破片式战斗部优化设计技术研究

侧重研究了破片式战斗部装药外形的优化设计技术。提出了装药外形与破片飞散特性（如破片飞散角，分布带宽等）之间的数学描述；建立了圆弧和对数螺线装药外形母线与战斗部其他设计参数间的数学模型。在假定约束条件下，优化设计了破片了聚焦式战斗部的结构参数；静爆试验结果表明，破片分布与理论计算吻合较好。     

基于降雨资料的雨量预警指标阈值求解模型

为保证雨量预警指标阈值在有效周期范围内发挥预警作用,通过分析现有雨量预警指标阈值的确定方法,提出了基于区域临界雨量法-降雨灾害同频率法-R/S分析法的雨量预警指标阈值求解模型。将该模型应用于江苏省泰兴市降雨时间序列的分析,对最大日降水量时间序列进行阈值确定、趋势分析,并用指标阈值进行预警验证。结果表明,该模型的雨量预警指标阈值确定结果相较单一模型更为准确,且具有一定的时效性,可为农村基层防汛预报预警提供参考。     

Local Epidermal Endocrine Estrogen Protects Human Melanocytes against Oxidative Stress,a Novel Insight into Vitiligo Pathology

As the outermost barrier of the body, skin is a major target of oxidative stress. In the brain, estrogen has been reported synthesized locally and protects neurons from oxidative stress. Here, we explored whether estrogen is also locally synthesized in the skin to protect from oxidative stress and whether aberrant local estrogen synthesis is involved in skin disorders. Enzymes and estrogen receptor expression in skin cells were examined first by quantitative real-time PCR and Western blot analyses. Interestingly, the estrogen synthesis enzyme was mainly localized in epidermal keratinocytes and estrogen receptors were mainly expressed in melanocytes among 13 kinds of cultured human skin cells. The most abundant estrogen synthesis enzyme expressed in the epidermis was 17β-hydroxysteroid dehydrogenase 1 (HSD17β1) localized in keratinocytes, and the most dominant estrogen receptor expressed in the epidermis was G protein-coupled estrogen receptor 1 (GPER1) in melanocytes. To investigate whether keratinocyte-derived estradiol could protect melanocytes from oxidative stress, cultured human primary epidermal melanocytes (HEMn-MPs) were treated with H₂O₂ in the presence or absence of 17β estradiol or co-cultured with HSD17β1 siRNA-transfected keratinocytes. Keratinocyte-derived estradiol exhibited protective effects against H₂O₂-induced cell death. Further, reduced expression of HSD17β1 in the epidermis of skin from vitiligo patients was observed compared to the skin from healthy donors or in the normal portions of the skin in vitiligo patients. Our results suggest a possible new target for interventions that may be used in combination with current therapies for patients with vitiligo.     

论经济新常态下水利水电工程建设管理之完善

在经济新常态背景下,从节约国家资源、降低成本、提高质量效率、保护生态环境、最大限度发挥水利水电工程作用出发,水利水电工程建设与管理工作也应适应新常态。水利水电事业的发展应告别过去传统粗放的高速增长模式,放稳速度,抓质量,重效益,求精细,保持科学合理的可持续稳定增长。对新常态下如何完善水利水电工程建设与管理展开了探讨,旨在解决当前水利水电工程建设与管理中存在的问题,促进水利水电事业的科学发展。     

Mixed graph convolution and residual transformation network for skeleton-based action recognition

Action recognition based on a human skeleton is an extremely challenging research problem. The temporal information contained in the human skeleton is more difficult to extract than the spatial information. Many researchers focus on graph convolution networks and apply them to action recognition. In this study, an action recognition method based on a two-stream network called RNXt-GCN is proposed on the basis of the Spatial-Temporal Graph Convolutional Network (ST-GCN). The human skeleton is converted first into a spatial-temporal graph and a SkeleMotion image which are input into ST-GCN and ResNeXt, respectively, for performing the spatial-temporal convolution. The convolved features are then fused. The proposed method models the temporal information in action from the amplitude and direction of the action and addresses the shortcomings of isolated temporal information in the ST-GCN. The experiments are comprehensively performed on the four datasets: 1) UTD-MHAD, 2) Northwestern-UCLA, 3) NTU RGB-D 60, and 4) NTU RGB-D 120. The proposed model shows very competitive results compared with other models in our experiments. On the experiments of NTU RGB?+?D 120 dataset, our proposed model outperforms those of the state-of-the-art two-stream models.

     

Frequency multiplexed superconducting quantum interference device readout of large bolometer arrays for cosmic microwave background measurements

A technological milestone for experiments employing transition edge sensor bolometers operating at sub-Kelvin temperature is the deployment of detector arrays with 100s-1000s of bolometers. One key technology for such arrays is readout multiplexing: the ability to read out many sensors simultaneously on the same set of wires. This paper describes a frequency-domain multiplexed readout system which has been developed for and deployed on the APEX-SZ and South Pole Telescope millimeter wavelength receivers. In this system, the detector array is divided into modules of seven detectors, and each bolometer within the module is biased with a unique ～MHz sinusoidal carrier such that the individual bolometer signals are well separated in frequency space. The currents from all bolometers in a module are summed together and pre-amplified with superconducting quantum interference devices operating at 4 K. Room temperature electronics demodulate the carriers to recover the bolometer signals, which are digitized separately and stored to disk. This readout system contributes little noise relative to the detectors themselves, is remarkably insensitive to unwanted microphonic excitations, and provides a technology pathway to multiplexing larger numbers of sensors.     

Oxidation kinetics and high temperature in-situ observation of the oxidation behaviour of NbSi_2 at 1023 K

Pest oxidation has been known for a long time in refractory transition-metal disilicides such as NbSi2 and MoSi2[1―4]. However, the origin of pesting reaction of these materials is still under debate. Although the pesting phenomenon in NbSi2 has been reported in several works[5―7], a direct study of the mechanism is scarce at the moment. Compared to NbSi2, pesting in MoSi2 has received relatively extensive attention. Mckamey et al.[8] showed fragmentation near 773K occurred easily in as…     

Component analysis and risk assessment of biogas slurry from biogas plants

Massive amounts of biogas slurry are produced due to the development of biogas plants. The pollution features and the risk of biogas slurry were fully evaluated in this work. Thirty-one biogas slurry samples were collected from sixteen different cities and five different raw materials biogas plants (e.g. cattle manure, swine manure, straw-manure mixture, kitchen waste and chicken manure). The chemical oxygen demand (COD), ammonia nitrogen (NH₄⁺ - N), anions (e.g. Cl^-,SO₄^2-, NO₃^- and PO₄^-3), antibiotics (e.g. sulphonamides, quinolones, β₂-receptor agonists, macrolides, tetracyclines and crystal violet) and heavy metals (e.g. Cu, Cd, As, Cr, Hg, Zn and Pb) contents from these biogas slurry samples were systematically investigated. On this basis, risk assessment of biogas slurry was also performed. The concentrations of COD, NH₄⁺ and PO₄^-3 in biogas slurry samples with chicken manure as raw material were significantly higher than those of other raw materials. Therefore, the biogas slurry from chicken manure raw material demonstrated the most serious eutrophication threat. The antibiotic contents in biogas slurry samples from swine manure were the highest among five raw materials, mostly sulphonamides, quinolones and tetracyclines. Biogas slurry revealed particularly serious arsenic contamination and moderate potential ecological risk. The quadratic polynomial stepwise regression model can quantitatively describe the correlation among NH₄⁺ - N, PO₄^-3 and heavy metals concentration of biogas slurry. This work demonstrated a universal potential threat from biogas slurry that can provide supporting data and theoretical basis for harmless treatment and reuse of biogas slurry.     

基于农耕文化的川西林盘导视系统设计研究

目的 以导视系统为载体赋予川西林盘农耕文化新意境,是展现农耕文化的一种有效形式。以成都市郫都区林盘农耕文化导视系统设计为模型,以乡村发展复兴为契机推进农耕文化与乡村产业革新相融合,打造突显川西林盘特色的导视系统。方法 结合设计符号学理论,从元素符号的语义、语用、语境、语构四个维度,剖析川西林盘导视系统设计方法,以造型元素、色彩、材质肌理等客体对象解构导视系统符号化体系;同时与“境-景-人-物”四维体系相结合构建川西林盘导视系统。结果 表达林盘农耕文化外延造型及内涵意识,借助导视系统唤起川西农耕文化审美范式记忆,建立具有农耕文化特征符号的导视系统设计方法。结论 保护与传承川西农耕文化特色,提升川西林盘整体文化形象,拓展现代乡村导视系统设计思路。     

猪粪原料沼气工程系统中的原核微生物群落结构

采集了中国不同地区的13个猪粪原料沼气工程系统的沼液,利用16S rRNA基因扩增子高通量测序技术研究了原核微生物群落组成及多样性。结果表明,Firmicutes是猪粪原料沼气工程系统中的主导微生物,其次为Bacteroidetes、Proteobacteria和Chloroflexi。在相似的温度条件下,铵态氮与磷酸盐的比例是影响猪粪原料沼气工程系统原核微生物群落结构及多样性的主要因素。较高的铵磷比会富集Firmicutes门的菌群,尤其是Clostridium sensu stricto属;而较低的铵磷比则有利于Bacteroidetes和Proteobacteria。不同营养类型产甲烷菌对高浓度铵态氮耐受程度不同（氢营养型产甲烷菌 >Methanosarcina >Methanosaeta）,影响着产甲烷菌群落组成。产甲烷菌和互营菌的群落组成是影响沼气发酵产气效率的重要生物因素,高比例的氢型产甲烷菌和丙酸互营菌更有利于提高产甲烷效率。