasco de Toledo, E. C., Santana, P. L., Maciel, M. R. W., & Maciel Filho, R. (2001). Dynamic modeling of a three-phase catalytic slurry reactor. Chemical Engineering Science, 56, 6055–6061). The model consists on mass and heat balance equations for the catalyst particles as well as for the bulk phases of gas and liquid. The model was used to describe the dynamic behavior of hydrogenation reaction of o-cresol to obtain 2-methil-cyclohexanol, in the presence of a catalyst Ni/SiO2. 相似文献
7.
Hilde Lea Lein Kjell Wiik Mari-ann Einarsrud Tor Grande Edgar Lara-curzio 《Journal of the American Ceramic Society》2006,89(9):2895-2898
Steady-state compressive creep rate of La0.5 Sr0.5 Fe0.5 Co0.5 O3−δ (LSFC) and La0.5 Sr0.5 CoO3−δ (LSC) is reported in the temperature region 900°–1050°C and stress range 5–28 MPa. The stress exponents for the two materials were 1.71±0.18 and 1.24±0.15, respectively. The activation energy for creep was considerably higher for LSC (619±56 kJ/mol) than for LSFC (392±28 kJ/mol). The grain size exponent for LSC was 1.28±0.14. Considerably higher creep rates were observed for both materials in N2 compared with air. Relaxation by creep of chemical-induced stresses in oxygen-permeable membranes is addressed, especially at low partial pressure of oxygen. 相似文献
8.
Derek Lea 《计算机光盘软件与应用》2008,(2):94-97
智能对象的出现使得在Photoshop和Illustrator中使用像素和矢量之间的差别迅速消失。Derek Lea将会在制作一个结构完美且矢量明显的作品的同时为你解释原因。 相似文献
9.
10.
Andrielli Morais de Oliveira Flávio de Andrade Silva Eduardo de Moraes Rego Fairbairn Romildo Dias Toledo Filho 《Materials and Structures》2018,51(3):65
This paper reports the experimental findings on the tensile behavior of strain-hardening cement-based composites (SHCC). The composites were subjected to the combined effects of elevated temperatures and internal moisture condition. Uniaxial tensile tests on dumbbell-shaped SHCC specimens with in situ temperature control were performed at 22, 60 and 100 °C. In addition, the effect of the internal humidity of SHCC (95, 50, 20 and 0%) coupled to the elevated temperatures was investigated. It was shown that the tensile strength decreases and the strain capacity increases with an increase in temperature. The influence of the internal moisture conditions was more significant in high temperatures. The strain capacity reduced significantly with a decrease in the humidity level. The crack pattern of the SHCC specimens was determined. Furthermore, single fiber pullout tests were performed under the considered high temperatures condition. Finally, the results are discussed based on the thermogravimetry analysis of the PVA fiber, alterations on its microstructure and surface coating. 相似文献