Degradation of NiCr/CuNiMn/NiCr films on alumina substrates

This paper addresses the aging behaviour of NiCr/CuNiMn/NiCr triple layers on Al₂O₃ ceramics at temperatures up to 200°C for film thicknesses d0.5 μm. Investigations of the film structure and the increase of resistance and its temperature coefficient during the annealing process and studies of the dependence of this aging drift on both the film thickness and the storage temperature have been carried out. Furthermore, the film stress and the effect of substrate bending on resistance have been measured. The results can be explained by the irregular film structure (columns and small bridges between them), which causes stress and current concentrations as well as local creeping, cracking and oxidation processes in the micro-bridges. They are compared with such for structurally homogeneous films on silicon wafers.     

A mutational analysis of receptor binding sites of interleukin-1{beta}:differences in binding of human interleukin-1{beta} muteins to human and mouse receptors

The 3-D crystal structure of interleukin-1ß(IL-1ß)has been used to define its receptor binding surface by mutationalanalysis. The surface of IL-1ß was probed by site-directedmutagenesis. A total of 27 different IL-1ß muteinswere constructed, purified and analyzed. Receptor binding measurementson mouse and human cell lines were performed to identify receptoraffinities. IL-1ß muteins with modified receptor affinitywere evaluated for structural integrity by CD spectroscopy orX-ray crystallography. Changes in six surface loops, as wellas in the C- and N-termini, yielded muteins with lower bindingaffinities. Two muteins with intact binding affinities showed10- to 100-fold reduced biological activity. The surface regioninvolved in receptor binding constitutes a discontinuous areaof 1000 Å2 formed by discontinuous polypeptide chain stretches.Based on these results, a subdivision into two distinct localareas is proposed. Differences in receptor binding affinitiesfor human and mouse receptors have been observed for some muteins,but not for wild-type IL-1ß. This is the first timea difference in binding affinity of IL-1ß muteinsto human and mouse receptors has been demonstrated     

Modelling and analysis of the dynamics of a tilting three-wheeled vehicle

To understand the handling behaviour of a three-wheeled tilting vehicle, models of the vehicle with different level of detail, corresponding to specific fields of investigation, have been developed. Then the proposed kinematics of the three-wheeler are assessed and optimized with respect to desired dynamic properties by applying a detailed multibody system model. The partially unstable nature of the motion of the vehicle suggests the application of an analytically derived, simplified model, to allow for focusing on stability aspects and steady-state handling properties. These investigations reveal the necessity of employing a steer-by-wire control system to support the driver by stabilizing the motion of the vehicle. Thus, an additional basic vehicle model is derived for control design, and an energy-efficient control strategy is presented. Numerical simulation results demonstrate the dynamic properties of the optimized kinematics and the control system, approved by successful test runs of a prototype.     

The influence of text modality on learning with static and dynamic visualizations

In this study we investigated the influence of text modality on learning with static and dynamic visualizations in a dynamic domain, namely the physical principles underlying fish locomotion. A 2 × 2-design with type of visualization (static vs. dynamic) and text modality (spoken vs. written) as independent variables was used. Concerning learning outcomes, it was hypothesized that (1) learners presented with dynamic visualizations would outperform learners presented with static visualizations, (2) learners presented with spoken text would outperform learners presented with written text, and (3) an interaction between type of visualization and modality would occur: the superiority of dynamic over static visualizations was expected to be more pronounced for spoken compared to written text. Subjective cognitive load measures were assessed and expected to mirror the aforementioned pattern of learning outcomes in accordance with Cognitive Load Theory (i.e., higher extraneous cognitive load (ECL) related to lower learning outcomes). For transfer tasks, the first two hypotheses could be confirmed. However, there was no interaction. Moreover, ECL was rated higher by subjects when learning with static compared to dynamic visualizations, but there were no differences for ECL with respect to the text modality. The results are discussed within the framework of Cognitive Load Theory.     

The stability behaviour of hard material coatings on alloyed steel substrates

The stability behaviour of hard material coatings made by CVD on different alloyed and carbon steel substrates depends on the properties of both substrate and coating. SEM in-situ investigations on the tension loaded surface of bended samples may be used to observe crack nucleation and growth in brittle hard material coatings such as TiC, TiCN on low alloyed and carbon steels. From the crack distance distributions some important parameters of mechanical stability such as the threshold value of fracture σ_th, the Weibull-parameter β and the ratio of the strength distribution function F and a characteristic length D may be estimated. The threshold value for fracture in the coatings σ_th decreases with increasing coating thickness for all steel-coating combinations. The threshold value also decreases if a heat treatment is made on the steel-coating system. This is due to the relaxation of the internal stress in the coating. The mean strength of the TiC-coatings decreases and the strength variance (measured by the Weibull-parameter β) increases with increasing coating thickness and therefore the mechanical stability of coatings decreases with growing thickness. The ratio of the strength distribution function F and the characteristic distance between defects D as a measure of crack density depends on the deformation behaviour of the steel as well as on the strength and the defect structure of the coating.     

Coping strategies and psychological adjustment of couples presenting for IVF

The study was designed to examine the extent to which the psychological profiles of couples entering an IVF programme were influenced by evidence of previous fertility, the history of fertility investigations, the diagnosis made, and the coping strategies adopted. A sample of 152 couples was administered a number of standardized psychological instruments and a coping strategies questionnaire. They showed little variation from the normative range on the standardized measures. There was little evidence of differences between couples referred for primary or secondary infertility, between those with some evidence of fertility and those with none, or between different diagnostic groups. In relation to coping strategy, for women at least, taking direct action appears to be effective if it is associated with some degree of acceptance of one's position. For males, the picture is less clear, though direct action and acceptance again appear to be effective coping strategies.     

Transient stability analysis in power systems with multiple simultaneous failts

Contents A generalized method for performing the transient stability analysis in electrical power systems, which are subjected to simultaneous unsymmetrical conditions in the network, is developed. The unsymmetrical nature of the network may be due to any arbitrary combination of unsymmetrical short circuits and circuit breaker switchings. A computer program based on the method has also been written and the results obtained in the analyses of a sample system are also included.

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Transient-Stabilitätsuntersuchungen in Verbundnetzen mit mehrfachen Simultanfehlern

Übersicht Es wurde eine verallgemeinerte Methode zur Untersuchung der transienten Stabilität in elektrischen Verbundsystemen entwickelt, die es gestattet, simultane unsymmetrische Fehler in diesem Netz zu berücksichtigen. Hierbei ist es zulässig, daß jede Kombination von symmetrischen Kurzschlüssen und unsymmetrischen Unterbrechungen gleichzeitig auftreten können. Ein Programm, das nach dieser Methode arbeitet, wurde erstellt und die Ergebnisse der Durchrechnung eines Musterbeispiels mitgeteilt.