Surrogate models have been widely applied to correlate design variables and performance parameters in turbomachinery optimization applications. With more design variables and uncertain factors taken into account in an optimization design problem, the mathematical relations between the design variables and the performance parameters might present linear, low-order nonlinear or even high-order nonlinear characteristics, and are usually analytically unknown. Therefore, it is required that surrogate models have high adaptability and prediction accuracy for both the linear and nonlinear characteristics. The paper mainly investigates the effectiveness of an adaptive region segmentation combining surrogate model based on support vector regression and kriging model applied to a transonic axial compressor to approximate the complicated relationships between geometrical variables and objective performance outputs with different sampling methods and sizes. The purpose is to explore the prediction accuracy and computational efficiency of this adaptive surrogate model in real turbomachinery applications. Three different sampling techniques are studied: (1) uniform design; (2) Latin hypercube sampling method; (3) Sobol quasi-random design. For the low dimensional case with five variables, the adaptive region segmentation combining surrogate model performs better (not worse) than the single component surrogate in terms of prediction accuracy and computational efficiency. In the meanwhile, it is also noted that the uniform design applied to the adaptive surrogate model has more advantages over the Latin hypercube sampling method especially for the small sample size cases, both performing better than the Sobol quasi-random design. Moreover, a high dimensional case with 12 variables is also utilized to further validate the prediction advantage of the adaptive region segmentation combining surrogate model over the single component surrogate, and the computational results favor it. Overall, the adaptive region segmentation combining surrogate model has produced acceptable to high prediction accuracy in presenting complex relationships between the geometrical variables and the objective performance outputs and performed robustly for a transonic axial compressor problem.
We study an online scheduling problem with rejection, in which some rearrangement of the solution is allowed. This problem is called scheduling with rejection and withdrawal. Each arriving job has a processing time and a rejection cost associated with it, and it needs to be either assigned to a machine or rejected upon arrival. At termination, it is possible to choose at most a fixed number of scheduled jobs and withdraw them (i.e., decide to reject them). We study the minimization version, where the goal is to minimize the sum of the makespan and the total rejection cost (which corresponds to the penalty), and the maximization problem, where the goal is to maximize the sum of the minimum load and the total rejection cost (which corresponds to profit). We study environments of machines, which are the case of m identical machines and the case of two uniformly related machines, and show a strong relation between these problems and the related classic online scheduling problems which they generalize, in contrast to standard scheduling with rejection, which typically makes the scheduling problems harder. 相似文献
The MANDAS project has defined a layered architecture for the management of distributed applications. In this paper we examine a vertical slice of this architecture, namely the management applications and services related to configuration management. We introduce an information model which captures the configuration information for distributed applications and discuss a repository service based on the model. We define a set of services and management applications to support maintenance of configuration information, and describe how the different types of configuration information are collected. Finally, we present two management applications that use configuration information. 相似文献
Polyethylene terephthalate-exfoliated graphene nanocomposites were prepared by injection molding. Nanocomposites with graphene
platelets of 2, 5, 10, and 15% weight fractions were molded and tested for mechanical characterization. Transmission electron
microscopy imaging along with X-ray diffraction show that the graphene platelets remained intact and were dispersed into the
matrix. An exponential increase in the Young’s modulus of the nanocomposites was observed, but with current limits on exfoliation
they do not yet reach the potential suggested by idealized predictions. 相似文献
A convenient synthesis of imatinib, a potent inhibitor of ABL1 kinase and widely prescribed drug for the treatment of a variety of leukemias, was devised and applied to the construction of a series of novel imatinib analogues featuring a number of non‐aromatic structural motifs in place of the parent molecule's phenyl moiety. These analogues were subsequently evaluated for their biopharmaceutical properties (e.g., ABL1 kinase inhibitory activity, cytotoxicity). The bicyclo[1.1.1]pentane‐ and cubane‐containing analogues were found to possess higher themodynamic solubility, whereas cubane‐ and cyclohexyl‐containing analogues exhibited the highest inhibitory activity against ABL1 kinase and the most potent cytotoxicity values against cancer cell lines K562 and SUP‐B15. Molecular modeling was employed to rationalize the weak activity of the compounds against ABL1 kinase, and it is likely that the observed cytotoxicity of these agents arises through off‐target effects. 相似文献