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1.
Karim Gharbi Louise Matthews James Bron Ron Roberts Alan Tinch Michael Stear 《Journal of the Royal Society Interface》2015,12(110)
Sea lice threaten the welfare of farmed Atlantic salmon and the sustainability of fish farming across the world. Chemical treatments are the major method of control but drug resistance means that alternatives are urgently needed. Selective breeding can be a cheap and effective alternative. Here, we combine experimental trials and diagnostics to provide a practical protocol for quantifying resistance to sea lice. We then combined quantitative genetics with epidemiological modelling to make the first prediction of the response to selection, quantified in terms of reduced need for chemical treatments. We infected over 1400 young fish with Lepeophtheirus salmonis, the most important species in the Northern Hemisphere. Mechanisms of resistance were expressed early in infection. Consequently, the number of lice per fish and the ranking of families were very similar at 7 and 17 days post infection, providing a stable window for assessing susceptibility to infection. The heritability of lice numbers within this time window was moderately high at 0.3, confirming that selective breeding is viable. We combined an epidemiological model of sea lice infection and control on a salmon farm with genetic variation in susceptibility among individuals. We simulated 10 generations of selective breeding and examined the frequency of treatments needed to control infection. Our model predicted that substantially fewer chemical treatments are needed to control lice outbreaks in selected populations and chemical treatment could be unnecessary after 10 generations of selection. Selective breeding for sea lice resistance should reduce the impact of sea lice on fish health and thus substantially improve the sustainability of Atlantic salmon production. 相似文献
2.
A therapist's theoretical orientation is likely to influence every facet of the therapeutic process. We explore the relationship of therapeutic orientation and self-monitoring style. To test the hypothesis that high self-monitors would be more eclectic than low self-monitors, we surveyed 30 intake therapists at a child guidance center. Results supported the hypothesis; those frequently using more than one orientation had higher self-monitoring scores. Furthermore, self-monitoring correlated negatively with psychoanalytic endorsement, but in a positive direction with behavioral, systems and eclectic endorsements. Results are discussed in terms of training needs of those differing in self-monitoring style. (PsycINFO Database Record (c) 2010 APA, all rights reserved) 相似文献
3.
The biological decolorization of two industrial, spent textile reactive dyebaths was investigated using a suspended-growth, halophilic mixed culture fed with glucose. Dyebath I contained mainly Reactive Blue 19 (RB19), an anthraquinone dye, whereas dyebath II contained mainly Reactive Blue 21 (RB21), a phthalocyanine dye. Batch assays under anaerobic conditions with the two neutralized dyebaths resulted in 87 and 37% extent of decolorization for dyebaths I and II, respectively. The rate of glucose utilization and the extent of acetate production were impacted in the presence of each dyebath as compared to the control culture. However, dyebath decolorization occurred despite moderate culture inhibition. Reuse of a biologically renovated RB19-containing dyebath in the dyeing process resulted in reproducible but not identical cotton fabric shades as compared to a standard dyeing (i.e., control) using fresh water. This difference is attributed to a variable degree of RB19 aggregation during the dyeing process and is not related to the efficiency of the biodecolorization process. Further improvement of the redyeing efficiency will lead to the development of an in-plant, closed-loop decolorization system resulting in significant water conservation and minimization of textile pollutants such as salt and dyes. 相似文献
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RM Bionta G Blewitt CB Bratton D Casper A Ciocio R Claus M Crouch ST Dye S Errede GW Foster W Gajewski KS Ganezer M Goldhaber TJ Haines TW Jones D Kielczewska WR Kropp JG Learned JM LoSecco J Matthews HS Park LR Price F Reines J Schulz S Seidel E Shumard D Sinclair HW Sobel JL Stone L Sulak R Svoboda G Thornton van der Velde JC C Wuest 《Canadian Metallurgical Quarterly》1987,36(1):30-36
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The effect of adsorption on the measurement of diffusion coefficients by the Taylor dispersion technique is investigated by modifying the governing equation to account for reversible, nonequilibrium adsorption. The resulting two-dimensional equations are solved by an explicit finite-difference technique. Experimental data for the acridine carbon dioxide system indicated that acridine adsorbs on the walls on the tubing and these data were investigated with this model. The influence of carious parameters including the number of sites and the rates of adsorption desorption was investigated by conducting a parametric sensitivity analysis on the model. It was found that adsorption of the solute on the wall of the tubing could produce an error as high as 35% on the measured diffusion coefficient compared to the actual diffusion coellicient. Examination of the influence of each of the parameters will enable Inure investigators to reduce the effect of adsorption in the measurement of diffusion coefficients by Taylor dispersion. 相似文献
8.
Several areas of current interest in the neuropsychology of epilepsy are briefly reviewed in this article. These include variables pertaining to seizures, seizure history, antiepileptic drugs, and methods of neuropsychological evaluation. It is apparent that epilepsy is a multifaceted area: Psychologists not only can be of great assistance to patients with this condition, but may also learn a great deal from this complex disorder. (PsycINFO Database Record (c) 2010 APA, all rights reserved) 相似文献
9.
Scientists sometimes spend hours conducting experiments only to find that the resulting data proves difficult to analyze with traditional visualization techniques. A typical laboratory experiment, for example, will setup several systems in each of two or more groups-a control group and various treatment groups. The investigator will then measure various parameters for each system over time (sometimes dozens to hundreds of parameters). The investigator tries to answer this question: What is different between the control and treatment groups? Field monitoring of polluted and unpolluted sites within a region result in the same kinds of data and the same difficulties in visualization. Plotting multiple lines on a single 2D plot quickly gets confusing. Plus, the dynamic interactions between parameters can be hard to see. 3D visualizations help researchers make qualitative insights about data more easily. We developed a 3D plotting technique, called “worm plots”, for visualizing these kinds of data. Our visualization tool examines how groups of points change over time. If we plot circles for each time slice, then these circles will change their relative sizes and positions as time goes by. To visualize these evolving dynamics, we connect these time slices with conic sections. This gives us spacetime worms that can be displayed graphically. In our experience, these simple circular cross sections work best when exploring data. They can be rendered quickly and give an easily intuited summary of each group. Further enhancements tend to make the image busy and difficult to interpret 相似文献
10.
Emery Robert E.; Matthews Sheila G.; Kitzmann Katherine M. 《Canadian Metallurgical Quarterly》1994,62(1):124
A 1-yr follow-up study was conducted on families randomly assigned to settle custody disputes either in mediation or through adversary procedures. Consistent with Time 1 reports, at Time 2 fathers who mediated were substantially more satisfied than were fathers who litigated. Fathers who mediated also complied more with child support orders. Contrary to prediction, the greater satisfaction and compliance of fathers did not lead to increased satisfaction among mothers who mediated. In contrast to Time 1, at follow-up mothers who mediated were significantly less satisfied than were mothers who litigated, but selective attrition may account for these differences. The psychological adjustment of mothers and fathers was not significantly different between settlement groups at Time 2, but mothers in both groups reported less satisfaction with dispute settlement and less dysphoria at Time 2 than they had reported at Time 1. (PsycINFO Database Record (c) 2010 APA, all rights reserved) 相似文献