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排序方式: 共有388条查询结果,搜索用时 15 毫秒
1.
Juana Maria de Lourdes Medina-Contreras Patrick Mailloux-Salinas Juventino III Colado-Velazquez Norma Leticia Gomez Viquez Gómez-Viquez Rodrigo Velázquez-Espejel Ana del Carmen Susunaga-Notario David Julian Arias-Chávez Guadalupe Bravo 《Journal of the science of food and agriculture》2020,100(7):3212-3219
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3.
H Moffet CL Richards F Malouin G Bravo G Paradis 《Canadian Metallurgical Quarterly》1994,75(4):415-426
The efficacy of an early, intensive, supervised rehabilitation program to accelerate knee strength recovery in the first 3 weeks postmeniscectomy by arthroscopy was evaluated using a randomized controlled trial design. The maximal voluntary isokinetic strength of 31 men, randomly allocated to either a treatment (EXP) or a control (CTL) group, was measured twice by a blind rater: preoperatively (pretest) and 3 weeks postsurgery (posttest), using a computer-controlled Kin-Com dynamometer (Chattecx Corporation, Chattanooga, TN). Strength deficits of the operated leg at the pretest and posttest were established in percent of the values obtained for the sound leg at the pretest. In the interval between the surgery and the posttest, the patients of the EXP group (n = 15) received nine supervised treatments combined to home exercises whereas patients of the control group (n = 16) had no specific physiotherapy treatment but were given instructions in postsurgical management and prescribed exercises by the orthopedic surgeons. Patients of the EXP group had better knee extensor strength recovery than patients of the CTL group (ANCOVA, p < 0.001). The size of the strength difference (3 weeks postsurgery) between EXP and CTL subgroups (n = 8) matched according to preoperative deficits was as large as 26% and the residual deficits of the untreated patients were two to three times larger than those of the treated patients. The results of this study highlight the importance of instituting an early intensive and supervised rehabilitation program, especially for workers returning to a strenuous job requiring good knee extensor muscle function. 相似文献
4.
L Bravo RJ Monté V Alfonso N Cabrera M Gómez R Hernández B García 《Canadian Metallurgical Quarterly》1995,47(3):215-216
One hundred and fifty-five strains of Aeromonas isolated in the stools of children under 5 years presenting with acute diarrheal disease were studied. Using the Aerokey II system for the identification of species, 47 strains were identified as Aeromonas caviae, 58 as Aeromonas hydrophila, 23 as Aeromonas veronii biovar sobria, 14 as Aeromonas trota, 9 as Aeromonas veronii biovar veronii, 2 as Aeromonas jandaei and 2 as Aeromonas shubertii, Emphasis is placed on the advantages of this method which allowed for the classification of new species not identified previously in our country. 相似文献
5.
Julia Peas-Martínez María N. Barrachina Ernesto Jos Cuenca-Zamora Gins Luengo-Gil Susana Beln Bravo Eva Caparrs-Prez Raúl Teruel-Montoya Jos Eliseo-Blanco Vicente Vicente ngel García Irene Martínez-Martínez Francisca Ferrer-Marín 《International journal of molecular sciences》2021,22(4)
Exosomes are extracellular vesicles that contain nucleic acids, lipids and metabolites, and play a critical role in health and disease as mediators of intercellular communication. The majority of extracellular vesicles in the blood are platelet-derived. Compared to adults, neonatal platelets are hyporeactive and show impaired granule release, associated with defects in Soluble N-ethylmaleimide-sensitive fusion Attachment protein REceptor (SNARE) proteins. Since these proteins participate in biogenesis of exosomes, we investigated the potential differences between newborn and adult plasma-derived exosomes. Plasma-derived exosomes were isolated by ultracentrifugation of umbilical cord blood from full-term neonates or peripheral blood from adults. Exosome characterization included size determination by transmission electron microscopy and quantitative proteomic analysis. Plasma-derived exosomes from neonates were significantly smaller and contained 65% less protein than those from adults. Remarkably, 131 proteins were found to be differentially expressed, 83 overexpressed and 48 underexpressed in neonatal (vs. adult) exosomes. Whereas the upregulated proteins in plasma exosomes from neonates are associated with platelet activation, coagulation and granule secretion, most of the underexpressed proteins are immunoglobulins. This is the first study showing that exosome size and content change with age. Our findings may contribute to elucidating the potential “developmental hemostatic mismatch risk” associated with transfusions containing plasma exosomes from adults. 相似文献
6.
Two samples of poly(diethoxyphosphazene) (PDEP) having very different molecular weights have been studied by viscometry and size exclusion chromatography in THF solution. The results obtained, together with light scattering data of these samples, allow the calculation of the Mark-Houwink constants a=0.65 and K=2.5 10-4 in THF at 25°C. The method of calculation employed takes into account the great polydispersity of the samples. The characteristic ratio of the unperturbed dimensions was also calculated giving Cn = r2o/n2 18, a value slightly higher than those previously reported for poly(dihexoxyphosphazene), Cn13 and poly (dichlorophosphazene), Cn13.5. 相似文献
7.
Jesús Gallardo Crescencio Bravo Miguel A. Redondo Juan de Lara 《Journal of Visual Languages and Computing》2013,24(1):10-23
Over the last two decades, Collaborative Systems have become increasingly popular thanks to the many advances made in networks, communications and software tools. Within this field, Collaborative Modeling Systems apply the collaborative paradigm to the construction of (often visual) models, where users build diagrams from building blocks and the relationships between them. In these kinds of applications, the work is usually arranged into sessions, with the definition of some kind of time organization between those sessions. This organization is known as a collaboration protocol. Unfortunately, it is not usually easy to define these protocols, and many applications do not allow users to make any use of them.In an effort to overcome these difficulties, in this paper we propose a visual language for defining collaboration protocols for these systems. As such, in our language, sessions, artifacts and the transformations between them can be specified visually, and different coordination relationships (such as fork and join) can be defined. The visual language is included in a development method for collaborative systems that take advantage of the Eclipse platform in order to develop model-driven graphical editors that are enhanced with collaboration capabilities. 相似文献
8.
David Bravo Katherine Zepeda-Morales Carola J. Maturana Jeffri S. Retamal Alejandro Hernndez Teresa Pelissier Rafael Barra Patricio Sez-Briones Hctor Burgos Luis Constandil 《International journal of molecular sciences》2022,23(12)
Pannexin 1 (Panx1) is involved in the spinal central sensitization process in rats with neuropathic pain, but its interaction with well-known, pain-related, ligand-dependent receptors, such as NMDA receptors (NMDAR) and P2X7 purinoceptors (P2X7R), remains largely unexplored. Here, we studied whether NMDAR- and P2X7R-dependent nociceptive signaling in neuropathic rats require the activation of Panx1 channels to generate spinal central sensitization, as assessed by behavioral (mechanical hyperalgesia) and electrophysiological (C-reflex wind-up potentiation) indexes. Administration of either a selective NMDAR agonist i.t. (NMDA, 2 mM) or a P2X7R agonist (BzATP, 150 μM) significantly increased both the mechanical hyperalgesia and the C-reflex wind-up potentiation, effects that were rapidly reversed (minutes) by i.t. administration of a selective pannexin 1 antagonist (10panx peptide, 300 μM), with the scores even reaching values of rats without neuropathy. Accordingly, 300 μM 10panx completely prevented the effects of NMDA and BzATP administered 1 h later, on mechanical hyperalgesia and C-reflex wind-up potentiation. Confocal immunofluorescence imaging revealed coexpression of Panx1 with NeuN protein in intrinsic dorsal horn neurons of neuropathic rats. The results indicate that both NMDAR- and P2X7R-mediated increases in mechanical hyperalgesia and C-reflex wind-up potentiation require neuronal Panx1 channel activation to initiate and maintain nociceptive signaling in neuropathic rats. 相似文献
9.
Antonio J. Suárez Fábrega José Manuel Bravo Caro Pedro J. Abad Herrera Rafael M. Gasca 《International Journal of Adaptive Control and Signal Processing》2014,28(12):1299-1324
In this paper, a new data‐driven fault‐detection method is proposed. This method is based on a new nonparametric system identification approach, which constitutes the principal contribution to this work. The fault‐detection method is a parametric model‐free approach that can be applied to nonlinear systems that work at various operating points. Not only can the fault‐detection process be applied to the steady state of each operating point, but it can also be applied to the transient state resulting from a change in the operating point. In order to detect faults, the proposed method uses an interval predictor based on bounded‐error techniques. The utilization of techniques based on bounded error enables system uncertainties to be included in an explicit way. This in turn leads to the possibility of obtaining interval predictions of the behaviour of the system, which include information on the reliability of the prediction itself. In order to show the effectiveness of the fault‐detection method, two examples are presented: in the form of a simulated process (counter‐flow shell‐and‐tube heat‐exchanger system) and an example of a real application (two‐tanks system). A comparison with two fault‐detection methods has also been included. Copyright © 2013 John Wiley & Sons, Ltd. 相似文献
10.
We consider a Fermion in the presence of a rotating BH immersed in a universe with a positive cosmological constant. After presenting a rigorous classification of the number and type of the horizons, we adopt the Carter tetrad to separate the aforementioned equation into radial and angular equations. We show how the Chandrasekhar ansatz leads to the construction of a symmetry operator that in the limit of a vanishing cosmological constant reproduces the square root of the squared total angular momentum operator for a Dirac particle in the Kerr metric. Furthermore, we prove that the the spectrum of the angular operator is discrete and consists of simple eigenvalues, and by means of the functional Bethe ansatz method we also derive a set of necessary and sufficient conditions for the angular operator to have polynomial solutions. Finally, we show that there exist no bound states for the Dirac equation in the non-extreme case. 相似文献