基于容错度自适应支持向量机的液压泵故障诊断

针对已有在线故障诊断方法在数据量大、噪声强条件下分类速度较低、分类精度不够高等问题,结合液压泵故障类别数目大、工作环境恶劣的特点,提出了一种适用于混凝土泵车液压泵在线诊断的状态识别算法——容错度自适应支持向量机。该方法主要从四个方面对分类速度做了改进：①引入容错度因子进行模型训练;②优先选择能将某一类故障样本单独分离出来的二分类器;③在满足②的基础上选择平均支持向量机少的分类器;④引入增量学习算法对参数进行自适应调整,提高多故障诊断中对新故障类别和新故障数据的适应性,保证系统的分类精度。通过对混凝土泵车的液压泵故障诊断,证明了该方法在明显提高分类速度的同时保证了较高的分类精度。     

A theory of rectangular dual graphs

Arectangular graph is a plane graph where all regions are four-sided and all edges are oriented in either the vertical or the horizontal direction. In addition the graph enclosure must also be rectangular. Given a plane graph representing a desired component connectivity, itsrectangular dual can be used to build afloorplan. This indicates that a system implementation can allocate rectangular floorplan regions to components that can be pairwise connected through common borders. This paper proves that constructing a rectangular dual graph is equivalent to a matching problem in a bipartite graph derived from the given plane graph. A simple existence theorem in terms of the graph structure is obtained as a corollary.     

A theory of rectangular dual graphs

Arectangular graph is a plane graph where all regions are four-sided and all edges are oriented in either the vertical or the horizontal direction. In addition the graph enclosure must also be rectangular. Given a plane graph representing a desired component connectivity, itsrectangular dual can be used to build afloorplan. This indicates that a system implementation can allocate rectangular floorplan regions to components that can be pairwise connected through common borders.This paper proves that constructing a rectangular dual graph is equivalent to a matching problem in a bipartite graph derived from the given plane graph. A simple existence theorem in terms of the graph structure is obtained as a corollary.This work was supported by the National Science Council, Taiwan, Republic of China, under Contract NSC 78-0404-E006-14.     

The AIMS2-SF: a short form of the Arthritis Impact Measurement Scales 2. French Quality of Life in Rheumatology Group

OBJECTIVE: To develop a short form of the Arthritis Impact Measurement Scales 2 (AIMS2) questionnaire, preserving content validity as the priority criterion. METHODS: A 2-step reduction procedure was used: 1) Delphi technique, with 1 panel of patients and 1 panel of experts each selecting 1 set of items independently; and 2) nominal group technique, where members of both panels reached consensus on the final selection of items, using information derived from item analysis. Psychometric properties of the AIMS2-Short Form (AIMS2-SF) and AIMS2 were compared using data from a cohort of 127 rheumatoid arthritis patients who completed the AIMS2 twice prior to the initiation of methotrexate (MTX) treatment and 3 months post-initiation of MTX treatment. RESULTS: The 2 panels reached consensus on a 26-item AIMS2-SF (54.4% reduction from the AIMS2). Factor analysis showed preservation of the 5-component structure. Convergent validity (Physical and Symptom components with clinical variables: r = 0.24-0.59), test-retest reproducibility (intraclass correlation coefficient >0.7), and sensitivity to change at 3 months (standardized response mean 0.36-0.8, except Social Interaction component [0.08]) were very close to the values for the original AIMS2. CONCLUSION: The AIMS2-SF is a shorter version of the AIMS2 (i.e., available in 2-page format) and has psychometric properties similar to those of the AIMS2.     

综采工作面运输巷超前支护设备的设计

介绍了新型综采工作面运输巷超前支护设备的结构和工作过程,以及超前支护支架组与转载机、破碎机等设备的配套关系。该型超前支护设备的成功研制为综采工作面运输巷超前支护实现机械化提供了新的尝试。     

FinFET based ultra-low power 3T GC-eDRAM with very high retention time in sub-22 nm

Analog Integrated Circuits and Signal Processing - This paper presents an ultra-low power 3T gain-cell embedded DRAM (GC-eDRAM) cell in fin field-effect transistor (FinFET). This memory structure...     

浅析如何解决液压支架立柱油缸装配过程中的导向套烧丝问题

作为液压支架的重要组成部分,立柱油缸为有效地支撑和控制工作面顶板提供主驱动力。因而,立柱油缸的产品质量将对液压支架的使用寿命产生决定性影响。通过引入现场实证分析．本文对立柱油缸装配过程中导向套烧丝的原因展开细致分析,并提供了有效的预防对策以及处理建议。     

Interleukin-4 and interleukin-10 are chondroprotective and decrease mononuclear cell recruitment in human rheumatoid synovium in vivo

We used the severe combined immunodeficient (SCID) mouse model to assess the effect of interleukin-4 (IL-4) or IL-10 injection on cartilage degradation and mononuclear cell (MNC) recruitment to human rheumatoid synovium in vivo. Human rheumatoid synovium and cartilage from five rheumatoid arthritis patients, obtained after joint replacement surgery, were engrafted subcutaneously to 6-8-week-old SCID CB17 mice. Synovial tissues were injected with recombinant human IL-4 (rhIL-4, 100 ng; rhIL-10, 100 ng), both cytokines, or tumour necrosis factor-alpha (TNF-alpha) (1000 U), or phosphate-buffered saline twice a week for 4 weeks. The graft was removed and immunochemical analysis was carried out to assess intracellular adhesion molecule-1 (ICAM-1), vascular cell adhesion molecule-1 (VCAM-1) and E-selectin expression. Moreover, cartilage degradation was assessed through the quantification of the erosion surface on a computerized image of the engrafted cartilage at high power view. MNC recruitment in the synovial tissue was determined by labelling blood MNC with indium-111 before their intraperitoneal injection. The activity obtained in the region of the graft were determined with a gamma camera 72 hr postinjection. The results are expressed as a percentage of initial injected activity. After 4 weeks we observed a decrease of cartilage area in controls (77 +/- 8%), inhibited after injection of IL-4, IL-10, or both cytokines (90 +/- 3%, 89.1 +/- 4%, 89.2 +/- 5% respectively), and 57 +/- 17% after TNF-alpha injection. The % MNC activity in the graft decreased to 77 +/- 81% (NS), 9 +/- 4% (P < 0.003) and 19 +/- 6% (P < 0.007) compared with untreated synovial tissue after treatment with IL-4, IL-10, or both cytokines, respectively. Moreover, IL-10 but not IL-4 decreased the expression of ICAM-1 but not VCAM-1 or E-selectin by synovial cells. These results suggest that IL-10 and IL-4 could have chondroprotective properties, and that IL-10 but not IL-4 inhibits MNC traffic towards the synovial tissue efficiently.     

Adenovirus-mediated transfer of viral IL-10 gene inhibits murine collagen-induced arthritis

IL-10 is a potent anti-inflammatory cytokine that has received growing attention for its therapeutic potential. We examined the efficiency of adenoviral-mediated gene transfer of IL-10 on the incidence and severity of murine collagen-induced arthritis (CIA). Male DBA1 mice immunized with collagen II were treated by systemic administration of 10(9) plaque-forming units of replication-defective adenoviral vector expressing viral IL-10 (vIL-10) on day 30, when clinical symptoms of arthritis start. The transgene was shown to inhibit the onset of CIA, to decrease severity, and profoundly suppress the overall joint histopathology of the experimental arthritis. Significant IL-10 concentrations were obtained in the serum of injected animals for 7 days. Inhibition of arthritis was enhanced by administration of increasing doses of adenovirus-vIL-10. In addition, the local immunosuppressive effect of gene-delivered vIL-10 could be neutralized by a monoclonal anti-vIL-10 Ab. The CIA symptoms in the group treated with the same construct expressing inactive vIL-10 (vIL-10 mut) were similar to those in untreated animals. Our data indicate that a single systemic administration of an adenoviral vector encoding vIL-10 may be a good candidate to suppress arthritis.