管道企业的计划管理与成本控制

近几年 ,我国管道企业通过加强资金预算控制 ,实行资金集中管理 ,推行目标成本管理等措施 ,使企业成本得到了有效的控制 ,取得了较好的效果。本文仅从计划管理方面探讨管道企业成本控制的潜力     

A new class of dynamic macrosystem models with self-reproduction

"The author considers a class of macrosystems where the relaxation time of the distribution process of elements is significantly less than the relaxation time of the self-reproduction process. The proposed model of such macrosystems defines the system of differential equations with nonlinearity generated by the solution of a mathematical programming problem with an entropy objective function. Methods for the structural analysis of this model are considered, and applications to demographic modelling, biological dynamics and chemical kinetics are given."     

Ultra-low noise single-photon detector based on Si avalanche photodiode

We report operation and characterization of a lab-assembled single-photon detector based on commercial silicon avalanche photodiodes (PerkinElmer C30902SH, C30921SH). Dark count rate as low as 5 Hz was achieved by cooling the photodiodes down to -80 °C. While afterpulsing increased as the photodiode temperature was decreased, total afterpulse probability did not become significant due to detector's relatively long deadtime in a passively-quenched scheme. We measured photon detection efficiency >50% at 806 nm.     

Presence, molecular characteristics and geosmin producing ability of actinomycetes isolated from South Korean terrestrial and aquatic environments

The unpleasant odor of drinking water is one of the major problems in many water utilities in the world. Actinomycetes have long been associated with odorous compounds. Considering the paucity of research on Actinomycetes producing odorous compounds in South Korea, presence of Actinomycetes, their molecular characteristics and ability to produce odorous compounds were investigated in this study. Findings confirmed the presence of Actinomycetes in surface soil, sediment, and water samples from four sites: two artificial lakes [Paldang and Cheongpyeong (CP)], and two streams [Gyeongan (GA) and Yangpyeong]. Surface soil and sediment from CP area had the greatest concentration of Actinomycetes (8.2 x 10(7) and 6.8 x 10(6) colony forming units (CFUs)/gram, dry weight, respectively). When water samples are considered, samples from GA had the highest concentration (1.9 x 10(2) CFU/mL). 16S rRNA sequencing and molecular phylogenetic analysis showed that Streptomyces was the dominant genus (64.1%). In addition, the isolated Actinomycetes synthesized 5.4 ng/L geosmin as demonstrated by thermal desorption unit-gas chromatograph/mass spectrometry analysis.     

Conical microlens arrays that flatten optical-irradiance profiles of nonuniform sources

One can create conical microlens arrays on a glass plate by simply spin coating spin-on-glass film on the glass, patterning the photoresist, and then etching the glass in a HF solution. These arrays can be used to obtain more-uniform irradiance profiles from nonuniform incoherent sources.     

Distance- and velocity-detection interferometer by using a frequency triangular-modulated laser diode

A scheme for distance and velocity signal detection is implemented. This technique is based on a laser diode with its frequency modulated by a triangular waveform and followed by time gating.     

Estimation of optical constants of thin film by the use of artificial neural networks

A system for analyzing single-layer optical thin films has been formulated by the use of artificial neural networks. The training data sets stem from the computational results of the physical model of thin films, and they are used to train the artificial neural network, which, when done, can give values of film parameters in the millisecond time regime. The fast backpropagation algorithm is employed during training. The results of training are also given.     

Design and fabrication of a diffractive phase element for wavelength demultiplexing and spatial focusing simultaneously

The design of a diffractive phase element (DPE) that simultaneously implements wavelength demultiplexing and focusing is carried out on the basis of the general theory of amplitude-phase retrieval. The designed DPE is fabricated with optical contact lithography. Three masks are needed to produce the surface-relief structure of the DPE with eight quantized levels in depths. Experiments demonstrate that the designed DPE can successfully implement both the functions of demultiplexing three different-wavelength beams and focusing each component at a predesignated position simultaneously. Experimental measurements are in good agreement with the results of numerical simulations.     

微软春秋

2008年,微软到了转折的重大关口。建立在PC时代的微软帝国,在互联网时代来临之时像一个日渐没落的帝国,流露出既措手不及又茫然无助的神情。我们回顾微软历史时不难发现,微软今日的命运几乎早已注定,因为它的商业模式早已落伍。     

Overexpression and elevated plasma level of tumor-associated antigen 90K/Mac-2 binding protein in colorectal carcinoma

The cancer cell secretome may contain potentially useful biomarkers. Previously, we have analyzed the colorectal carcinoma (CRC) cell secretome. In this study, tumor‐associated antigen 90K (TAA90K)/Mac‐2 binding protein (Mac‐2BP), one of the CRC cell secreted proteins, was chosen for evaluation as a potential CRC biomarker because its mRNA level was also found to be significantly elevated in CRC tissues and in a more metastatic CRC cell line from the analysis of two public domain array‐based datasets. Immunohistochemical analysis of 241 CRC specimens showed that TAA90K/Mac‐2BP was positively detected in 52.7% of the tumors, but weakly or not detected in over 95% of the adjacent nontumor epithelial cells. The plasma TAA90K/Mac‐2BP levels were significantly higher in CRC patients (N = 280) versus healthy controls (N = 147) (7.77 ± 3.49 vs. 5.72 ± 2.67 μg/mL, p<0.001). Moreover, combination of TAA90K/Mac‐2BP and carcinoembryonic antigen (CEA) could outperform CEA alone in discriminating CRC patients from healthy persons in this case‐control study. Our results collectively indicate that analysis of cancer cell secretome is a feasible strategy for identifying cancer biomarker candidates, and the TAA90K/Mac‐2BP may be a potential CRC biomarker.