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1.
A pruning algorithm of P.A. Chou et al. (1989) for designing optimal tree structures identifies only those codebooks which lie on the convex hull of the original codebook's operational distortion rate function. The authors introduce a modified version of the original algorithm, which identifies a large number of codebooks having minimum average distortion, under the constraint that, in each step, only modes having no descendents are removed from the tree. All codebooks generated by the original algorithm are also generated by this algorithm. The new algorithm generates a much larger number of codebooks in the middle- and low-rate regions. The additional codebooks permit operation near the codebook's operational distortion rate function without time sharing by choosing from the increased number of available bit rates. Despite the statistical mismatch which occurs when coding data outside the training sequence, these pruned codebooks retain their performance advantage over full search vector quantizers (VQs) for a large range of rates.  相似文献   
2.
BACKGROUND: FRTL-5 thyroid cells are a cell line extensively used for the investigation of thyroid functions. Activation of alpha-1 adrenergic receptors stimulates both arachidonic acid (AA) release and cytosolic Ca2+ increase in this cell line. Cytosolic Ca2+ and arachidonic acid are known to be important second messengers regulating a variety of thyroid functions. The generation of these messengers is regulated primarily by two different types of phospholipases, phospholipase C (PLC) and phospholipase A2 (PLA2). METHODS: Norepinephrine (NE, 10 mumol/L) was used as an alpha-1 adrenergic activator, and cytosolic-free Ca2+ concentration ([Ca2+]i) was determined using the fluorescent dye indo-1. Arachidonic acid release was measured as an indicator of PLA2 activation, and protein kinase C (PKC) activity determination and isoforms identification were performed using commercial kits. RESULTS: Norepinephrine increased [Ca2+]i and AA release. Prevention of NE-induced cytosolic Ca2+ influx, either by removal of extracellular Ca2+ or by use of Ca2+ channel blockers, NiCl2 or CoCl2, inhibited AA generation entirely. Inhibition of NE-induced increase in [Ca2+]i by the Ca2+ chelator, 1,2-bis(2-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid (BAPTA), also significantly suppressed NE-induced AA release. Inhibition of PKC activity by PKC inhibitors (H-7 or staurosporine) or downregulation induced by prolonged treatment with phorbol 12-myristate 13-acetate (PMA) or thyleametoxin (TX) significantly blocked the NE-induced AA release, which indicates PKC is involved in mediating NE-induced AA release. Protein kinase C activity measurement indicated that NE induced an activation of PKC in 5 minutes. To further characterize the role of PKC or Ca2+ in regulation of AA release, we identified PKC isoforms by immunoblotting with specific antibodies against 8 different Protein kinase C isoforms. PKC-alpha, -beta I, -beta II, -gamma, delta, -epsilon, -zeta, and -eta isoforms were identified. Norepinephrine induced translocation of PKC-alpha, -beta I, -beta II, -gamma, -delta, and -epsilon isoforms but not -zeta and -eta from cytosol to membrane. Chelation of intracellular Ca2+, prevention of Ca2+ influx, or prolonged treatment with thymeleatoxin (TX) completely blocked the NE-induced translocation of PKC-alpha. CONCLUSIONS: These results, taken together with data obtained from AA experiments, suggest that PKC plays a critical role in alpha-1 adrenergic receptor mediated PLA2 activation and subsequent AA release. Extracellular Ca2+ influx is a prerequisite for both PKC-alpha translocation and AA release. Whether Ca2+ acts directly upon the PLA2, or via PKC-alpha, to regulate AA generation is an intriguing question that remains to be clarified.  相似文献   
3.
The widening of interest and scope of property management and maintenance has attracted a greater diversity of professional disciplines into facilities management. Dr Quah, coordinator of CIB W70 on Management, Maintenance and Modernization of Building facilities, expresses her personal views on the current fascination with the subject.  相似文献   
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根据三点弯曲缺口梁的荷载与裂缝张开位移曲线,用反分析法确定了钢纤维水泥砂浆的拉伸残余强度。试验制作了5种不同体积含量的钢纤维水泥砂浆试件。采用虚拟裂缝模型用有限元法数值模拟了三点弯曲缺口梁的荷载与裂缝张开位移,用反分析法确定了钢纤维水泥砂浆的弹性模量和拉伸残余强度。研究结果表明,数值模拟得到的钢纤维水泥砂浆弹性模量以及三点弯曲缺口梁荷载与裂缝张开位移曲线均与试验结果吻合较好,且在常用的钢纤维含量范围内,钢纤维水泥砂浆的残余强度与钢纤维含量基本上成正比。  相似文献   
6.
A novel magnetically actuated 8/spl times/8-port MEMS-based fiber-optic switch is described. Fiber-to-fiber insertion loss measurements of six 8/spl times/8 switch units show average and worst-case insertion loss of 1.3 dB and 2 dB, respectively. Low insertion loss is achieved through a unique MEMS design that uses anisotropically etched single-crystal silicon sidewalls to provide a global mechanical alignment stop for an array of MEMS mirrors. This alignment surface produces a uniform and repeatable mirror angle across the mirror array. Mirror misalignment is attributed to the surface roughness of the silicon sidewalls. Repeated interferometric measurements of the mirrors of 24 8/spl times/8 switch units show repeatability of the mirror angle of 3/spl times/10/sup -3/ degrees, while the uniformity of the mirror angle across the MEMS array is 2/spl times/10/sup -2/ degrees, in agreement with the angular error predicted from measurements of sidewall surface roughness. In turn, the average repeatability and uniformity of the insertion loss are 0.01 dB and 1 dB, respectively, in agreement with predictions based on the interferometric measurements. Finally, the unique dynamics of the magnetic actuation and electrostatic addressing scheme are described. Measurements show that fast switching can be achieved by driving the mirrors with a magnetic pulse that is faster than the mechanical resonant frequency of the mirror, relying on an electrostatic clamping force to capture the mirror as it overshoots the magnetic field angle. This actuation scheme is shown to result in switching times of 8.5 ms to 13.5 ms, but requires accurate control of the kinetic energy of the mirror.  相似文献   
7.
Huang H  Lim CK  Tse MS  Guo J  Tan OK 《Nanoscale》2012,4(5):1491-1496
SnO(2) nanorod arrays have been deposited on 4 inch SiO(2)/Si and Si wafers and stainless steel substrates by plasma-enhanced chemical vapor deposition without any high temperature treatment or additional catalysis. The SnO(2) nanorods grow up from seed nanocrystals along the [110] preferential direction by a self-catalyzed vapor-solid growth mechanism. The surface of the SnO(2) nanorods was modified by ZnO, Pt and Ni nanocrystals. After surface modification, the field emission properties of the SnO(2) nanorod arrays are improved. The Ni nanocrystal with sharp tips and edges act as additional field emission sites to SnO(2) nanorods and thus the Ni/SnO(2)/SiO(2)/Si outperforms other samples due to the synergistic effects of good conductivity and hierarchical sharp apexes. The field enhancement factor of the Ni/SnO(2)/SiO(2)/Si increased around 3 times while the turn-on field of 8.0 V μm(-1) is about one third of the SnO(2)/SiO(2)/Si device.  相似文献   
8.
A 1D flame model was developed to analyze the heat transport occurring in the cylindrical micro combustors. The one-step global reaction mechanisms were employed for three fuel–air mixtures (H2–air, CH4–air and C3H8–air) to account for the difference of fuel property in terms of the kinetics. The effects of various parameters such as the combustor size, fuel property, fuel–air equivalence ratio and unburned mixture temperature on the heat loss ratio (defined as Ql/Qin) and the heat recirculation ratio (defined as Qrecir/Ql) were investigated. The results indicated that these parameters have significant effects on the two ratios, and therefore should be carefully managed in order to achieve efficient and stable combustion. After comparing the results of different fuel–air mixtures, it is concluded that hydrogen is superior to methane and propane as the fuel for micro combustion engines owing to its higher flame temperature and thinner flame thickness, which favors the reduction of heat loss from the flame zone.  相似文献   
9.
The inverse scattering for two-dimensional conductors is investigated. Assume that an incident wave is incident upon conducting cylinders of unknown shape and the scattered field is measured outside. By properly processing the scattering data, the position and shape of the conducting scatterers can then be reconstructed. The proposed theory of inverse scattering is a combination of the diffraction tomography and the equivalent source method. To overcome the ill-posedness, the condition of the measured scattered field and the boundary condition on the conductor surfaces are combined and recast into an optimization problem using the least-squares concept. By comparing the reconstructed and the prescribed results, the inversion algorithms are numerically examined. Note that if a priori information of the shape is sufficient and the equivalent sources are properly placed, the algorithms can be flexibly applied to the cases of multiple conductors. Also the effects of noise contamination and multiple scattering on the reconstruction result are numerically investigated  相似文献   
10.
A noble type of oxygen-sensitive and electrical-conductive material, ZrO/sub 2/-based with /spl alpha/-Fe/sub 2/O/sub 3/ thick-film gas sensor, was investigated for low operating temperature. Amorphous-like solid solutions of x/spl alpha/-Fe/sub 2/O/sub 3/-(1-x)ZrO/sub 2/ powders were derived using the high-energy ball milling technique, and their physical and microstructural properties were characterized from DTA, XRD, TEM, and XPS. The oxygen gas-sensing properties of the screen-printed thick-film gas sensors fabricated from such mechanically-alloyed materials were characterized systematically. Very good sensing properties were obtained with a relative resistance value of 82 in 20% oxygen, and at a low operating temperature of 320/spl deg/C. AC impedance spectra and thermally stimulated current were characterized to investigate the conduction properties of the solid solution, 0.2/spl alpha/-Fe/sub 2/O/sub 3/-0.8ZrO/sub 2/, in air and nitrogen (carrier gas), respectively. It was found that the Arrhenius plots of /spl sigma/T versus 1000/T have two distinct gradients corresponding to two activation energies in the high and low temperature regions. The transition temperature occurs at about 320/spl deg/C that corresponds to an optimal operating temperature of the gas sensor. It is believed that the high oxygen vacancy concentration present in the solid solution, 0.2/spl alpha/-Fe/sub 2/O/sub 3/-0.8ZrO/sub 2/, and the dissociation of the associated oxygen vacancy defect complexes at 320/spl deg/C are the critical factors for the high relative resistance to oxygen gas at low operating temperature.  相似文献   
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