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The ActA protein is an essential determinant of pathogenicity that is responsible for the actin-based motility of Listeria monocytogenes in mammalian cells and cell-free extracts. ActA appears to control at least four functions that collectively lead to actin-based motility: (1) initiation of actin polymerization, (2) polarization of ActA function, (3) transformation of actin polymerization into a motile force and (4) acceleration of movement mediated by the host protein profilin.  相似文献   
3.
We present a study of magneto-thermal instabilities in polycrystalline MgB2 superconductor, by magnetic hysteresis loop measurements and by investigations of magnetic flux dynamics with a miniature Hall probe. Temperature and magnetic field ranges where the flux jumps may be observed have been determined. On the basis of measurements of the magnetic flux dynamics, an average magnetic diffusivity describing the process of the flux jump is estimated. This parameter is compared with the thermal and magnetic diffusivities calculated on the basis of available data for thermal conductivity, heat capacity and resistivity. It is shown that the estimated value of the field of the first flux jump is influenced significantly by the field dependence of specific heat. In order to explain the observed phenomenon, the temperature reached by the sample during the flux jump at different magnetic fields is calculated.  相似文献   
4.
1 俄联邦防爆电气设备应用情况 传统上快速发展的工业部门如进行石油和天然气生产、运输以及加工处理的那些部门、石油化工行业,以及很多可能出现爆炸性环境的其他行业,在其一些场所中需要使用防爆电气设备。  相似文献   
5.
Actin filament assembly at the cell surface of the pathogenic bacterium Listeria monocytogenes requires the bacterial ActA surface protein and the host cell Arp2/3 complex. Purified Arp2/3 complex accelerated the nucleation of actin polymerization in vitro, but pure ActA had no effect. However, when combined, the Arp2/3 complex and ActA synergistically stimulated the nucleation of actin filaments. This mechanism of activating the host Arp2/3 complex at the L. monocytogenes surface may be similar to the strategy used by cells to control Arp2/3 complex activity and hence the spatial and temporal distribution of actin polymerization.  相似文献   
6.
An experiment was performed to test a distinct-window conferencing screen design as an electronic cue of social status differences in computer-mediated group decision-making. The screen design included one distinct window to symbolize high-status, and two nondistinct windows to symbolize low-status. The results indicated that the distinct-window screen design did produce status affects in groups of peers making decisions on judgmental problems. Randomly assigned occupants of the distinct window had greater influence on group decisions and member's attitudes than occupants of nondistinct windows.The authors would like to thank Shyam Kamadolli and Phaderm Nangsue, the programmers who developed the software used in this experiment. We would also like to thank the editor and our three anonymous reviewers for exceedingly helpful comments on an earlier draft of this article.  相似文献   
7.
Ti3C2 MXenes with different halogen modifications are prepared rapidly and efficiently by microwave molten salt method, and the MXene surface functional group modification is successfully achieved to address the problems of low purity, complex functional groups, and uncontrollable energy band structure of MXenes obtained by traditional liquid phase etching. Among them, the modification of the iodine (I) functional group onto the surface of Ti3C2 changes the energy band structure and band gap, resulting in easier photoexcitation and more photogenerated carriers. The increased Fermi energy is closer to the conduction band, the decreased surface work function weakens the electron confinement ability. The photogenerated carriers can migrate to the surface of the material more easily with extended lifetime, so the activity of the catalyst is improved. Further, for gaseous monomeric mercury (Hg0) photo-oxidative removal, Ti3C2-I2 exhibits 85.5% efficiency of Hg0 photo-oxidative removal under visible light. Based on the experimental characterization and density functional theory calculations, a mechanism for the photo-oxidative removal of Hg° from Ti3C2-I2 MXene is proposed, which provides a valuable strategy for studying Ti3C2 MXenes in the field of photocatalysis.  相似文献   
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Using virtual reality (VR) to examine risky behavior that is mediated by interpersonal contact, such as agreeing to have sex, drink, or smoke with someone, offers particular promise and challenges. Social contextual stimuli that might trigger impulsive responses can be carefully controlled in virtual environments (VE), and yet manipulations of risk might be implausible to participants if they do not feel sufficiently immersed in the environment. The current study examined whether individuals can display adequate evidence of presence in a VE that involved potential interpersonally-induced risk: meeting a potential dating partner. Results offered some evidence for the potential of VR for the study of such interpersonal risk situations. Participants’ reaction to the scenario and risk-associated responses to the situation suggested that the embodied nature of virtual reality override the reality of the risk’s impossibility, allowing participants to experience adequate situational embedding, or presence.  相似文献   
10.
The paper considers local bending effects induced in the vicinity of inserts in sandwich panels. Such local bending effects are associated with an increase of bending stresses in the sandwich faces and normal and shear stresses in the sandwich core. An earlier developed analytic model [Proceedings of the Sixth International Conference on Sandwich Structures (ICSS-6) (2002) 551] is adapted for the case of a sandwich panel with circular insert, with elastic properties differing from those of the core. The locally induced stresses in the faces and core due to presence of the insert are expressed via simple analytic relations (and charts) enabling an estimation of these local stresses. Finite element analysis is employed to demonstrate the applicability of the analytic model, and a good correspondence between the numerical and the analytical data is found. A study case related to marine applications, namely a circular insert in a sandwich deck panel used for mounting of a rigging fixture, is considered, and optimization of an existing design is carried out.  相似文献   
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