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Wireless Personal Communications - The satellite network is one of the major source of information and these days small satellites are gaining lot of focus. The group of small satellites form a...  相似文献   
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This article describes current experimental models of status epilepticus (SE) and neuronal injury for use in the screening of new therapeutic agents. Epilepsy is a common neurological disorder characterized by recurrent unprovoked seizures. SE is an emergency condition associated with continuous seizures lasting more than 30 min. It causes significant mortality and morbidity. SE can cause devastating damage to the brain leading to cognitive impairment and increased risk of epilepsy. Benzodiazepines are the first-line drugs for the treatment of SE, however, many people exhibit partial or complete resistance due to a breakdown of GABA inhibition. Therefore, new drugs with neuroprotective effects against the SE-induced neuronal injury and degeneration are desirable. Animal models are used to study the pathophysiology of SE and for the discovery of newer anticonvulsants. In SE paradigms, seizures are induced in rodents by chemical agents or by electrical stimulation of brain structures. Electrical stimulation includes perforant path and self-sustaining stimulation models. Pharmacological models include kainic acid, pilocarpine, flurothyl, organophosphates and other convulsants that induce SE in rodents. Neuronal injury occurs within the initial SE episode, and animals exhibit cognitive dysfunction and spontaneous seizures several weeks after this precipitating event. Current SE models have potential applications but have some limitations. In general, the experimental SE model should be analogous to the human seizure state and it should share very similar neuropathological mechanisms. The pilocarpine and diisopropylfluorophosphate models are associated with prolonged, diazepam-insensitive seizures and neurodegeneration and therefore represent paradigms of refractory SE. Novel mechanism-based or clinically relevant models are essential to identify new therapies for SE and neuroprotective interventions.  相似文献   
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The area of non-noble metals based electro-catalysts with electrochemical activity and stability similar or superior to that of noble metal electro-catalyst for efficient hydrogen production from electrolytic and photoelectrochemical (PEC) water splitting is a subject of intense research. In the current study, exploiting theoretical first principles study involving determination of hydrogen binding energy to the surface of the electro-catalyst, we have identified the (Cu0.83Co0.17)3P: x at. % S system displaying excellent electrochemical activity for hydrogen evolution reaction (HER). Accordingly, we have experimentally synthesized (Cu0.83Co0.17)3P: x at. % S (x = 10, 20, 30) demonstrating excellent electrochemical activity with an onset overpotential for HER similar to Pt/C in acidic, neutral as well as basic media. The highest electrochemical activity is exhibited by (Cu0.83Co0.17)3P:30 at. % S nanoparticles (NPs) displaying overpotential to reach 100 mA cm?2 in acidic, neutral and basic media similar to Pt/C. The (Cu0.83Co0.17)3P:30 at. % S NPs also display excellent electrochemical stability in acidic media for long term electrolytic and PEC water splitting process [using our previously reported (Sn0.95Nb0.05) O2: N-600 nanotubes (NTs) as the photoanode]. The applied bias photon-to-current efficiency obtained using (Cu0.83Co0.17)3P:30 at. % S NPs as the cathode electro-catalyst for HER in an H-type PEC water splitting cell (~4%) is similar to that obtained using Pt/C (~4.1%) attesting to the promise of this exciting non-noble metal containing system.  相似文献   
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The Space today has considerable surge in distributed network of small satellites to meet the imperative demand of both commercial and scientific applications (Selva and Krejci in Acta Astronaut 74:50–68, 2012). As the complexity of the design and launch of large satellites is high , the need of distributed networking is gaining lot of interest in space domain as well. Thus single large satellite is replaced by many, small satellite that collaboratively work to perform the same functionality of single large satellite forming Space Based Wireless Sensor Network (SBWSN). The SBWSN are dynamically decoupled network as each satellite, orbits in its own path and the positioned with considerable distance between them. Stability of network with respect to formation flying to accomplish the task by collaboration is quite essential. In this paper, we develop the stability criteria in small satellite network using graph theory, covariant derivatives and linear algebra to ensure distributed processing and communication, required to accomplish the mission task.

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Earth abundant and economical rock salt (NaCl) particles of different sizes (<3 μm and 5–20 μm) prepared by high energy mechanical milling were used as water-soluble templates for generation of Si with novel nanoscale architectures via low pressure chemical vapor deposition (LPCVD). Si nanoflakes (SiNF) comprising largely amorphous Si (a-Si) with a small volume fraction of nanocrystalline Si (nc-Si), and Si nanorods (SiNR) composed of a larger volume fraction of crystalline Si (c-Si) and a small volume fraction of a-Si resulted from modification of the NaCl crystals. SiNF yielded first-cycle discharge and charge capacities of ~2,830 and 2,175 mAh·g?1, respectively, at a current rate of 50 mA·g?1 with a first-cycle irreversible loss (FIR loss) of ~15%–20%. SiNR displayed first-cycle discharge and charge capacities of ~2,980 and ~2,500 mAh·g?1, respectively, at a current rate of 50 mA·g?1 with an FIR loss of ~12%–15%. However, at a current rate of 1 A·g?1, SiNF exhibited a stable discharge capacity of ~810 mAh·g?1 at the end of 250 cycles with a fade rate of ~0.11% loss per cycle, while SiNR showed a stable specific discharge capacity of ~740 mAh·g?1 with a fade rate of ~0.23% loss per cycle. The morphology of the nanostructures and compositions of the different phases/phase of Si influence the performance of SiNF and SiNR, making them attractive anodes for lithium-ion batteries.
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Health care visualization through Internet of Things (IoT) over wireless sensor network (WSN) becomes a current research attention due to medical sensor evolution of devices. The digital technology-based communication system is widely used in all application. Internet of medical thing (IoMT) assisted healthcare application ensures the continuous health monitoring of a patient and provides the early awareness of the one who is suffered without human participation. These smart medical devices may consume with limited resources and also the data generated by these devices are large in size. These IoMT based applications suffer from the issues such as security, anonymity, privacy, and interoperability. To overcome these issues, data aggregation methods are the solution that can concatenate the data generated by the sensors and forward it into the base station through fog node with efficient encryption and decryption. This article proposed a well-organized data aggregation and secured transmission approach. The data generated by the sensor are collected and compressed. Aggregator nodes (AN) received the compressed data and concatenate it. The concatenated and encrypted data is forward to fog node using the enhanced Paillier cryptography-based encryption with Message Authentication code (MAC). Fog node extracts the forwarded data from AN using Fog message extractor method (FME) with decryption. The proposed system ensures data integrity, security and also protects from security threats. This proposed model is simulated in Network Simulator 2.35 and the evaluated simulation results proves that the aggregation with MAC code will ensures the security, privacy and also reduces the communication cost. Fog node usages in between Aggregator and base station, will reduce the cloud server/base station computational overhead and storage cost. The proposed ideology is compared with existing data aggregation schemes in terms of computational cost, storage cost, communication cost and energy cost. Cost of communication takes 18.7 ms which is much lesser than existing schemes.  相似文献   
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