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1.
The problem of error estimation in the numerical solution of integral equations that arise in electromagnetics is addressed. The direct method (Green's theorem or field approach) and the indirect method (layer ansatz or source approach) lead to well-known integral equations both of the first kind [electric field integral equations (EFIE)] and the second kind [magnetic field integral equations (MFIE)]. These equations are analyzed systematically in terms of the mapping properties of the integral operators. It is shown how the assumption that field quantities have finite energy leads naturally to describing the mapping properties in appropriate Sobolev spaces. These function spaces are demystified through simple examples which also are used to demonstrate the importance of knowing in which space the given data lives and in which space the solution should be sought. It is further shown how the method of moments (or Galerkin method) is formulated in these function spaces and how residual error can be used to estimate actual error in these spaces. The condition number of all of the impedance matrices that result from discretizing the integral equations, including first kind equations, is shown to be bounded when the elements are computed appropriately. Finally, the consequences of carrying out all computations in the space of square integrable functions, a particularly friendly Sobolev space, are explained 相似文献
2.
Shen-Fu Hsiao Jia-Siang Yeh 《Electronics letters》1998,34(12):1180-1182
A pass-transistor based cell library containing only two types of cells is designed and a corresponding logic/circuit synthesiser developed for logic mapping of any combinational circuit. The proposed design has better performance than the recently proposed lean integration with pass transistors (LEAP) cell library. Furthermore, the modified LEAP cell library can be easily migrated to a new process technology due to the smaller number of cells 相似文献
3.
CM Tsai SH Hsiao CM Frey KT Chang RP Perng AF Gazdar BS Kramer 《Canadian Metallurgical Quarterly》1993,53(5):1079-1084
Both cisplatin (CDDP) and leucovorin (LV) have been shown to enhance cytotoxicity of 5-fluorouracil (FUra) against murine and human neoplasms by increasing intracellular reduced folate concentrations. We were interested in their use in a combination to inhibit non-small cell lung cancer (NSCLC) cell growth and therefore conducted an in vitro study to investigate the cytotoxic activities of combinations of CDDP plus FUra, with and without LV (20 microM), against seven NSCLC cell lines. A tetrazolium assay with application of the classical isobole method was used to test drug combinations. We found that LV enhanced FUra but not CDDP cytotoxicity and that the degree of enhancement was negatively correlated with the effect of FUra. There was an overall additive combination effect of CDDP plus FUra, although there may be synergy at higher effect levels. There was synergy to a combination of CDDP, FUra, and LV, presumably primarily related to the synergistic effects of adding LV to FUra. In summary, LV and CDDP enhanced FUra cytotoxicity in a complementary fashion and there was clear synergy of a combination of CDDP, FUra, and LV against a panel of NSCLC cell lines. Our in vitro results provide a rationale for controlled clinical studies of this three-drug regimen in patients with NSCLC. 相似文献
4.
Forty-three patients with spastic quadriplegia (mean age 7.9 years, range 3.3 to 17.2 years) underwent bone mineral density (BMD) measurement of the lumbar spine and were evaluated between 2.6 and 5.5 years (mean 3.8) later to determine whether this measurement had predicted risk of fracture over the subsequent period of observation. Other potential risk factors that were evaluated include body weight z score, serum vitamin D levels, previous fracture, and hip spica casting. The baseline measurements showed that BMD falls further below normal with increasing age and was more than one standard deviation below age-matched normal mean in 38 of the 43 patients. Fracture rate did not differ between those with low and those with very low spinal BMD. Similarly, serum vitamin D levels and body weight z scores were not predictive of fracture. However, fracture rate was over fourfold greater following spica casting and more than threefold greater following an initial fracture. Fracture rates in the study group were similar to those reported for age- and sex-matched normal children, though generally the location of the fractures and mechanisms of injury differed. 相似文献
5.
In this paper, an analytic current-voltage model for submicrometer fully-depleted (FD) silicon-on-insulator (SOI) MOSFET's is presented. This model takes into account the source/drain series resistances which can be especially high in thin film SOI devices. The effect of drain induced conductivity enhancement is also included, which is important for submicrometer channels. The model is verified by comparison to measured SOI I-V characteristics. Good agreement is obtained for SOI film thicknesses ranging from 40 to 220 nm and effective channel lengths down to 0.25 μm 相似文献
6.
An algorithmic approach was used to select recoveries for non-sharp sequence designs. Simple distillation columns were employed. The non-key component distribution was modeled using the Fenske equation. The combination of producing impure products and allowing non-key component distribution, results in a large search space. With this large search space size and software limitations, five problems were solved (see summary table in the Design Examples sub-section). The optimal non-key component distribution was found to be significant but not necessarily maximal. Parallel processing was selected as optimal in contrast to the more traditional sequential processing. 相似文献
7.
The singular value decomposition (SVD) of complex matrices is computed in a highly parallel fashion on a square array of processors using Kogbetliantz's analog of Jacobi's eigenvalue decomposition method. To gain further speed, new algorithms for the basic SVD operations are proposed and their implementation as specialized processors is presented. The algorithms are 3-D and 4-D extensions of the CORDIC algorithm for plane rotations. When these extensions are used in concert with an additive decomposition of 2×2 complex matrices, which enhances parallelism, and with low resolution rotations early on in the SVD process, which reduce operation count, a fivefold speedup can be achieved over the fastest alternative approach 相似文献
8.
This paper reports the result of studies using a biotrickling filter with blast-furnace slag packings (sizes = 2–4 cm and specific surface area = 120 m2∕m3) for treatment of styrene in an airstream. The effects of volumetric styrene loading L, superficial gas velocity U0 and liquid recirculation rate VL on the styrene elimination capacity K, and the removal efficiency K∕L were tested. Variations of styrene concentration with packing height as well as rates of nutrient utilization were also tested. The results show that for L< 30 g∕m3?h, K∕L was nearly independent of U0 in the range of 29–67 m∕h and was independent of VL in the range of 3.84–9.60 m∕h. In this range, the rate of styrene removal was both reaction and diffusion limited and the reaction was of zero-order kinetics. For higher loadings, K∕L decreased with increasing U0 and increased with increasing VL and the system approached the condition of reaction limitation. 相似文献
9.
Ming-Yen Hsiao Ya-Wen Wu Wen-Shiang Chen Yu-Ling Lin Po-Ling Kuo Chueh-Hung Wu 《International journal of molecular sciences》2021,22(7)
Entrapment neuropathy (EN) is a prevalent and debilitative condition caused by a complex pathogenesis that involves a chronic compression–edema–ischemia cascade and perineural adhesion that results in excessive shear stress during motion. Despite decades of research, an easily accessible and surgery-free animal model mimicking the mixed etiology is currently lacking, thus limiting our understanding of the disease and the development of effective therapies. In this proof-of-concept study, we used ultrasound-guided perineural injection of a methoxy poly(ethylene glycol)-b-Poly(lactide-co-glycoilide) carboxylic acid (mPEG-PLGA-BOX) hydrogel near the rat’s sciatic nerve to induce EN, as confirmed sonographically, electrophysiologically, and histologically. The nerve that was injected with hydrogel appeared unevenly contoured and swollen proximally with slowed nerve conduction velocities across the injected segments, thus showing the compressive features of EN. Histology showed perineural cellular infiltration, deposition of irregular collagen fibers, and a possible early demyelination process, thus indicating the existence of adhesions. The novel method provides a surgery-free and cost-effective way to establish a small-animal model of EN that has mixed compression and adhesion features, thus facilitating the additional elucidation of the pathophysiology of EN and the search for promising treatments. 相似文献
10.
Gilbert Audira Petrus Siregar Kelvin H.-C. Chen Marri Jmelou M. Roldan Jong-Chin Huang Hong-Thih Lai Chung-Der Hsiao 《International journal of molecular sciences》2021,22(11)
Recently, medaka has been used as a model organism in various research fields. However, even though it possesses several advantages over zebrafish, fewer studies were done in medaka compared to zebrafish, especially with regard to its behavior. Thus, to provide more information regarding its behavior and to demonstrate the behavioral differences between several species of medaka, we compared the behavioral performance and biomarker expression in the brain between four medaka fishes, Oryzias latipes, Oryzias dancena, Oryzias woworae, and Oryzias sinensis. We found that each medaka species explicitly exhibited different behaviors to each other, which might be related to the different basal levels of several biomarkers. Furthermore, by phenomics and genomic-based clustering, the differences between these medaka fishes were further investigated. Here, the phenomic-based clustering was based on the behavior results, while the genomic-based clustering was based on the sequence of the nd2 gene. As we expected, both clusterings showed some resemblances to each other in terms of the interspecies relationship between medaka and zebrafish. However, this similarity was not displayed by both clusterings in the medaka interspecies comparisons. Therefore, these results suggest a re-interpretation of several prior studies in comparative biology. We hope that these results contribute to the growing database of medaka fish phenotypes and provide one of the foundations for future phenomics studies of medaka fish. 相似文献