全文获取类型
收费全文 | 86篇 |
免费 | 4篇 |
专业分类
化学工业 | 40篇 |
建筑科学 | 3篇 |
能源动力 | 1篇 |
轻工业 | 16篇 |
水利工程 | 2篇 |
无线电 | 1篇 |
一般工业技术 | 17篇 |
冶金工业 | 2篇 |
自动化技术 | 8篇 |
出版年
2023年 | 2篇 |
2022年 | 7篇 |
2021年 | 8篇 |
2020年 | 3篇 |
2019年 | 2篇 |
2018年 | 4篇 |
2017年 | 3篇 |
2016年 | 2篇 |
2015年 | 3篇 |
2014年 | 5篇 |
2013年 | 8篇 |
2012年 | 7篇 |
2011年 | 10篇 |
2010年 | 3篇 |
2009年 | 1篇 |
2008年 | 3篇 |
2007年 | 5篇 |
2006年 | 1篇 |
2005年 | 2篇 |
2004年 | 2篇 |
2003年 | 3篇 |
2002年 | 1篇 |
1998年 | 1篇 |
1997年 | 1篇 |
1991年 | 1篇 |
1972年 | 2篇 |
排序方式: 共有90条查询结果,搜索用时 0 毫秒
1.
Abstract Water use assessments are a necessary prerequisite for sustainable water resources management and planning in river basins, federal states, or countries. For reasons of transparency, flexibility, ease of update, and the possibility to generate scenarios of future water use, such assessments are best carried out by applying a water use model. To support water resources planning in two federal states of semi-arid Northeastern Brazil, Ceará and Piauí, the regional-scale water use model NoWUM was developed. It computes withdrawal and consumptive water use for each of 332 municipalities, distinguishing five water use sectors: irrigation, livestock, households, industry, and tourism. The model is suited to simulate the impact of global change and of management measures on water demand. Using NoWUM, the present-day water use situation in Ceará and Piauí is assessed. In addition, the impact of inter-annual climate variability and long-term climate change on irrigation requirements is considered. Scarce and uncertain input data lead to a high level of uncertainty in the model results. It is likely that water use in the most important sector, irrigation, is underestimated, while industrial water use is possibly overestimated. With some modifications, NoWUM has the potential to be applied for water use assessments in other data-poor regions of the globe. 相似文献
2.
Green tea seems to have a positive impact on health due to the therein-found flavanols. The amounts of these substances depend on tea preparation. In this paper, the influence of steeping time (3–7 min) and temperature (70–100 °C) on the content of the main flavanols in green tea (epicatechin EC, epicatechin gallate ECg, epigallocatechin EGC, and epigallocatechin gallate EGCg) is presented. Furthermore, additives (phosphate buffers, ascorbic acid in different amounts, and citric acid) are used to investigate the influence of pH, antioxidative, and chelating agents, simulating the addition of lemon juice or pure vitamin C. 相似文献
3.
Maike Gleichenhagen Benno F. Zimmermann Birgit Herzig Ingar Janzik Siegfried Jahnke Markus Boner Peter Stehle Rudolf Galensa 《Food chemistry》2013
The intrinsic isotopic labelling of plants with 13CO2 is an effective method to generate highly labelled compounds using photosynthesis and avoiding labour-intensive complex organic syntheses. In this study, the intrinsic isotopic labelling of polyphenols in parsley, spinach and peppermint is shown for the first time. The plants were grown in an atmosphere where 12CO2 was replaced by 13CO2, in order to generate highly labelled compounds. The total content of 13C as well as the individual polyphenols were analysed by Isotopic Ratio-MS and HPLC–Iontrap-MSn. 相似文献
4.
Petra Fallier-Becker Maike Nieser Ulrike Wenzel Rainer Ritz Susan Noell 《International journal of molecular sciences》2016,17(8)
The astrocytic endfoot membranes of the healthy blood-brain barrier—contacting the capillary—are covered with a large number of the water channel aquaporin 4 (AQP4). They form orthogonal arrays of particles (OAPs), which consist of AQP4 isoform M1 and M23. Under pathologic conditions, AQP4 is distributed over the whole cell and no or only small OAPs are found. From cell culture experiments, it is known that cells transfected only with AQP4-M1 do not form OAPs or only small ones. We hypothesized that in astrocytomas the situation may be comparable to the in vitro experiments expecting an upregulation of AQP4-M1. Quantitative Real-time PCR (qRT-PCR) of different graded astrocytomas revealed an upregulation of both isoforms AQP4 M1 and M23 in all astrocytomas investigated. In freeze fracture replicas of low-grade malignancy astrocytomas, more OAPs than in high-grade malignancy astrocytomas were found. In vitro, cultured glioma cells did not express AQP4, whereas healthy astrocytes revealed a slight upregulation of both isoforms and only a few OAPs in freeze fracture analysis. Taken together, we found a correlation between the decrease of OAPs and increasing grade of malignancy of astrocytomas but this was not consistent with an upregulation of AQP4-M1 in relation to AQP4 M23. 相似文献
5.
6.
Markus Böl Maike Sturmat Christine Weichert Cornelia Kober 《Computational Mechanics》2011,47(5):591-601
Active and passive experiments on skeletal muscles are in general arranged on isolated muscles or by consideration of the whole muscle packages, such as the arm or the leg. Both methods exhibit advantages and disadvantages. By applying experiments on isolated muscles
it turns out that no information about the surrounding tissues are considered what leads to insufficient specifications of
the isolated muscle. Especially, the muscle shape and the fibre directions of an embedded muscle are completely different
to that of the same isolated muscle. An explicit advantage, in contrast, is the possibility to study the mechanical characteristics
in an unique, isolated way. On the other hand, by applying experiments on muscle packages the aforementioned pros and cons
reverse. In such situation, the whole surrounding tissue is considered in the mechanical characteristics of the muscle which
are much more difficult to identify. However, an embedded muscle reflects a much more realistic situation as in isolated condition.
Thus, in the proposed work to our knowledge, we, for the first time, suggest a technique that allows to study characteristics
of single skeletal muscles inside a muscle package without any computation of the tissue around the muscle of interest. In
doing so, we use magnetic resonance imaging data of an upper arm during contraction. By applying a three-dimensional continuum
constitutive muscle model we are able to study the biceps brachii inside the upper arm and validate the modelling approach
by optical experiments. 相似文献
7.
Dario Van Meenen Annika Doege Emily Alefeld Andr Haase Manfred Beier Tobias Kiefer Eva Biewald Klaus Metz Oliver Drger Maike Anna Busch Nicole Dünker 《International journal of molecular sciences》2022,23(20)
A disintegrin and metalloproteinase (ADAM) family proteins, acting as sheddases, are important factors in a number of pathologies, including cancer, and have been suggested as promising therapeutic targets. The study presented focuses on the involvement of ADAM10 and ADAM17 in retinoblastoma (RB), the most common malignant intraocular childhood tumor. A significant correlation between ADAM17 expression levels and RB laterality and RB staging was observed. Levels of ADAM10 or ADAM17 regulating miRNAs miR-145, -152, and -365 were significantly downregulated in RB cell lines, and reduced miR levels with simultaneously upregulated ADAM10 and ADAM17 expression were found in RB patients. The involvement of both ADAMs analyzed in ectodomain shedding of the neuronal cell adhesion molecule L1 (L1CAM), shown to induce pro-tumorigenic effects in RB, was confirmed. Lentiviral ADAM10 and ADAM17 single or ADAM10/17 double knockdown (KD) induced caspase-dependent apoptosis and reduced cell viability, proliferation, growth, and colony formation capacity of RB cells. Moreover, differential phosphorylation of the serine/threonine kinase AKT was observed following ADAM17 KD in RB cells. Chicken chorioallantoic membrane (CAM) assays revealed that ADAM17 and ADAM10/17 depletion decreases the tumorigenic and migration potential of RB cells in vivo. Thus, ADAMs are potential novel targets for future therapeutic RB approaches. 相似文献
8.
Maike Timm‐Heinrich Xuebing Xu Nina Skall Nielsen Charlotte Jacobsen 《European Journal of Lipid Science and Technology》2003,105(8):436-448
Traditional sunflower oil (SO), randomized lipid (RL) and specific structured lipid (SL), both produced from SO and tricaprylin/caprylic acid, respectively, were stored for up to 12 wk to compare their oxidative stabilities by chemical and sensory analyses. Furthermore, the effect of adding a commercial antioxidant blend Grindox 117 (propyl gallate/ citric acid/ascorbyl palmitate) or gallic acid to the SL was investigated. The lipid type affected the oxidative stability: SL was less stable than SO and RL. The reduced stability was most likely caused by both the structure of the lipid and differences in production/ purification, which caused lower tocopherol content and higher initial levels of primary and secondary oxidation products in SL compared with RL and SO. Grindox 117 and gallic acid did not exert a distinct antioxidative effect in the SL oil samples during storage. 相似文献
9.
Since durum wheat is ∼20% more expensive than common wheat and considered of superior quality for the manufacture of pasta products, efficient methods for the detection of accidental or intentional admixtures of common wheat to durum wheat products are required. This paper describes a novel approach for the detection and quantification of whole grain common wheat adulteration in whole grain durum flour and dried pasta. We found that differences in the C17:0 to C21:0 alkylresorcinol homologue ratios between the two cereal species may serve as a suitable tool for whole grain durum product authentification. To detect and estimate adulteration, the C17:0/C21:0 ratios of flour and pasta admixtures with added whole grain flour of common wheat were analysed. A linear relationship between C17:0/C21:0 ratios and level of admixture in pasta samples showed that adulteration can be estimated within the range of 5–100% of admixture. Furthermore, di- and triunsaturated as well as oxygenated alk(en)ylresorcinols are reported to occur in Triticum durum Desf. for the first time. 相似文献
10.
Maike Timm‐Heinrich Xuebing Xu Nina Skall Nielsen Charlotte Jacobsen 《European Journal of Lipid Science and Technology》2003,105(8):459-470
Milk drinks containing 5% traditional sunflower oil (SO), randomized lipid (RL) or specific structured lipid (SL) (both produced from SO and tricaprylin/caprylic acid) were compared with respect to their particle size, viscosity and oxidative stability during storage. Furthermore, the effect of adding potential antioxidants EDTA or gallic acid to the milk drink based on SL was investigated. The lipid type significantly affected the oxidative stability of the milk drinks: Milk drink based on SL oxidized faster than milk drink based on RL or SO. The reduced oxidative stability in the SL milk drink could not be ascribed to a single factor, but was most likely influenced by the structure of the lipid and differences in the process applied to produce and purify the lipids. EDTA was a strong antioxidant, while gallic acid did not exert a distinct antioxidative effect in the milk drink based on SL. 相似文献