A relatively simple, four-parameter extended hyperbolic model for interfaces was developed for use in soil-structure interaction analyses. The model accommodates arbitrary stress path directions and includes three important elements: (1) development of a yield surface during interface shear; (2) a formulation for yield-inducing shear stiffness that is applicable to any stress path orientation; and (3) a formulation for unloading-reloading shear stiffness. The model was evaluated against the results of shear tests performed at the interface between three different types of sand and a concrete surface under a variety of stress paths. Comparisons between measured and calculated interface response indicate that the model provides accurate estimates of the response of sand-to-concrete interfaces. 相似文献
Despite improvement in early diagnosis, surgical techniques, and general patient care, most deaths of cancer patients result from metastases. Recent studies have revealed that cytokines produced by cancer cells or by stromal cells play an important role into development the cancer metastasis. The formation of a cancer metastasis involves several major steps: 1) extensive vascularization; 2) local invasion; 3) adherence either to capillary endothelial cells or to subendothelial basement membrane; 4) extravasation; and 5) proliferation. In colon cancer, several cytokines such as growth factors, inflammatory cytokines, and angiogenic factors have been confirmed to be involved in each step of metastasis. This paper summarizes the involvement of cytokines in the development of invasion and metastasis in colon cancer. 相似文献
The use of computers in actual system applications is increasing with the availability of intelligent terminals on the shop floor. These terminals can be used by management as tools in the decision making process of planning shop floor operation. This paper discusses a pilot simulation study in the use of conventional Fortran-based simulation programs by shop floor management to:
1. 1. Participate in the evaluation of proposed FMS systems,
2. 2. Assess the impact of FMS acquisition on existing facilities,
3. 3. Assist in the identification of operational alternatives in “bottle neck” situations.
The pilot study employs a batch-oriented MRP system to provide daily updates of outstanding production center loadings on a monthly planning horizon. Two intelligent terminals are used to access a mini computer facility that executes the simulation models. The terminals have AT-compatible capabilities and are also used as data acquisition devices that support the numerically controlled operations within each work center.
The simulation models represent the 13 work centers of the firm and provide information about the average utilization of each work center, the number of parts in each queue and the average delay of parts in the queues. Future extensions of the models are planned to utilize the terminals' graphic animation capabilities to display the flow of production orders through the manufacturing facility. 相似文献
We report on high-resolution linewidth measurements of proton-implanted InGaAs-GaAs VCSELs employing the delayed self-heterodyne method. Devices with 16-/spl mu/m active diameter exhibit record low linewidths of 20 MHz and 4-MHz residual linewidth. The linewidth enhancement factor is accurately determined from the ratio of induced phase to amplitude modulation indexes. 相似文献
Corona discharge is applied to charge reduction electrospray mass spectrometry for the analysis of complex mixtures of biological molecules. Recent work has described a method of charge reduction (reducing the charge states of analyte ions generated by the electrospray process) employing the radioactive isotope 210Po to produce neutralizing species. A variation to this approach is presented, in which charge neutralization is mediated by ions produced in a corona discharge. Varying the corona discharge voltage controls the current and the degree of charge reduction, providing predominantly singly charged ions that are detected by a commercial electrospray time-of-flight mass spectrometer. This technique provides charge reduction for the simplification of ESI spectra, without need for any radioactive material. 相似文献
We demonstrate the possibility of generating intensity squeezed light with free-running or injected multimode vertical-cavity surface-emitting laser. Sub-shot-noise operation results from very strong anticorrelations between the transverse modes. The influence of the active media diameter on the amount of squeezing is analyzed 相似文献
Field-programmable gate arrays (FPGAs) are an important implementation medium for digital logic. Unfortunately, they currently suffer from poor silicon area utilization due to routing constraints. In this paper we present Triptych, an FPGA architecture designed to achieve improved logic density with competitive performance. This is done by allowing a per-mapping tradeoff between logic and routing resources, and with a routing scheme designed to match the structure of typical circuits. We show that, using manual placement, this architecture yields a logic density improvement of up to a factor of 3.5 over commercial FPGAs, with comparable performance. We also describe Montage, the first FPGA architecture to fully support asynchronous and synchronous interface circuits 相似文献
Field-programmable gate arrays (FPGAs) are becoming an increasingly important implementation medium for digital logic. One of the most important keys to using FPGAs effectively is a complete, automated software system for mapping onto the FPGA architecture. Unfortunately, many of the tools necessary require different techniques than traditional circuit implementation options, and these techniques are often developed specifically for only a single FPGA architecture. In this paper we describe automatic mapping tools for Triptych, an FPGA architecture with improved logic density and performance over commercial FPGAs. These tools include a simulated-annealing placement algorithm that handles the routability issues of fine-grained FPGAs, and an architecture-adaptive routing algorithm that can easily be retargeted to other FPGAs. We also describe extensions to these algorithms for mapping asynchronous circuits to Montage, the first FPGA architecture to completely support asynchronous and synchronous interface applications 相似文献