The rank and kernel of extended 1-perfect /spl Zopf//sub 4/-linear and additive non-/spl Zopf//sub 4/-linear codes

A binary extended 1-perfect code of length n + 1 = 2/sup t/ is additive if it is a subgroup of /spl Zopf//sub 2//sup /spl alpha// /spl times/ /spl Zopf//sub 4//sup /spl beta//. The punctured code by deleting a /spl Zopf//sub 2/ coordinate (if there is one) gives a perfect additive code. 1-perfect additive codes were completely characterized and by using that characterization we compute the possible parameters /spl alpha/, /spl beta/, rank, and dimension of the kernel for extended 1-perfect additive codes. A very special case is that of extended 1-perfect /spl Zopf//sub 4/-linear codes.     

Tumor necrosis factor alpha interferes with the cell cycle of normal and papillomavirus-immortalized human keratinocytes

We have shown that normal and human papillomavirus (HPV) type 16 immortalized human foreskin keratinocytes are growth inhibited by tumor necrosis factor alpha (TNF-alpha), whereas HPV-18- and SV40-immortalized keratinocytes are resistant to this cytokine (1). In this report, we investigated the expression of mitotic regulatory proteins, such as cyclin A, cyclin B, and p34cdc2. After exposure to TNF-alpha, normal and HPV-16-immortalized cells exhibited a dramatic decrease in the expression of these proteins. In contrast, no alteration in the levels of these proteins was observed after treatment of the resistant cell lines, as well as two HPV-positive cervical carcinoma cell lines. Expression of cyclin E does not seem to be modulated by TNF-alpha in any of the cells tested. On the other hand, cyclin D1, expression is slightly increased in normal keratinocytes and in the HPV-16-immortalized cells, whereas no alteration was observed in the HPV-18-transfected cells. The phosphorylation state of pRb correlated with cell growth; sensitive cells, which accumulate in G0-G1, after exposure to TNF-alpha, exhibited an accumulation of hypophosphorylated pRb, whereas no effect on pRb phosphorylation was observed for HPV-18-immortalized cells. These results clearly correlate with TNF-alpha-induced growth arrest in G0-G1.     

Single-frequency, single-knob tuning of a CW color center laser

We describe a simple way to achieve CW single-frequency laser operation with a grating as the sole tuning element. It is Shown, both experimentally and theoretically, that by proper choice of cavity parameters, the competing hole burning modes can be completely suppressed. Experiments to demonstrate the theoretical calculations were carried out in a CW color center laser using Tl⁰(1) centers. Linewidths of 0.01 cm^-1were obtained and this figure can probably be much improved by proper cavity stabilization. The method can be readily extended to any compact gain medium.     

Analysis of the essential oil of Mexican oregano (Lippia graveolens HBK)

The composition of the volatile oil of Mexican oregano (Lippia graveolens HBK) isolated by steam distillation was investigated by means of column chromatography, gas chromatography and mass spectrometry. A total of 33 components were identified including 22 hydrocarbons, 4 alcohols, 4 ethers, 2 phenols and 1 ketone. Of the 33 components observed in the present study 7 were identified in Mexican oregano for the first time.     

Ranking Pages by Topology and Popularity within Web Sites

We compare two link analysis ranking methods of web pages in a site. The first, called Site Rank, is an adaptation of PageRank to the granularity of a web site and the second, called Popularity Rank, is based on the frequencies of user clicks on the outlinks in a page that are captured by navigation sessions of users through the web site. We ran experiments on artificially created web sites of different sizes and on two real data sets, employing the relative entropy to compare the distributions of the two ranking methods. For the real data sets we also employ a nonparametric measure, called Spearman's footrule, which we use to compare the top-ten web pages ranked by the two methods. Our main result is that the distributions of the Popularity Rank and Site Rank are surprisingly close to each other, implying that the topology of a web site is very instrumental in guiding users through the site. Thus, in practice, the Site Rank provides a reasonable first order approximation of the aggregate behaviour of users within a web site given by the Popularity Rank.     

Stochastic molecular descriptors for polymers. 4. Study of complex mixtures with topological indices of mass spectra spiral and star networks: The blood proteome case

The Quantitative Structure-Property Relationships (QSPRs) based on Graph or Network Theory are important for predicting the properties of polymeric systems. In the three previous papers of this series (Polymer 45 (2004) 3845-3853; Polymer 46 (2005) 2791-2798; and Polymer 46 (2005) 6461-6473) we focused on the uses of molecular graph parameters called topological indices (TIs) to link the structure of polymers with their biological properties. However, there has been little effort to extend these TIs to the study of complex mixtures of artificial polymers or biopolymers such as nucleic acids and proteins. In this sense, Blood Proteome (BP) is one of the most important and complex mixtures containing protein polymers. For instance, outcomes obtained by Mass Spectrometry (MS) analysis of BP are very useful for the early detection of diseases and drug-induced toxicities. Here, we use two Spiral and Star Network representations of the MS outcomes and defined a new type of TIs. The new TIs introduced here are the spectral moments (π_k) of the stochastic matrix associated to the Spiral graph and describe non-linear relationships between the different regions of the MS characteristic of BP. We used the MARCH-INSIDE approach to calculate the π_k(SN) of different BP samples and S2SNet to determine several Star graph TIs. In the second step, we develop the corresponding Quantitative Proteome-Property Relationship (QPPR) models using the Linear Discriminant Analysis (LDA). QPPRs are the analogues of QSPRs in the case of complex biopolymer mixtures. Specifically, the new QPPRs derived here may be used to detect drug-induced cardiac toxicities from BP samples. Different Machine Learning classification algorithms were used to fit the QPPRs based on π_k(SN), showing J48 decision tree classifier to have the best performance. These results suggest that the present approach captures important features of the complex biopolymers mixtures and opens new opportunities to the application of the idea supporting classic QSPRs in polymer sciences.     

Grand theories of personality cannot be integrated.

Comments on the original article "A New Big Five: Fundamental Principles for an Integrative Science of Personality," by Dan P. McAdams and Jennifer L. Pals (see record 2006-03947-002). McAdams and Pals (April 2006) presented a new model to integrate the field of personality psychology. Cultural and evolutionary factors interact with an individual's basic traits, characteristic adaptations, and life narratives, which in turn are linked to roles, demands, and behaviors. The current authors welcome McAdams and Pals's (2006) model for providing a way to integrate much of the previously disparate empirical findings in personality psychology. However, the current authors also think that McAdams and Pals (2006) overstated the inclusiveness of the model, and more generally, the current authors dispute their assertion that the grand theories of personality can be integrated within a single model. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Study of the nozzle flow in a cross-flow turbine

An investigation of the flow inside the nozzle of a Cross-Flow turbine, which is a hydraulic turbine where the rectangular water jet issuing from the nozzle crosses the rotor blades twice, is presented here. Part of the investigation consisted in the experimental measurement of the static pressure distribution on the inside walls of two different nozzle configurations, both with the nozzle mounted alone and in the presence of a rotor. The tests performed in the presence of a rotor included the measurement of efficiency and covered a wide range of working conditions around the best efficiency point. The analysis of the results obtained in this way give us an indication of the influence of the turbine non-dimensional volume flow rate on the flow inside the nozzle and the way it affects the reaction degree of the machine and its efficiency level. Although most of the tests were carried out with a 25-blade rotor, one of the analysed nozzle configurations (that with an inside vane) was also tested with a 10-blade rotor, permitting the assessment of the effect the number of blades has on the flow in the nozzle.The flow inside the nozzle with no inside vane was numerically analysed using a method based on a Schwarz-Christoffel conformal transformation of variables. The numerical results show a fair agreement with the experimental data collected when the rotor was not present. A qualitative discussion of some of the losses occurring in the nozzle is advanced based on the computer results, and its conclusions are used for explaining the poor performance of the nozzle with no inside vane.     

Hull-less Barley Varieties: Storage Proteins and Amino Acid Distribution in Relation to Nutritional Quality

Barley (Hordeum vulgare L.) has had an important impact on human nutrition. Hull-less barley is a genetically improved type that has been widely used in recent years. Six Brazilian hull-less barley varieties (IAC-IBON 214-82; IAC 8612-421; IAC 8501-31; IAC 8501-12; IAPAR 39-ACUMAI; IAC 8501-22) were analyzed for storage protein constituents, amino acid contents, and similarity among the hull-less barley varieties. Albumins, globulins, prolamins I and II, and glutelins were extracted and separated by SDS-PAGE. The total protein amino acid contents of the flour were also determined for each variety by TLC and HPLC. Variations in intensity and appearance and disappearance of protein bands were observed among the varieties suggesting genetic variability. However, the amino acid profile did not indicate any major variations in the amino acid concentrations. The high lysine and threonine total concentrations detected in the seeds of the hull-less barley varieties encouraged an investigation into the regulation of amino acid metabolism and storage protein synthesis.