刚果(金)某氧化铜钴矿絮凝沉降试验研究

对刚果(金)某氧化铜钴矿进行絮凝沉降试验研究。结果表明,原矿在磨矿粒度-0.150mm占80%、矿浆浓度10%～12%、絮凝剂用量5～10g/t,絮凝剂浓度0.05%～0.1%的条件下,沉降速度最高可达25m/h,底流浓度可达54%以上。对于磨矿粒度-0.150mm占80%、酸矿比132kg/t、初始矿浆浓度25%、常温浸出时间4h的浸出矿浆,在矿浆浓度6%、絮凝剂用量20g/t,絮凝剂浓度0.1%的条件下,沉降速度最高可达22m/h,底流浓度可达47%以上。     

Lead Zirconate Titanate Film Formation Technology with Use of Spray Coating Method

This paper presents a three-dimensional microfabrication and integration technology for MEMS smart materials that utilizes a spray coating method. Spray coating is shown to be most effective for additional deposition on non-planar surfaces. PZT films were formed both on flat and uneven surfaces at a thickness of about 1μ m. Perovskite structures were formed with suitable heat treatment and ferroelectric P-E hysteresis loop was also obtained. This paper is the first report from our group and other researchers on the deposition of smart materials for MEMS using a spray coating method. Spray coating has been proposed as an effective three-dimensional coating method which can be used to deposit piezoelectrics, pyroelectrics, magnetics, etc. for sensors and actuators. The hydrophilic and hydrophobic properties between the substrate surface and ejected liquid are most essential process factors in the spray coating method for improving the film growth conditions.     

Chaperone-mediated autophagy targeting chimeras (CMATAC) for the degradation of ERα in breast cancer

Estrogen receptor alpha (ERα/ESR1) is overexpressed in over half of all breast cancers and is considered a valuable therapeutic target in ERα positive breast cancer. Here, we designed a membrane-permeant Chaperonemediated Autophagy Targeting Chimeras (CMATAC) peptide to knockdown endogenous ERα protein through chaperone-mediated autophagy. The peptide contains a cell membrane-penetrating peptide (TAT) that allows the peptide to by-pass the plasma membrane, an αI peptide as a protein-binding peptide (PBD) that binds specifically to ERα, and CMA-targeting peptide (CTM) that targeting chaperone-mediated autophagy. We validated that ERα targeting peptide was able to target and degrade ERα to reduce the viability of ERα positive breast cancer cells. Taken together, our studies provided a new method to reduce the level of intracellular ERα protein via CMATAC, and thus may provide a new strategy for the treatment of ERα positive breast cancer.     

含分布式电源配电网中重合器的优化配置

基于配电网的可靠性指标和评估方法,分析了分布式电源接入后对配电网可靠性的影响。在考虑提高系统和用户侧的供电可靠性的基础上,分析了配电系统引入分布式发电对重合器等保护设备配合的影响,选择了配电网重合器位置优化配置的数学模型。结合用户停电感受,利用遗传算法给出该模型求解算法,通过算例验证了该种算法的有效性。     

蒙特卡罗法在调制解调中的应用

在加性高斯噪声干扰条件下的2FSK和16QAM调制解调方法基础上,根据蒙特卡罗仿真方法基本思想,建立在加性噪声干扰下的相关检测系统蒙特卡罗仿真模型。模型通过Matlab软件方法实现,最终仿真结果与对应系统的理论误码率基本符合。