用通用两点法测量明渠流速

一、前言测出一条河流的流量,通常是在垂直于水流方向的不同位置上测出其深度平均流速,再将其进行积分,然后即可求出流量。一般采取的步骤是,从垂直于水面方向测量0.2D和0.8D处的流速来求出其深度平均值,或测出0.6D处的流速,其中D为整个水流深度。有时,需要测量除0.2D和0.8D位置以外水深处的流速,例如,间歇流量计用其设在固定垂直位置上的两个探测器来连续监测流速。随着总水深的改变,其相对测试位置亦随之而     

Preparation and storage stability of dried salted mutton

Minced (8 or 18 mm plate) mutton with salt (25%) and sorbate (0·4%) was pressed into cakes about 11 cm in diameter and 3 cm high. The cakes were partially dried in an air oven at 40°C for 48 h to a water activity of about 0·75. The cakes were packed, either in vacuo or in air, and stored at 30 or 2°C for up to 60 days. Objective assessment of quality showed that these dried salted meats can be kept for up to 60 days at 30°C with little loss of textural or nutritional quality although some fading, due to haemoprotein breakdown, occurs. Packaging in vacuum, however, minimises this loss of colour and would be recommended for centralised manufacture prior to distribution in developing, tropical countries.     

High-frequency differential piezoelectric photoacoustic investigation of ion-implanted (100) silicon wafers via laser beam position modulation

An exploratory application of position-modulation photoacoustic imaging of ion-implanted (100)-oriented Si wafers was undertaken to assess its potential as a diagnostic probe in semiconductor processing. Wafer scans were performed using acoustooptic modulation of a 1.06-mum Nd(3+):YAG laser beam up to 0.2 MHz with piezoelectric photoacoustic detection. Sensitivity ranges to ion-implanted parameters (ionic species and fluences) were studied and the capability of the technique to monitor processing-induced damage was established. Results indicate that position-modulated photoacoustic detection offers higher sensitivity than single-beam photothermal imaging and has distinct advantages over other analytical techniques.     

不锈钢表面超薄铜层的激光熔覆

采用ＣＯ２激光器在３１６Ｌ不锈钢表面获得了超薄的铜熔覆层,文中分析和讨论了激光熔覆工艺参数加激光功率,熔覆速度,离焦量以及送粉率等对熔覆层质量的影响,提出了熔覆工艺的优化方法,使铜层的熔覆厚度可控制在１００μｍ之内,稀释率小于１０％以及很小的热变形。     

A new combined computational and NMR-spectroscopical strategy for the identification of additional conformational constraints of the bound ligand in an aprotic solvent

This study documents the feasibility of switching to an aprotic medium in sugar receptor research. The solvent change offers additional insights into mechanistic details of receptor--carbohydrate ligand interactions. If a receptor retained binding capacity in an aprotic medium, solvent-exchangeable protons of the ligand would not undergo transfer and could act as additional sensors, thus improving the level of reliability in conformational analysis. To probe this possibility, we first focused on hevein, the smallest lectin found in nature. The NMR-spectroscopic measurements verified complexation, albeit with progressively reduced affinity by more than 1.5 orders of magnitude, in mixtures of up to 50% dimethyl sulfoxide (DMSO). Since hevein lacks the compact beta-strand arrangement of other sugar receptors, such a structural motif may confer enhanced resistance to solvent exchange. Two settings of solid-phase activity assays proved this assumption for three types of alpha- and/or beta-galactoside-binding proteins, that is, a human immunoglobulin G (IgG) subfraction, the mistletoe lectin, and a member of the galectin family of animal lectins. Computer-assisted calculations and NMR experiments also revealed no conspicuous impact of the solvent on the conformational properties of the tested ligands. To define all possible nuclear Overhauser effect (NOE) contacts in a certain conformation and to predict involvement of exchangeable protons, we established a new screening protocol applicable during a given molecular dynamics (MD) trajectory and calculated population densities of distinct contacts. Experimentally, transferred NOE (tr-NOE) experiments with IgG molecules and the disaccharide Gal'alpha1-3Galbeta1-R in DMSO as solvent disclosed that such an additional crosspeak, that is, Gal'OH2--GalOH4, was even detectable for the bound ligand under conditions in which spin diffusion effects are suppressed. Further measurements with the plant lectin and galectins confirmed line broadening of ligand signals and gave access to characteristic crosspeaks in the aprotic solvent and its mixtures with water. Our combined biochemical, computational, and NMR-spectroscopical strategy is expected to contribute notably to the precise elucidation of the geometry of ligands bound to compactly folded sugar receptors and of the role of water molecules in protein--ligand (carbohydrate) recognition, with relevance to areas beyond the glycosciences.     

Multiple isotope effects on the acyl group transfer reactions of amides and esters

Acyl group transfer reactions, especially those to amides and esters, are important in biochemistry. Multiple kinetic isotope effects for the atoms at the reactive center of these molecules have provided the most detailed bonding picture of the transition state to date. These kinetic isotope effect studies are reviewed for several reactions of formamide, methyl benzoate, and methyl formate. In these cases all the evidence is consistent with a stepwise mechanism, involving tetrahedral intermediates. In the case of p-nitrophenyl acetate, the change to an excellent leaving group causes the tetrahedral intermediates to become kinetically unstable; the kinetic isotope effects are best fitted to a concerted mechanism.     

The magnetic-distortion probe: velocimetry in conducting fluids

A new type of velocimeter, capable of local velocity measurements in conducting fluids, is introduced. The principle of the "magnetic-distortion probe" is based on the measurement of the induced magnetic field by the flow of a conducting fluid in the vicinity of a localized magnetic field. The new velocimeter has no moving parts, and can be enclosed in a sealed cap, easing the implementation in harsh environments, such as liquid metals. The proposed method allows one to probe both the continuous part and fluctuations of the velocity, the temporal and spatial resolution being linked to the actual geometric configuration of the probe. A prototype probe has been tested in a gallinstan pipe flow and in a fully turbulent flow of liquid gallium generated by the counter rotation of two coaxial impellers in a cylinder. The signals have been compared to a reference potential probe and show very good agreement both for time-averaged velocities and turbulent fluctuations. The prototype is shown to detect motion from a few cm s(-1) to a few m s(-1). Moreover, the use of the magnetic-distortion probe with large-scale applied magnetic field is discussed.     

Efficient tracking of the dominant eigenspace of a normalized kernel matrix

Various machine learning problems rely on kernel-based methods. The power of these methods resides in the ability to solve highly nonlinear problems by reformulating them in a linear context. The dominant eigenspace of a (normalized) kernel matrix is often required. Unfortunately, the computational requirements of the existing kernel methods are such that the applicability is restricted to relatively small data sets. This letter therefore focuses on a kernel-based method for large data sets. More specifically, a numerically stable tracking algorithm for the dominant eigenspace of a normalized kernel matrix is proposed, which proceeds by an updating (the addition of a new data point) followed by a downdating (the exclusion of an old data point) of the kernel matrix. Testing the algorithm on some representative case studies reveals that a very good approximation of the dominant eigenspace is obtained, while only a minimal amount of operations and memory space per iteration step is required.     

Magnetic quadrupole doublet focusing system for high energy ions

A high energy focused ion beam microprobe using a doublet arrangement of short magnetic quadrupole lenses was used to focus 1-3 MeV protons to spot sizes of 1x1 microm2 and 1-4.5 MeV carbon and silicon ion beams to spot sizes of 1.5x1.5 microm2. The results presented clearly demonstrate that this simple doublet configuration can provide high energy microbeams for microanalysis and microfabrication applications.