3-D IIR filtering using decimated DFT-polyphase filter bank structures

Two three-dimensional (3-D) under-decimated uniform discrete Fourier transform polyphase filter bank structures are proposed along with two applications: first, the sub-pixel motion discrimination of two-dimensional spatial objects moving with approximately constant local velocity in a noisy 3-D spatio-temporal image sequence and, second, the selective filtering of 3-D spatio-temporal broad-band plane waves based on their directions of arrival. The desired 3-D filter passband shapes are realized utilizing combinations of highly selective first-order 3-D infinite-impulse response frequency-planar filters in each band between the analysis and synthesis sections. Measured spatio-temporal performance confirms the high-quality broad-band transmission of passband signals, high directional selectivity and low computational complexity.     

Adverse effects of vigabatrin in Angelman syndrome

New antiepileptic drugs designed for enhancing GABAergic inhibition, such as vigabatrin (VGB) may be effective in Angelman syndrome (AS), because associated convulsions could be related to a reduced GABA-receptor density or receptor abnormality. From our preliminary experiences in four children with AS treated with VGB, we conclude that it may induce and increase seizures in patients with AS.