Lateral habits ofn-alkane single crystals

The lateral crystal habits ofn-alkanes (n-C _n H_2n+2) have been observed just below the melting points by optical microscopy forn=18, 19, 20, 22, 24, 34, 44, 50 and 65. The shape of the crystals depends on the crystal phase: circular in the rotator phase, lenticular in phase C, and diamond in the low-temperature phase. The rounding of the lateral shape can be explained in terms of thermal roughening of the lateral faces in the disordered phases at high temperature.     

Chemical Modification of Phage-Displayed Helix-Loop-Helix Peptides to Construct Kinase-Focused Libraries

Conformationally constrained peptides hold promise as molecular tools in chemical biology and as a new modality in drug discovery. The construction and screening of a target-focused library could be a promising approach for the generation of de novo ligands or inhibitors against target proteins. Here, we have prepared a protein kinase-focused library by chemically modifying helix-loop-helix (HLH) peptides displayed on phage and subsequently tethered to adenosine. The library was screened against aurora kinase A (AurA). The selected HLH peptide Bip - 3 retained the α-helical structure and bound to AurA with a K_D value of 13.7 μM. Bip - 3 and the adenosine-tethered peptide Bip - 3 - Adc provided IC₅₀ values of 103 μM and 7.7 μM, respectively, suggesting that Bip - 3 - Adc bivalently inhibited AurA. In addition, the selectivity of Bip - 3 - Adc to several protein kinases was tested, and was highest against AurA. These results demonstrate that chemical modification can enable the construction of a kinase-focused library of phage-displayed HLH peptides.     

A preliminary study on learning effect in a contact positioning task in a virtual environment

How the human central nervous system adjusts sensorimotor coordination to haptic stimuli is a major topic in several fields including robotics. There are studies focusing on contact positioning tasks such as catching a ball or a volley in tennis, where position control of a human hand is required only at the moment of contact for successful completion of the tasks. A previous study dealt with a task of catching a ball in a virtual environment, and reported an interesting observation of the learning process in the relationship between operational performance and energy consumption of an operator; however, the operational condition given to the operators in the previous study seemed to be relatively simple. The interest in this paper is similar to that of the previous study; however, this paper considers application of a slightly more complex operational condition to a task of catching a ball. For corresponding to increase of difficulty in operation in the task, two movements of a paddle for catching a ball are given to operators, and difference between the movements is observed. Although the final goal of the study in this paper is similar to that in the previous study, this paper considers how learning effect can be observed in operational performance by comparing the performance of novice operators with that of experienced operators. The comparison shows differences in the performances between the operators from three analytic aspects. This paper also considers how many operations are required for novice operators to exhibit the learning effect in operational performance.     

A Quasi-ARMAX approach to modelling of non-linear systems

This paper proposes a class of quasi-ARMAX models for non-linear systems. Similar to ordinary non-linear ARMAX models, the quasi-ARMAX models are flexible black-box models, but they have various linearity properties similar to those of linear ARMAX models. A modelling scheme is introduced to construct models consisting of two parts: a macro-part and a kernel-part. By using Taylor expansion and other mathematical transformation techniques, it is first constructed as a class of quasi-ARMAX interfaces (macro-parts) that have various linearity properties but contain some complicated coefficients. MIMO neurofuzzy models (kernel-parts) are then introduced to represent the complicated coefficients. It is shown that the proposed quasi-ARMAX models have both good approximation ability and some easy-to-use properties. The proposed models have been successfully applied to prediction, fault detection and adaptive control of non-linear systems.     

Phytochemical Constituents,Attenuated Total Reflectance Fourier Transform Infrared Analysis and Antimicrobial Activity of Four Plant Leaves Used for Preparing Rice Beer in Assam,India

Phytochemicals content and antimicrobial activity of Artocarpus heterophyllus, Cyclosorus extensa, Oldendia corymbosa, and Alpinia malaccensis were investigated. Maximum alkaloids and terpenoids were found in A. heterophyllus; tannins and saponins in C. extensa; flavonoids, polyphenols, and phytosterols in O. corymbosa and anthraquinone, glycosides, and anthocyaninin A. malaccensis. Aqueous, methanolic, ethyl acetate, and hexane extracts were prepared from all the leaves. Attenuated total reflectance Fourier transform infrared spectrophotometric (ATR-FTIR) analysis revealed that alkanes and alkyl halides were prevalent in all the extracts and the ethyl acetate extracts contained comparatively higher number of functional groups, which were also more effective against Candida albicans, Escherichia coli, and Staphylococcus aureus. The minimum inhibitory concentration values of A. malaccensis against the tested pathogens were found to be lesser than the other species.     

Selectivity and mechanism for skeletal isomerization of alkanes over typical solid acids and their Pt-promoted catalysts

Selectivities for skeletal isomerizations of n-butane and n-pentane catalyzed by typical solid acids such as Cs_2.5H_0.5PW₁₂O₄₀ (Cs2.5), SO₄²⁻/ZrO₂, WO₃/ZrO₂, and H-ZSM-5 and their Pt-promoted catalysts were compared. High selectivities for n-butane and low selectivity for n-pentane were observed over Cs2.5 and SO₄²⁻/ZrO₂, while H-ZSM-5 was much less selective, and WO₃/ZrO₂ was highly selective for both reactions. The Pt-promoted solid acids were usually selective for these reactions in the presence of H₂ except for Pt-H-ZSM-5 for n-butane isomerization. Both the acid strength and pore structure would be factors influencing the selectivity. Mechanism of skeletal isomerization of n-butane was investigated by using 1,4-¹³C₂-n-butane over Cs2.5 and Pt–Cs2.5. It was concluded that n-butane isomerization proceeded mainly via monomolecular pathway with intramolecular rearrangement on Pt–Cs2.5, while it occurred through bimolecular pathway with intermolecular rearrangement on Cs2.5. The higher selectivity on Pt–Cs2.5 would be brought about by the monomolecular mechanism. In the skeletal isomerization of cyclohexane, Pt–Cs2.5/SiO₂ was highly active and selective, while Pt–Cs2.5 was less selective. Control in the acid strength of Cs2.5 by the supporting would be responsible for the high selectivity.     

Liquid‐phase sintering of highly Na+ ion conducting Na3Zr2Si2PO12 ceramics using Na3BO3 additive

Na₃Zr₂Si₂PO₁₂ (NASICON) is a promising material as a solid electrolyte for all‐solid‐state sodium batteries. Nevertheless, one challenge for the application of NASICON in batteries is their high sintering temperature above 1200°C, which can lead to volatilization of light elements and undesirable side reactions with electrode materials at such high temperatures. In this study, liquid‐phase sintering of NASICON with a Na₃BO₃ (NBO) additive was performed for the first time to lower the NASICON sintering temperature. A dense NASICON‐based ceramic was successfully obtained by sintering at 900°C with 4.8 wt% NBO. This liquid‐phase sintered NASICON ceramic exhibited high total conductivity of ~1 × 10^?3 S cm^?1 at room temperature and low conduction activation energy of 28 kJ mol^?1. Since the room‐temperature conductivity is identical to that of conventional high‐temperature‐sintered NASICON, NBO was demonstrated as a good liquid‐phase sintering additive for NASICON solid electrolyte. In the NASICON with 4.8 wt% NBO ceramic, most of the NASICON grains directly bonded with each other and some submicron sodium borates segregated in particulate form without full penetration to NASICON grain boundaries. This characteristic composite microstructure contributed to the high conductivity of the liquid‐phase sintered NASICON.     

Immobilization of alkaline phosphatase on magnetic particles by site-specific and covalent cross-linking catalyzed by microbial transglutaminase

Bacterial alkaline phosphatase (BAP) was site-specifically and covalently immobilized on magnetic particles (MPs) using the enzymatic reaction of microbial transglutaminase (MTG). Immobilization efficiency was affected by the chemical surface treatment of MPs and immobilized BAP exhibited more than 90% of the initial activity after 10 rounds of recycling.     

Criteria for versatile GaN MOVPE tool:high growth rate GaN by atmospheric pressure growth

Growth rate has a direct impact on the productivity of nitride LED production.Atmospheric pressure growth of GaN with a growth rate as high as 10μm/h and also Al_0.1Ga_0.9N growth of 1μm/h by using 4 inch by 11 production scale MOVPE are described.XRD of（002） and（102） direction was 200 arcsec and 250 arcsec, respectively.Impact of the growth rate on productivity is discussed.     

Oxygen release behavior of metastable tetragonal t′meta-(Ce0.5Zr0.5)2 phases prepared by reduction and successive oxidation of t′ phase

Tetragonal CaF₂-related-type t′-/Ce_0.5Zr_0.5)O₂ phase was reduced at 773 K ≤ T_red. ≤ 1073 K to prepare precursors with various oxygen compositions: Ce₂Zr₂O_712d /0.111 < δ < 0.379). Metastable tetragonal t^′_meta-(Ce_0.5Zr_0.5)O₂ phases were prepared by oxidizing in O₂ at 873 K the precursors, and subjected to evolved oxygen gas analysis by heating the samples at a constant rate. When the precursor was prepared at T_red: ? 773 K; i.e. δ ? 0:379; the oxygen release behavior of the tetragonal phase agreed approximately with that of the t^′. For δ < 0.29, distinct features of the t^′_meta-(Ce_0.5Zr_0.5)O₂ appeared in the XRD results and Raman spectra. The temperature exhibiting the maximum release rate of oxygen from the t^′_meta became lower with decreasing the d value. It could be concluded that the thermodynamic behavior of the t^′_meta is related closely to the precursor composition and becomes more unstable with decrease in the δ value. The t^′ and t^′_meta phases with disordered arrangement of Ce and Zr ions may belong to the same space group; nevertheless, difference in the random arrays of the Ce and Zr ions was suggested on the basis of the present experimental results.