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Giordano C Chiesa R Sandrini E Cigada A Giavaresi G Fini M Giardino R 《Journal of materials science. Materials in medicine》2005,16(12):1221-1229
The present study assessed in vitro the short-term cellular response to surface physico-chemical properties of a new, purposed bioactive surface treatment called
BioSparkTM performed on simply machined and on sand-blasted titanium. Material characterisation was carried out using scanning electron
microscopy, energy dispersion spectroscopy, laser profilometry, and thin film X-ray diffraction. The in vitro biological study showed a suitable cellular response with adhesion and spreading level comparable for all the tested specimens.
The proliferation analysis demonstrated that all the surfaces successfully supported cellular colonisation; in particular,
higher cellular proliferation activity was observed on the BioSparkTM-treated materials, with values higher than machined titanium. The results suggest that the BioSparkTM treatment represents a smart way to enhance osteoblastic cellular colonisation and thus improve osteointegration processes
of machined and sandblasted titanium for orthopaedic and dental implants. 相似文献
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