A method for quantitative display of three-dimensional regional myocardial function

The DSR (dynamic spatial reconstructor), a multiple X-ray source scanner that generates stop action three-dimensional (3-D) images of a cylindrical volume, was used for quantitative imaging of left ventricular 3-D wall geometry and function in experimentally induced canine left ventricular myocardial infarction. Impaired regional myocardial function was induced by myocardial ischemia or infarction in four mongrel dogs by closed-chest occlusion of the proximal left anterior descending (LAD) coronary artery. At intervals of 6-14 weeks post occlusion, the dogs were scanned with the DSR during biatrial contrast injection. The 3-D shape, extent, and function of hypokinetic myocardium was measured from the DSR images utilizing measurement of the rate of local systolic wall thickening to detect regions of normal, ischemic, or scarred myocardium. The results were compared to scar size and anatomic distribution measured at postmortem examination. The anatomic extent and relationship of hypocontractile to normally contracting muscle was visualized by computer generated, pseudo 3-D shaded surface displays of the left ventricular chamber and by topographic projections of regional wall thickening rates onto a map of the left ventricular endocardial surface. The location of myocardial infarction and the surrounding zone of impaired function is clearly defined by this 3-D CT scanning procedure. The display method presented here provides both localization and quantification of the volume of ischemic and infarcted myocardium.     

Effects of Luminosity Contrast and Stimulus Duration on User Performance and Preference in a P300-Based Brain–Computer Interface

Brain–computer interfaces (BCI) have potential to provide a new channel of communication and control for people with severe motor disabilities. Although many empirical studies exist, few have specifically evaluated the impact of contributing factors on user performance and perception in BCI applications, especially for users with motor disabilities. This article reports the effects of luminosity contrast and stimulus duration on user performance and usage preference in a P300-based BCI application, P300 Speller. Ten participants with neuromuscular disabilities (amyotrophic lateral sclerosis and cerebral palsy) and 10 able-bodied participants were asked to spell six 10-character phrases in the P300 Speller. The overall accuracy was 76.5% for the able-bodied participants and 26.8% for participants with motor disabilities. The results showed that luminosity contrast and stimulus duration have significant effects on user performance. In addition, participants preferred high luminosity contrast with middle or short stimulus duration. However, these effects on user performance and preference varied for participants with and without motor disabilities. The results also indicated that although most participants with motor disabilities can establish BCI control, BCI illiteracy does exist. These results of the study should provide insights into the future research of the BCI systems, especially the real-world applicability of the BCI applications as a nonmuscular communication and control system for people with severe motor disabilities.     

Incorporating affective customer needs for luxuriousness into product design attributes

In a highly competitive market, customers' product affection is a critical factor to product success. However, understanding customers' affective needs is difficult to grasp; product design practitioners often misunderstand what customers really want. In this study we report our experience in developing and using an affective design framework that identified critical affective features customers have on products and are systematically incorporated into product design attributes. To identify key affective features such as luxuriousness, we utilized the Kansei engineering methodology. This approach consists of three steps: (1) selecting related affective features and product design attributes through a comprehensive literature survey, expert panel opinion, and focus group interviews; (2) conducting evaluation experiments; and (3) developing Kansei models using multivariate statistical analysis and analyzing critical product design attributes. To demonstrate applicability of the proposed affective design framework, 30 customers and 30 product design practitioners participated in an evaluation experiment for car crash pads, and 44 customers and 20 designers participated in an evaluation experiment for two interior room products (wallpapers and flooring materials). The evaluation experiments were conducted via systematically developed questionnaires consisting of a 7‐point semantic differential scale and a 100‐point magnitude estimation scale. The results of the experiments were analyzed using principal component regression and quantification theory type I method. Using the analyzed survey data, the relationship between luxuriousness and related affective features and product design attributes were identified. This relationship indicated that there was a significant difference in the perception of luxuriousness between customers and designers. Consequently, it is expected that the results of this study could provide a foundation for developing affective products. © 2009 Wiley Periodicals, Inc.     

Severe motor disability affects functional cortical integration in the context of brain-computer interface (BCI) use

The purpose of this study was to investigate cortical interaction between brain regions in people with and without severe motor disability during brain-computer interface (BCI) operation through coherence analysis. Eighteen subjects, including six patients with cerebral palsy (CP) and three patients with amyotrophic lateral sclerosis (ALS), participated. The results showed (1) the existence of BCI performance difference caused by severe motor disability; (2) different coherence patterns between participants with and without severe motor disability during BCI operation and (3) effects of motor disability on cortical connections varying in the brain regions for the different frequency bands, indicating reduced cortical differentiation and specialisation. Participants with severe neuromuscular impairments, as compared with the able-bodied group, recruited more cortical regions to compensate for the difficulties caused by their motor disability, reflecting a less efficient operating strategy for the BCI task. This study demonstrated that coherence analysis can be applied to examine the ways cortical networks cooperate with each other during BCI tasks. PRACTITIONER SUMMARY: Few studies have investigated the electrophysiological underpinnings of differences in BCI performance. This study contributes by assessing neuronal synchrony among brain regions. Our findings revealed that severe motor disability causes more cortical areas to be recruited to perform the BCI task, indicating reduced cortical differentiation and specialisation.     

Investigations concerning multi-component current contact tips for automatic MIG/MAG welding

Abstract

A report is given in this document on investigations concerning the development of multi-component current contact tips for MIG/MAG robot welding torches. Bi-metal pressure units were fitted in the guide channels to improve the current transmission.     

Discrete derivative method for adaptive notch filter-based frequency estimators

International Journal of Control, Automation and Systems - This paper presents a new discrete derivative method for adaptive notch filter (ANF)-based frequency estimators. ANF-based frequency...     

Clicks and Mortar: Balancing Brick and Mortar Business Strategy and Operations with Auxiliary Electronic Commerce

Balancing business strategy and operations between electronic commerce and brick and mortar channels (clicks and mortar) is an ongoing challenge for many businesses. A group of traditional brick and mortar firms were examined in order to understand how they balance strategy and operations between electronic commerce and traditional (brick and mortar) business channels. Results of the study indicated several distinct approaches to achieving this balance. Most of these approaches belie the idea that it is uniformly beneficial to deploy electronic commerce to mirror all of a firm's primary value chain activities. Instead, the study indicated that firm involvement with electronic commerce is often best minimized for the sake of successful business strategy and operations. Despite the necessarily limited and auxiliary role of electronic commerce for traditional firms, it still can help in supporting these firms' business to consumer operations in some surprising ways.     

A stochastic control model for optimal timing of climate policies

A stochastic control model is proposed as a paradigm for the design of optimal timing of greenhouse gas (GHG) emission abatement. The resolution of uncertainty concerning climate sensitivity and the technological breakthrough providing access to a carbon-free production economy are modeled as controlled stochastic jump processes. The optimal policy is characterized using the dynamic programming solution to a piecewise deterministic optimal control problem. A numerical illustration is developed with a set of parameters calibrated on recently proposed models for integrated assessment of climate policies. The results are interpreted and the insights they provide on the timing issue of climate policy are discussed.