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1.
Dibakar Sen 《Computer aided design》2012,44(1):15-28
Digital human modeling (DHM) involves modeling of structure, form and functional capabilities of human users for ergonomics simulation. This paper presents application of geometric procedures for investigating the characteristics of human visual capabilities which are particularly important in the context mentioned above. Using the cone of unrestricted directions through the pupil on a tessellated head model as the geometric interpretation of the clinical field-of-view (FoV), the results obtained are experimentally validated. Estimating the pupil movement for a given gaze direction using Listing’s Law, FoVs are re-computed. Significant variation of the FoV is observed with the variation in gaze direction. A novel cube-grid representation, which integrated the unit-cube representation of directions and the enhanced slice representation has been introduced for fast and exact point classification for point visibility analysis for a given FoV. Computation of containment frequency of every grid-cell for a given set of FoVs enabled determination of percentile-based FoV contours for estimating the visual performance of a given population. This is a new concept which makes visibility analysis more meaningful from ergonomics point-of-view. The algorithms are fast enough to support interactive analysis of reasonably complex scenes on a typical desktop computer. 相似文献
2.
SiO2–CaO–Na2O–P2O5–ZrO2 based bioactive glasses with different compositions of SiO2 and yttrium stabilized ZrO2 were prepared by the conventional melt quenching technique. The effects on the chemical–mechanical properties of bioactive glasses due to the addition of ZrO2 by replacing SiO2 were investigated. Microstructure and phase behavior were studied by scanning electron microscopy, energy-dispersive spectroscopy, and X-ray diffraction analysis. Compressive strength, porosity, Vickers hardness, and Young’s modulus were measured as mechanical properties. Bioactivity and cell viability were investigated by immersion in simulated body fluid and MTT assay analysis. Osteosarcoma cell proliferation on the specimen surfaces was examined by confocal laser scanning microscopy. The results showed that replacing SiO2 with ZrO2 helps the bioactive glass to be completely vitrified at comparatively lower sintering temperature than conventional Bioglass®. The mechanical properties were also improved without compromising biocompatibility. Bioactive glass containing 10 wt% ZrO2 and 35 wt% SiO2 showed compressive strength of 399.71 MPa, Young's modulus of 22.3 GPa, Vicker’s hardness of 502.54 HV, and porosity of 26 vol%. 相似文献
3.
4.
Rajesh B. Gujar Parveen K. Verma Bholanath Mahanty Seraj A. Ansari Dibakar Goswami 《分离科学与技术》2020,55(14):2560-2569
ABSTRACT Solvent extraction studies were performed to understand the extraction behavior of Np4+ and NpO2 2+ from acidic feeds with CMPO (octyl (phenyl)-N,N-diisobutyl carbamoyl methyl phosphine oxide) dissolved in 1-butyl-3-methylimidazolium bis(trifluoromethane sulfonyl)imide, a water immiscible ionic liquid. Slope analyses on the distribution data revealed the extraction of ML2 type species, where M = Np4+ or NpO2 2+, and L = CMPO. Studies were also carried out with Pu4+ and UO2 2+ under identical conditions. The nature of the extracted species was found to vary with the nature of the ionic species. 相似文献
5.
Dibakar Sarkar Dr. Ipsita Chakraborty Marcello Condorelli Baijayanti Ghosh Thorben Mass Dr. Markus Weingarth Dr. Atin K Mandal Prof. Carmelo La Rosa Dr. Vivekanandan Subramanian Dr. Anirban Bhunia 《ChemMedChem》2020,15(3):293-301
The three GxxxG repeating motifs from the C-terminal region of β-amyloid (Aβ) peptide play a significant role in regulating the aggregation kinetics of the peptide. Mutation of these glycine residues to leucine greatly accelerates the fibrillation process but generates a varied toxicity profile. Using an array of biophysical techniques, we demonstrated the uniqueness of the composite glycine residues in these structural repeats. We used solvent relaxation NMR spectroscopy to investigate the role played by the surrounding water molecules in determining the corresponding aggregation pathway. Notably, the conformational changes induced by Gly33 and Gly37 mutations result in significantly decreased toxicity in a neuronal cell line. Our results indicate that G33xxxG37 is the primary motif responsible for Aβ neurotoxicity, hence providing a direct structure–function correlation. Targeting this motif, therefore, can be a promising strategy to prevent neuronal cell death associated with Alzheimer's and other related diseases, such as type II diabetes and Parkinson's. 相似文献
6.
Iron-Based Nanoparticles for Toxic Organic Degradation: Silica Platform and Green Synthesis 总被引:1,自引:0,他引:1
Meeks ND Smuleac V Stevens C Bhattacharyya D 《Industrial & engineering chemistry research》2012,51(28):9581-9590
Iron and iron oxide nanoparticles (NPs) are finding wide applications for the remediation of various toxic chloro-organic compounds (such as trichloroethylene, TCE), via reductive and oxidative processes. In this study, Fe NPs (30-50 nm) are synthesized by reduction from ferric ions immobilized (by ion exchange) on a platform (two types of sulfonated silica particles), in order to prevent the NP agglomeration. Next, the Fe NPs are oxidized and their effectiveness for the oxidative dechlorination of TCE via the heterogeneous decomposition of hydrogen peroxide to OH? on the surface of the iron oxide NPs was demonstrated. For the reductive approach, the use of ascorbic acid as a "green" reducing agent in conjunction with a secondary metal (Pd) inhibits NP oxidation and agglomeration through surface adsorbed species. The Fe/Pd NPs have been successfully applied for the dechlorination of TCE (k(SA), surface-area normalized reaction rate, = 8.1 ×10(-4) L/m(2)h). 相似文献
7.
Optimal Dynamic Monitoring Network Design and Identification of Unknown Groundwater Pollution Sources 总被引:2,自引:2,他引:0
The identification of unknown pollution sources is a prerequisite for designing of a remediation strategy. In most of the
real world situations, it is difficult to identify the pollution sources without a scientifically designed efficient monitoring
network. The locations of the contaminant concentration measurement sites would determine the efficiency of the unknown source
identification process to a large extent. Therefore coupled and iterative sequential source identification and dynamic monitoring
network design framework is developed. The coupled approach provides a framework for necessary sequential exchange of information
between monitoring network and source identification methodology. The preliminary identification of unknown sources, based
on limited concentration data from existing arbitrarily located wells provides the initial rough estimate of the source fluxes.
These identified source fluxes are then utilized for designing an optimal monitoring network for the first stage. Both the
monitoring network and source identification process is repeated by sequential identification of sources and design of monitoring
network which provides the feedback information. In the optimal source identification model, the Jacobian matrix which is
the determinant for the search direction in the nonlinear optimization model links the groundwater flow-transport simulator
and the optimization method. For the optimal monitoring network design, the integer programming based optimal design model
requires as input, simulated sets of concentration data. In the proposed methodology, the concentration measurement data from
the designed and implemented monitoring network are used as feedback information for sequential identification of unknown
pollution sources. The potential applicability of the developed methodology is demonstrated for an illustrative study area. 相似文献
8.
Robert B. Grieves Jitendra K. Ghosal Dibakar Bhattacharyya 《Journal of the American Oil Chemists' Society》1968,45(9):591-593
Ion flotation studies have shown that a surface-active agent is useful for qualitative analysis of complex ions in dilute
aqueous solution, with the surfactant forming a particulate complex with the complex ion of concern. Experiments with a monovalent,
cationic surfactant have established the prevalence of Cr2O7
2− (HCrO4
−) and not CrO4
2−; of [Fe(CN)6]4− and [Fe(CN)5H2O]3−; and of [FeFe(CN)6]2− and not [FeFe(CN)6]− or [Fe(CN)6]3−. The results can be contrasted to those with ions that do not form particulate complexes with the surfactant, such as HPO4
2− and phenolate; with the latter, no qualitative analytical information can be gained. Ion flotation appears to be a promising
technique in general for the determination of ionic species present in aqueous solution; the surfactant must react with the
ion of significance to form a particulate complex and the initial surfactant concentration must be controlled carefully. 相似文献
9.
Wireless Networks - Though, Software Defined Networking (SDN) started with the wired networks, several architectural solutions have been proposed to incorporate SDN in the wireless domain, to... 相似文献
10.
David Schieche Mangena V. S. Murty Richard I. Kermode Dibakar Bhattacharyya 《Journal of chemical technology and biotechnology (Oxford, Oxfordshire : 1986)》1997,70(3):316-322
The biological hydrogenation of organic compounds using sulphate-reducing bacteria was investigated. A high pressure stainless steel bioreactor and an atmospheric pressure reactor were constructed so that identical reactions at different pressures could be compared. The mesophillic sulphate-reducing bacteria Desulfovibrio desulfuricans (ATCC 7757) were used. Qualitative tests showed that Desulfovibrio desulfuricans was able to retain its viability at hydrogen pressures up to 35 atmospheres at a temperature of 37°C when exposed to fumarate. Evidence of fumarate dismutation was observed since half of the fumarate was converted to succinate. The effect of bacterial cell concentration was also studied under hydrogen gas. For a doubling of the bacterial cell (reactivated) concentration, the conversion of fumarate doubled from 40% to 80% in 12 h. A first-order reaction rate model was fit to the fumarate concentration data. The first-order reaction rate constant was found to be a linear function of the bacterial cell concentration. ©1997 SCI 相似文献