Efficient compensation for frequency-dependent errors in analog reconstruction filters used in IQ modulators

In a direct-conversion transmitter system, the nonideal transfer characteristics of practical analog subsystems can have significant adverse effects on the performance of the transmitter system. While a significant body of research exists on correcting static errors (including gain imbalance, phase errors, and DC offsets) in the analog subsystems, relatively little attention has been paid to the impact of nonideal frequency-dependent characteristics in the analog reconstruction filters that are employed in direct-conversion structures. This paper presents a new computationally efficient and numerically robust method for automatic digital compensation for nonideal frequency-dependent characteristics in the signal reconstruction filters of a quadrature (IQ) modulator structure. The new compensation technique is used in conjunction with existing compensation approaches that compensate for static errors.     

The natural killer cell receptor specific for HLA-A allotypes: a novel member of the p58/p70 family of inhibitory receptors that is characterized by three immunoglobulin-like domains and is expressed as a 140-kD disulphide-linked dimer

Human natural killer (NK) cells express inhibitory receptors that are specific for different groups of HLA-C or HLA-B alleles. The majority of these receptors belong to the immunoglobulin (Ig) superfamily and are characterized by two or three extracellular Ig-like domains. Here we describe a novel inhibitory NK receptor that is specific for a group of HLA-A alleles. The HLA-A3-specific NK cell clone DP7 has been used for mice immunization. Two mAbs, termed Q66 and Q241, bound to the immunizing clone and stained only a subset of NK cell populations or clones. Among Q66 mAb-reactive clones, we further selected those that did not express any of the previously identified HLA-class I-specific NK receptors. These clones did not lyse HLA-A3+ (or -A11+) target cells, but lysis of these targets could be detected in the presence of Q66 or Q241 mAbs. On the other hand, target cells expressing other HLA-A alleles, including -A1, -A2, and -A24, were efficiently lysed. Moreover, none of the HLA-C or HLA-B alleles that were tested exerted a protective effect. Q66+, but not Q66- NK cell clones, expressed messenger RNA coding for a novel 3 Ig domain protein homologous to the HLA-C (p58) and HLA-B (p70) receptors. The corresponding cDNA (cl.1.1) was used to generate transient and stable transfectants in COS7 and NIH3T3 cell lines, respectively. Both types of transfectants were specifically stained by Q66 and Q241 mAbs. Since the cytoplasmic tail of Q66-reactive molecules was at least 11 amino acid longer than the other known p58/p70 molecules, we could generate an antiserum specific for the COOH-terminus of Q66-reactive molecules, termed PGP-3. PGP-3 immunoprecipitated, only from Q66+ NK cells, molecules displaying a molecular mass of 140 kD, under nonreducing conditions, which resolved, under reducing conditions, in a 70-kD band. Thus, differently from the other p58/p70 receptors, Q66-reactive molecules appear to be expressed as disulphide-linked dimers and were thus termed p140. The comparative analysis of the amino acid sequences of p58, p70, and p140 molecules revealed the existence of two cysteins proximal to the transmembrane region, only in the amino acid sequence of p140 molecules.     

Iterative method for the design of DFT filter Bank

Multirate adaptive filters have numerous advantages such as low computational load, fast convergence, and parallelism in the adaptation. Drawbacks when using multirate processing are mainly related to aliasing and reconstruction effects. These effects can be minimized by introducing appropriate problem formulation and employing sophisticated optimization techniques. In this paper, we propose a formulation for the design of a filter bank which controls the distortion level for each frequency component directly and minimizes the inband aliasing and the residual aliasing between different subbands. The advantage of this problem formulation is that the distortion level can be weighted for each frequency depending on the particular practical application. A new iterative algorithm is proposed to optimize simultaneously over both the analysis and the synthesis filter banks. This algorithm is shown to have a unique solution for each iteration. For a fixed distortion level, the proposed algorithm yields a significant reduction in both the inband aliasing and the residual aliasing levels compared to existing methods applied to the numerical examples.     

A new approach to the optimization of robust antenna arrayprocessors

The authors present a method for solving a class of optimization problems with nonsmooth constraints. In particular, they apply the method to the design of narrowband minimum-power antenna array processors which are robust in the presence of errors such as array element placement, look direction misalignment, and frequency offset. They first show that the constrained minimum power problem has a unique global minimum provided that the constraint set is nonempty. Then it is shown how the design problem derived directly from considerations of the sensitivity of the antenna array processor to errors can be transformed into a quadratic programming problem with linear inequality constraints which can be solved efficiently by the standard active set strategy. They also present numerical results for two types of nonsmooth constraints developed to provided robustness. These results confirm the effectiveness of the method     

Digital Laguerre filter design with maximum passband-to-stopband energy ratio subject to peak and Group delay constraints

In this paper, we formulate a general design of transversal filter structures with maximum relative passband-to-stopband energy ratio subject to complex frequency response constraints in the passband and the stopband as well as additional constraints such as constraints. These constraints are important for applications where the suppression of noise at certain frequencies are important. Additional constraints are introduced allowing approximately linear phase and constant group delay in the passband. For a given set of basis functions, the design problem can be formulated as a semi-infinite quadratic optimization problem in the filter coefficients, which are the decision variables to be optimized. In this paper, we focus on the design of digital Laguerre filter and digital finite impulse response (FIR) filter structures. A modified bridging algorithm is developed for searching for the optimum pole of the Laguerre filters. Design examples are given to demonstrate the effectiveness of the proposed algorithm.     

Shear mode coupling and tilted grain growth of A1N thin films in BAW resonators.

Polycrystalline A1N thin films were deposited by RF reactive magnetron sputtering on Pt(111)/Ti electrode films. The substrates were tilted by an angle ranging from 40 degrees to 70 degrees with respect to the target normal. A low deposition temperature and a high sputter gas pressure were found ideal for tilted growth. The resulting grain tilt angle amounts to about half the substrate tilt angle. For coupling evaluation, 5 GHz solidly mounted resonator structures have been realized. The tilted grain A1N films exhibited a permittivity in the 9.5-10.5 range and loss tangent of 0.3%. Two shear modes as well as the longitudinal mode could be clearly identified. The coupling coefficient k2(eff) of the fundamental thickness shear mode (TS0) was found to be about 0.5%, which is compatible with a c-axis tilt of about 6 degrees.     

Derivative constrained optimum broad-band antenna arrays

The optimization problem corresponding to the design of a presteered broadband processor with maximally flat second-order spatial response in the look direction is discussed. The constraints corresponding to necessary and sufficient conditions for second-order flatness are presented. The nonlinearly constrained optimization approach is unable to consistently locate the global minimum. An approach to solving this problem that essentially converts the nonconvex optimization problem into a parameterized set of convex problems is presented. In the case of 2-D scenarios, the global optimum is determined by finding the roots of a cubic function. The characteristics of the constraints, including the minimum number required and the dependence on the choice of coordinate systems, are examined     

mmr, a Mycobacterium tuberculosis gene conferring resistance to small cationic dyes and inhibitors

The mmr gene, cloned from Mycobacterium tuberculosis, was shown to confer to Mycobacterium smegmatis resistance to tetraphenylphosphonium (TPP), erythromycin, ethidium bromide, acriflavine, safranin O, and pyronin Y. The gene appears to code for a protein containing four transmembrane domains. Studies of [3H]TPP intracellular accumulation strongly suggest that the resistance mediated by the Mmr protein involves active extrusion of TPP.     

Stability of Decision Feedback Inverses

The method of inversion of linear discrete time systems utilizing quantized feedback is examined, and a stability concept is developed. The application in mind is decision feedback equalization (DFE). Sets of necessary conditions and sufficient conditions for stability are derived. A lower bound for the probability of recovery from error, and an upper bound for the mean recovery time are obtained. It is suggested that a stability index for each system could be defined. The bounds derived do not depend on the nature of the noise or the channel impulse response except through its length.