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1.
Based on a qualitative study of the Stoner-Wohlfarth model, we point out that driving a magnetic tunnel junction (MTJ) with an alternative two-dimensional magnetic field allows to measure simultaneously two components of an external magnetic field. Only one single MTJ without a pinning layer is needed to measure both components of a magnetic field parallel to the junction plane. The response of the magnetometer does not depend on the resistance of the junction or the amplitude of its variations. A prototype has been manufactured and encouraging experimental results are presented. Sensitivities higher than 500 V/T and a noise level of 2 /spl mu/T//spl radic/Hz are reported.  相似文献   
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Targeted delivery of nanomedicine/nanoparticles (NM/NPs) to the site of disease (e.g., the tumor or lung injury) is of vital importance for improved therapeutic efficacy. Multimodal imaging platforms provide powerful tools for monitoring delivery and tissue distribution of drugs and NM/NPs. This study introduces a preclinical imaging platform combining X‐ray (two modes) and fluorescence imaging (three modes) techniques for time‐resolved in vivo and spatially resolved ex vivo visualization of mouse lungs during pulmonary NP delivery. Liquid mixtures of iodine (contrast agent for X‐ray) and/or (nano)particles (X‐ray absorbing and/or fluorescent) are delivered to different regions of the lung via intratracheal instillation, nasal aspiration, and ventilator‐assisted aerosol inhalation. It is demonstrated that in vivo propagation‐based phase‐contrast X‐ray imaging elucidates the dynamic process of pulmonary NP delivery, while ex vivo fluorescence imaging (e.g., tissue‐cleared light sheet fluorescence microscopy) reveals the quantitative 3D drug/particle distribution throughout the entire lung with cellular resolution. The novel and complementary information from this imaging platform unveils the dynamics and mechanisms of pulmonary NM/NP delivery and deposition for each of the delivery routes, which provides guidance on optimizing pulmonary delivery techniques and novel‐designed NM for targeting and efficacy.  相似文献   
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The quantum states of nano-objects can drive electrical transport properties across lateral and local-probe junctions. This raises the prospect, in a solid-state device, of electrically encoding information at the quantum level using spin-flip excitations between electron spins. However, this electronic state has no defined magnetic orientation and is short-lived. Using a novel vertical nanojunction process, these limitations are overcome and this steady-state capability is experimentally demonstrated in solid-state spintronic devices. The excited quantum state of a spin chain formed by Co phthalocyanine molecules coupled to a ferromagnetic electrode constitutes a distinct magnetic unit endowed with a coercive field. This generates a specific steady-state magnetoresistance trace that is tied to the spin-flip conductance channel, and is opposite in sign to the ground state magnetoresistance term, as expected from spin excitation transition rules. The experimental 5.9 meV thermal energy barrier between the ground and excited spin states is confirmed by density functional theory, in line with macrospin phenomenological modeling of magnetotransport results. This low-voltage control over a spin chain's quantum state and spintronic contribution lay a path for transmitting spin wave-encoded information across molecular layers in devices. It should also stimulate quantum prospects for the antiferromagnetic spintronics and oxides electronics communities.  相似文献   
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Materials science and device studies have, when implemented jointly as “operando” studies, better revealed the causal link between the properties of the device's materials and its operation, with applications ranging from gas sensing to information and energy technologies. Here, as a further step that maximizes this causal link, the paper focuses on the electronic properties of those atoms that drive a device's operation by using it to read out the materials property. It is demonstrated how this method can reveal insight into the operation of a macroscale, industrial‐grade microelectronic device on the atomic level. A magnetic tunnel junction's (MTJ's) current, which involves charge transport across different atomic species and interfaces, is measured while these atoms absorb soft X‐rays with synchrotron‐grade brilliance. X‐ray absorption is found to affect magnetotransport when the photon energy and linear polarization are tuned to excite Fe? O bonds parallel to the MTJ's interfaces. This explicit link between the device's spintronic performance and these Fe? O bonds, although predicted, challenges conventional wisdom on their detrimental spintronic impact. The technique opens interdisciplinary possibilities to directly probe the role of different atomic species on device operation, and shall considerably simplify the materials science iterations within device research.  相似文献   
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Frequently hailed for their dynamical capabilities, quadrotor vehicles are often employed as experimental platforms. However, questions surrounding achievable performance, influence of design parameters, and performance assessment of control strategies have remained largely unanswered. This paper presents an algorithm that allows the computation of quadrotor maneuvers that satisfy Pontryagin’s minimum principle with respect to time-optimality. Such maneuvers provide a useful lower bound on the duration of maneuvers, which can be used to assess performance of controllers and vehicle design parameters. Computations are based on a two-dimensional first-principles quadrotor model. The minimum principle is applied to this model to find that time-optimal trajectories are bang-bang in the thrust command, and bang-singular in the rotational rate control. This paper presents a procedure allowing the computation of time-optimal maneuvers for arbitrary initial and final states by solving the boundary value problem induced by the minimum principle. The usage of the computed maneuvers as a benchmark is demonstrated by evaluating quadrotor design parameters, and a linear feedback control law as an example of a control strategy. Computed maneuvers are verified experimentally by applying them to quadrocopters in the ETH Zurich Flying Machine Arena testbed.  相似文献   
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影响电动车使用增长率最大的因素是电池,而对电池整体性能有着关键性影响的便是电池传感器.本文将介绍电池传感器技术的进步对提升电动车电池性能的重要作用,对电流传感进行详细探讨,比较不同的传感技术以及各自的优缺点,同时介绍了AS8510的性能及在电动车中的应用.  相似文献   
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Current‐induced magnetization manipulation is a key issue for spintronic applications. This manipulation must be fast, deterministic, and nondestructive in order to function in device applications. Therefore, single‐ electronic‐pulse‐driven deterministic switching of the magnetization on the picosecond timescale represents a major step toward future developments of ultrafast spintronic systems. Here, the ultrafast magnetization dynamics in engineered Gdx [FeCo]1?x ‐based structures are studied to compare the effect of femtosecond laser and hot‐electron pulses. It is demonstrated that a single femtosecond hot‐electron pulse causes deterministic magnetization reversal in either Gd‐rich and FeCo‐rich alloys similarly to a femtosecond laser pulse. In addition, it is shown that the limiting factor of such manipulation for perpendicular magnetized films arises from the formation of a multidomain state due to dipolar interactions. By performing time‐resolved measurements under various magnetic fields, it is demonstrated that the same magnetization dynamics are observed for both light and hot‐electron excitation, and that the full magnetization reversal takes place within 40 ps. The efficiency of the ultrafast current‐induced magnetization manipulation is enhanced due to the ballistic transport of hot electrons before reaching the GdFeCo magnetic layer.  相似文献   
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In this study, endophytic bacteria belonging to the Bacillus genus were isolated from in vitro bulblets of Leucojum aestivum and their ability to produce Amaryllidaceae alkaloids was studied. Proton Nuclear Magnetic Resonance (1H NMR)-based metabolomics combined with multivariate data analysis was chosen to compare the metabolism of this plant (in vivo bulbs, in vitro bulblets) with those of the endophytic bacteria community. Primary metabolites were quantified by quantitative 1H NMR (qNMR) method. The results showed that tyrosine, one precursor of the Amaryllidaceae alkaloid biosynthesis pathway, was higher in endophytic extract compared to plant extract. In total, 22 compounds were identified including five molecules common to plant and endophyte extracts (tyrosine, isoleucine, valine, fatty acids and tyramine). In addition, endophytic extracts were analyzed using Liquid Chromatography-Mass Spectrometry (LC-MS) and Gas Chromatography-Mass Spectrometry (GC-MS) for the identification of compounds in very low concentrations. Five Amaryllidaceae alkaloids were detected in the extracts of endophytic bacteria. Lycorine, previously detected by 1H NMR, was confirmed with LC-MS analysis. Tazettine, pseudolycorine, acetylpseudolycorine, 1,2-dihydro-chlidanthine were also identified by LC-MS using the positive ionization mode or by GC-MS. In addition, 11 primary metabolites were identified in the endophytic extracts such as tyramine, which was obtained by decarboxylation of tyrosine. Thus, Bacillus sp. isolated from L. aestivum bulblets synthesized some primary and specialized metabolites in common with the L. aestivum plant. These endophytic bacteria are an interesting new approach for producing the Amaryllidaceae alkaloid such as lycorine.  相似文献   
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