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User information and communication resources - such as precise location information and direction, altitude, light, and humidity measurements (via sensors) - are becoming more available in end devices. This increasing range of information can enable context-aware informational services as well as linking digital objects to physical objects a user is observing. Thus, mobile users can obtain relevant information about real-world objects while simultaneously staying in touch with other users. The author describes an open, scalable service architecture in which context-aware service negotiation lets entities establish communication and negotiate services without a third party's assistance and without advance knowledge of either party's features. Context information can help hide data complexity from users until they need to make choices regarding such things as payments or object interactions.  相似文献   
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This article analyzes the challenges of supporting continual changes of context information in Internet-of-Things applications. These applications require a constant flow of continuously changing information from sensor based sources in order to ensure a high quality-of-experience. However, an uncontrolled flow between sources and sinks on a global scale wastes resources, such as computational power, communication bandwidth, and battery time. In response to these challenges we present a general approach which focuses on four layers where we provide a proposed solution to each layer. We have realized the general model into a proof-of-concept implementation running on devices with limited resources, where we can moderate the information exchange based on relevance and sought after quality-of-experience by the applications. In conclusion, we evaluate our solution and present a summary of our experiences regarding the impact of continuously changing information on the Internet-of-Things.  相似文献   
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To improve cognitive and behavioral therapies (CBT) for depression, several approaches recommend an increased focus on the occurrence of problems as they occur in the therapeutic relationship or in relation to the live therapy process, referred to as present-focused. A lingering question has been the degree to which CBT therapists already engage in present-focused work. This study utilized sessions from recent trials of CBT for depression and, in Phase I, raters identified present-focused interventions on a turn-by-turn basis. Phase II raters used a qualitative analysis to determine categories of present-focused interventions. Results indicated that therapists rarely focused on the therapeutic relationship; when they did, it was often transient and lacking in the elaborations suggested by newer approaches. Therapists more often performed therapy process and emotion focused interventions, but these also tended to lack elaboration. (PsycINFO Database Record (c) 2010 APA, all rights reserved)  相似文献   
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The aims of the study were to investigate the effects of immunization against GnRH using OL protein (Ovalbumin-LHRH-7) on feedlot performance, carcass, meat quality and some reproductive traits in K?v?rc?k ram lambs. Ram lambs in the immunization (I, n = 7) group were immunized against GnRH using OL protein and boosted 2 weeks later. Control (C, n = 7) group was not treated. The animals were kept at pasture for 6 weeks after the first immunization, subjected to a 70 day fattening program, and then slaughtered. Growth performance, various carcass and meat quality characteristics were not affected from the immunization. GnRH immunization induced GnRH antibody production, suppressed testosterone production and testicular growth (P < 0.01). Testicular structure was negatively affected from the immunization, but not pituitary. These results suggest that immunization against GnRH with OL could be an alternative castration technique in ram lambs without negatively affecting carcass and meat quality characteristics.  相似文献   
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Presents a clinical model of the development of self. The model focuses on the early learning responsible for linguistic self-referents such as "I" and "me." This model offers an account for why some patients, such as those with borderline personality disorder (BPD), feel that they "do not know who they are" or that their sense of self is controlled by other people, while other patients have a sense of a secure, stable self that is not prey to the whims of others. The authors administered the Experiencing of Self Scale, which measures the degree to which other people influence the experience of self, along with the Self-Esteem Scale and the Dissociative Experiences Scale to 284 undergraduate students (mean age 19.2 yrs) and 14 BPD patients (mean age 41.1 yrs). Results show that the degree to which other people influence the experience of self depended on the nature and closeness of the people involved, that those in the BPD sample suffered from excessive influence of other people over the experience of self relative to the undergraduates, and that the degree of influence correlated predictably with high dissociation and low self-esteem. Implications for conceptualizing BPD and narcissistic personality disorder are discussed, and clinical applications are suggested. (PsycINFO Database Record (c) 2010 APA, all rights reserved)  相似文献   
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This article introduces a novel, open, and scalable service architecture for context-aware personal communication. In contrast to the network-centric open service access in third-generation mobile networks, this architecture moves the point of integration for user services out to the mobile devices, where we can create support for context-aware computing and communication. Support for peer-to-peer service negotiation with minimal a priori shared knowledge, context representation, and reasoning about context enables the mobile agents (that represent users and other entities) to be aware of and react to any event and thus context. Hence, the delivery of context-aware applications to users intertwining digital and physical objects in mobile interactive spaces leverages events from sensors, mobility support, and digital entities. Finally, a presentation of our prototype and experiences from the HotTown project demonstrates the feasibility of the approach and provides some examples of the enabled user communication for large-scale mobile networks.  相似文献   
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Porphyromonas gingivalis, a periodontal pathogen can invade primary cultures of gingival epithelial cells. This invasion was significantly inhibited (74-81%) by thapsigargin and 1,2-bis(2-aminophenoxy)ethane-N,N,N1,N1-tetraacetic acid, acetoxymethyl ester (BAPTA/AM), but not by EDTA or amiloride. Release of Ca2+ from an intracellular store and the subsequent increase in cytosolic [Ca2+] may, therefore, be involved in the invasion process, while Ca2+ influx is not. Moreover, cytosolic [Ca2+] was found to increase transiently in about 30% of gingival epithelial cells acutely exposed to P. gingivalis, but not in unexposed cells, or in cells exposed to noninvasive Escherichia coli. These findings indicate that P. gingivalis invasion of epithelial cells is correlated with activation of [Ca2+]-dependent host cell signaling systems.  相似文献   
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