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Investigated the relationships among magazine exposure, self-objectification, body shape dissatisfaction, and eating disorder symptomatology in 150 men and women (aged 18-42 yrs). Women reading beauty magazines and men reading fitness magazines internalized societal ideals (internalization). For women, beauty magazines predicted self-objectification, mediated by internalization. For men, only internalization predicted self-objectification. For men, fitness magazines predicted body shape dissatisfaction, mediated by internalization. For women, only internalization predicted body shape dissatisfaction. Reading magazines also predicted eating problems for men and women, for women this was mediated by internalization. Findings suggest that magazine reading is related to concerns with physical appearance and eating behaviors. Many of the relationships previously found for women are similar for men. A sociocultural model is used to explain these results. (PsycINFO Database Record (c) 2010 APA, all rights reserved)  相似文献   
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Based on interdependence theory and the interpersonal process model of intimacy, individuals' personal attributes, perceptions, cognitions, and affect should influence relationship expectations. Self-disclosure is one form of behavioural interdependence and includes perceptions of the partner's disclosure. These behaviours (own disclosure) and perceptions (perceived partner's disclosure) should impact cognitions about the self and partner (cognitive closeness) and affect about the relationship (satisfaction). Personal attributes also determine how people react. Allocentrism, one personal attribute, refers to an individual's orientation involving emotional ties and dependence on others. A study involving cross-sex friendships tested whether allocentrism predicted own disclosure, own disclosure predicted perceived friend's disclosure, which predicted closeness, and finally closeness predicted satisfaction. A series of hierarchical regressions supported these relations and accounted for 23% of the variance in satisfaction. (PsycINFO Database Record (c) 2010 APA, all rights reserved)  相似文献   
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In vivo delivery of siRNAs designed to inhibit genes important in cancer and other diseases continues to be an important biomedical goal. A new nanoparticle construct that is engineered for efficient delivery of siRNA to tumors is now described. The construct comprises a 47‐nm mesoporous silica nanoparticle core coated with a crosslinked polyethyleneimine–polyethyleneglycol copolymer, carrying siRNA against the human epidermal growth factor receptor type 2 (HER2) oncogene, and coupled to the anti‐HER2 monoclonal antibody (trastuzumab). The construct is engineered to increase siRNA blood half‐life, enhance tumor‐specific cellular uptake, and maximize siRNA knockdown efficacy. The optimized anti‐HER2 nanoparticles produce apoptotic death in HER2 positive (HER2+) breast cancer cells grown in vitro, but not in HER2 negative (HER2?) cells. One dose of the siHER2–nanoparticles reduces HER2 protein levels by 60% in trastuzumab‐resistant HCC1954 xenografts. Administration of multiple intravenous doses over 3 weeks significantly inhibits tumor growth (p < 0.004). The siHER2‐nanoparticles have an excellent safety profile in terms of blood compatibility and low cytokine induction, when exposed to human peripheral blood mononuclear cells. The construct can be produced with high batch‐to‐batch reproducibility and the production methods are suitable for large‐scale production. These results suggest that this siHER2‐nanoparticle is ready for clinical evaluation.  相似文献   
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研究了两种组织形貌相似的核燃料包壳管材M5和N36锆合金的拉伸性能和爆破性能.利用X射线衍射仪分析了它们的织构.试验结果表明,两种材料表现出明显的各向异性.同时分析了织构因素对Schmiidt因子的影响,结合研究管材的力学性能各向异性,建立了拉伸、爆破屈服强度同织构的定性关系.  相似文献   
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研究了两种组织形貌相似的核燃料包壳管材M5和N36锆合金的拉伸性能和爆破性能.利用X射线衍射仪分析了它们的织构.试验结果表明,两种材料表现出明显的各向异性.同时分析了织构因素对Schmiidt因子的影响,结合研究管材的力学性能各向异性,建立了拉伸、爆破屈服强度同织构的定性关系.  相似文献   
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46 male and 108 female students' (aged 18–33 yrs) attitudes regarding the acceptance and expectation of sexual assault were examined. Participants also completed M. Burt's (1980) Rape Myth Acceptance (RMA) Scale. It is noted that acceptance of sexual aggression can lead to the exoneration of the perpetrator, whereas expectations of sexual aggression can lead to victim blaming. A feminist perspective of rape, with a focus on sexual socialization, indicates that rape myth beliefs deny or justify male sexual aggression against women. Therefore, it was predicted and found that high RMA participants expected and accepted more sexual assault than low RMA participants. Sexual assault was also expected more often than it was accepted, suggesting that these judgments are made separately. (PsycINFO Database Record (c) 2010 APA, all rights reserved)  相似文献   
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Research has examined the relation of prior contact and/or symbolic beliefs on attitudes toward homosexuals or gay men. Little research though has been conducted on attitudes toward lesbian women. We examined the simultaneous relationships of symbolic beliefs and prior contact on attitudes toward gay men and attitudes toward lesbian women. Regression analyses indicated that on their own either symbolic beliefs or prior contact were significant predictors of attitudes towards both groups. When examined together though symbolic beliefs predicted attitudes toward lesbian women whereas prior contact predicted attitudes toward gay men. Overall, participants had more contact with gay men than lesbian women. The implications of our results are discussed in terms of the contact hypothesis. (PsycINFO Database Record (c) 2010 APA, all rights reserved)  相似文献   
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织构对锆合金内压蠕变性能的影响   总被引:1,自引:0,他引:1  
研究了两种组织形貌相似的锆合金M5TM和N36锆合金核燃料包壳管材的内压蠕变性能,利用X射线衍射仪分析了它们的织构,根据试验数据分析了试验应力水平对蠕变机理的影响,提出用合金在试验条件下的屈服应力作为规一化值建立蠕变速率-规一化应力关系曲线,该法更能够体现合金织构对内压蠕变行为的影响,尤其是蠕变幂函数规律失效的临界转变应力水平.  相似文献   
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