Education, occupation and health status of people of age five years or more living in a high density urban area in Zimbabwe

OBJECTIVE: To find out the education, occupation and health status of people aged five years or more living in a high density urban area in Zimbabwe. DESIGN: Cross sectional. SETTING: Households in Chitungwiza. SUBJECTS: Persons of age five years or more available in a household at the time of the survey. In 1990 and 1993, 822 and 1,023 people were surveyed, respectively. MAIN OUTCOME MEASURES: Educational level, employment, rate of smoking, nutritional status, blood pressure level, and rate of disability. RESULTS: After the age of 24 years, more males than females were observed in both periods. A much higher proportion (x2 = 20.34, df = 1, p < 0.001) of women were in informal employment in 1993 (28.6%) than in 1990 (12.9%). Meanwhile, about an equal proportion of men were in the informal sector in both periods (12.0% and 10.4% in 1990 and 1993, respectively). For females of age 15 years or more, fewer (40.8%) had attained secondary education than males (76.4%) in 1990 (x2 = 50.2, df = 1, p < 0.001). Overall, 208 (36.1%) men and eight (1.3%) women of age 15 years or more smoked. Raised blood pressure for both sexes increased significantly with age (x2 for linear trend = 20.21 for men and 65.81 for women, df = 1, p < 0.001 for both sexes). More women of age 45 years or more had raised blood pressure than men (x2 = 4.67, df = 1, p = 0.031). Many more women (8.0%) than men (0.7%) had a Ponderal Index of greater than 27 (x2 = 19.33, df = 1, p < 0.001). A total of 12 (1.5%) persons were disabled. CONCLUSION: Raised blood pressure and obesity mainly affected women and interventions to improve their health is recommended.     

Malaria in Zimbabwe: comparisons of IFAT levels, parasite and spleen rates among high, medium and lower altitude areas and between dry and rainy seasons

OBJECTIVES: To study the extent of malaria prevalence among children at various elevations above sea level and in children during the dry and rainy seasons in Zimbabwe. DESIGN: Cross sectional. SETTING: Primary and secondary schools. SUBJECTS: The number of children (aged about eight years in Grade Three and 13 years in Form One) examined in November 1992 was 103 in Chitungwiza (above 1,200 m), 94 in Gokwe (900 to 1,200 m) and 96 in Sasame (under 900 m). In April 1993 it was 86 in Chitungwiza, 78 in Gokwe and 81 in Sasame. MAIN OUTCOME MEASURE: Indirect Fluorescent Antibody Test (IFAT) levels, parasite and spleen rates. RESULTS: No splenomegaly was detected in children in schools above 900 m. While no parasitaemia was detected in children in schools above 1200 m, one (0.6%, 95% CI to -0.6 to 1.7) child and 37 (20.9%, 95% CI 14.9 to 26.9) children in schools between 900 and 1,200 m and below 900 m, respectively, had parasitaemia. The IFAT levels were lowest in children in areas above 1,200 m and increased significantly with decreasing altitude (x2 for linear trend 332, p < 0.001). The parasite rate in the rainy season (39.5%, 95% CI 28.9 to 50.2) was significantly (p < 0.001) higher than that in the dry season (5.2%, 95% CI 0.8 to 9.7). No significant differences in the IFAT levels (p = 0.208) and in the spleen rates (p = 0.180) were observed between the dry and rainy seasons. Sixty five percent of all children in schools above 1,200 m visiting rural areas used no protective measures against malaria. All children in schools under 900 m reported that their homes were sprayed, but very few other prophylactic measures (seven children used antimalarial drugs and 15 children used a net) were reported. CONCLUSIONS: Malaria acquisition is uncommon above 900 m and the people in these areas are highly vulnerable to malaria.     

Effect of interion interactions on electrolyte properties near a phase separation boundary

The interaction of ions in solution and in the adsorbed state with themselves and with charges induced in the solid phase varies the isotherms of ion adsorption and the structure of the diffusion part of a double electric layer. This effect is treated within the Debye-Huckel approximation for a dilute solution of a strong electrolyte under conditions of local thermodynamic equilibrium.Translated from Inzhenerno-fizicheskii Zhurnal, Vol. 61, No. 4, pp. 586–597, October, 1991.     

Biosynthesis of glyceride glycoside (nonionic surfactant) by amylosucrase,a powerful glycosyltransferase

Amylosucrase (ASase, E.C. 2.4.1.4) is a powerful transglycosylation enzyme that can transfer glucose from sucrose to the hydroxyl (-OH) group of various compounds. In this study, recombinant ASases from Deinococcus geothermalis (DgAS) and Bifidobacterium thermophilum (BtAS) were used to synthesize biosurfactants based on the computational analysis of predicted docking simulations. Successful predictions of the binding affinities, conformations, and three-dimensional structures of three surfactants were computed from receptor-ligand binding modes. DgAS and BtAS were effective in the synthesis of biosurfactants from glyceryl caprylate, glyceryl caprate, and polyglyceryl-2 caprate. The results of the transglycosylation reaction were consistent for both ASases, with glyceryl caprylate acceptor showing the highest concentration, as confirmed by thin layer chromatography. Furthermore, the transglycosylation reactions of DgAS were more effective than those of BtAS. Among the three substrates, glyceryl caprylate glycoside and glyceryl caprate glycoside were successfully purified by liquid chromatography–mass spectrometry (LC–MS) with the corresponding molecular weights.     

The distribution of Schistosoma haematobium in the Isoka district, Zambia; and a possible strategy for its control

The distribution of schools prevalent for Schistosoma haematobium in the Isoka district, Zambia was estimated by examining haematuria in the urine of the pupils found in Grades Three, Four or Five using reagent sticks. Thirty three (57 pc) schools had prevalence rates of 25 pc or more. The distribution of S. haematobium was patchy with significant differences in prevalence rates between some areas only short distances apart. A sociological study in the same schools showed that 68 (97 pc) head/senior teachers associated the disease with blood in urine and agreed to perform a reagent stick test on their pupils' urine. Thirty five (50 pc) of these respondents considered S. haematobium infection as a major problem and 66 (94 pc) of them were ready to administer a diagnostic questionnaire to their pupils in a study to identify high risk schools for S. haematobium. We conclude that the identification of high risk schools in the Isoka district, Zambia, using a diagnostic questionnaire and reagent stick testing by teachers, should proceed as a step to controlling S. haematobium infection in the district.     

Whole-cell bioconversion using non-Leloir transglycosylation reactions: a review

Food Science and Biotechnology - Microbial biocatalysts are evolving technological tools for glycosylation research in food, feed and pharmaceuticals. Advances in bioengineered Leloir and...