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1.
Converting unconstrained video sequences into videos that loop seamlessly is an extremely challenging problem. In this work, we take the first steps towards automating this process by focusing on an important subclass of videos containing a single dominant foreground object. Our technique makes two novel contributions over previous work: first, we propose a correspondence‐based similarity metric to automatically identify a good transition point in the video where the appearance and dynamics of the foreground are most consistent. Second, we develop a technique that aligns both the foreground and background about this transition point using a combination of global camera path planning and patch‐based video morphing. We demonstrate that this allows us to create natural, compelling, loopy videos from a wide range of videos collected from the internet. 相似文献
2.
When the purpose of a survival regression model is to predict future outcomes, the predictive accuracy of the model needs to be evaluated before practical application. Various measures of predictive accuracy have been proposed for survival data, none of which has been adopted as a standard, and their inclusion in statistical software is disregarded. We developed the surev library for R and S-PLUS, which includes functions for evaluating the predictive accuracy measures proposed by Schemper and Henderson. The library evaluates the predictive accuracy of parametric regression models and of Cox models. The predictive accuracy of the Cox model can be obtained also when time-dependent covariates are included because of non-proportional hazards or when using Bayesian model averaging. The use of the library is illustrated with examples based on a real data set. 相似文献
3.
Laura Mannarino Lara Paracchini Federica Pezzuto Gheorghe Emilian Olteanu Laura Moracci Luca Vedovelli Irene De Simone Cristina Bosetti Monica Lupi Rosy Amodeo Alessia Inglesi Maurizio Callari Serena Penpa Roberta Libener Sara Delfanti Antonina De Angelis Alberto Muzio Paolo Andrea Zucali Paola Allavena Giovanni Luca Ceresoli Sergio Marchini Fiorella Calabrese Maurizio DIncalci Federica Grosso 《International journal of molecular sciences》2022,23(10)
4.
Laura Micheli Lara Testai Andrea Angeli Donatello Carrino Alessandra Pacini Francesco Margiotta Lorenzo Flori Claudiu T. Supuran Vincenzo Calderone Carla Ghelardini Lorenzo Di Cesare Mannelli 《International journal of molecular sciences》2022,23(11)
Neuropathy development is a major dose-limiting side effect of anticancer treatments that significantly reduces patient’s quality of life. The inadequate pharmacological approaches for neuropathic pain management warrant the identification of novel therapeutic targets. Mitochondrial dysfunctions that lead to reactive oxygen species (ROS) increase, cytosolic Ca2+ imbalance, and lactate acidosis are implicated in neuropathic pain pathogenesis. It has been observed that in these deregulations, a pivotal role is played by the mitochondrial carbonic anhydrases (CA) VA and VB isoforms. Hence, preclinical studies should be conducted to assess the efficacy of two novel selenides bearing benzenesulfonamide moieties, named 5b and 5d, and able to inhibit CA VA and VB against paclitaxel-induced neurotoxicity in mice. Acute treatment with 5b and 5d (30–100 mg/kg, per os – p.o.) determined a dose-dependent and long-lasting anti-hyperalgesic effect in the Cold plate test. Further, repeated daily treatment for 15 days with 100 mg/kg of both compounds (starting the first day of paclitaxel injection) significantly prevented neuropathic pain development without the onset of tolerance to the anti-hyperalgesic effect. In both experiments, acetazolamide (AAZ, 100 mg/kg, p.o.) used as the reference drug was partially active. Moreover, ex vivo analysis demonstrated the efficacy of 5b and 5d repeated treatments in reducing the maladaptive plasticity that occurs to glia cells in the lumbar portion of the spinal cord and in improving mitochondrial functions in the brain and spinal cord that were strongly impaired by paclitaxel-repeated treatment. In this regard, 5b and 5d ameliorated the metabolic activity, as observed by the increase in citrate synthase activity, and preserved an optimal mitochondrial membrane potential (ΔΨ) value, which appeared depolarized in brains from paclitaxel-treated animals. In conclusion, 5b and 5d have therapeutic and protective effects against paclitaxel-induced neuropathy without tolerance development. Moreover, 5b and 5d reduced glial cell activation and mitochondrial dysfunction in the central nervous system, being a promising candidate for the management of neuropathic pain and neurotoxicity evoked by chemotherapeutic drugs. 相似文献
5.
Søren Lindbæk Broman Samuel Lara‐Avila Christine Lindbjerg Thisted Andrew D. Bond Sergey Kubatkin Andrey Danilov Mogens Brøndsted Nielsen 《Advanced functional materials》2012,22(20):4249-4258
Molecular switches play a central role for the development of molecular electronics. In this work it is demonstrated that the reproducibility and robustness of a single‐molecule dihydroazulene (DHA)/vinylheptafulvene (VHF) switch can be remarkably enhanced if the switching kernel is weakly coupled to electrodes so that the electron transport goes by sequential tunneling. To assure weak coupling, the DHA switching kernel is modified by incorporating p‐MeSC6H4 end‐groups. Molecules are prepared by Suzuki cross‐couplings on suitable halogenated derivatives of DHA. The synthesis presents an expansion of our previously reported bromination–elimination–cross‐coupling protocol for functionalization of the DHA core. For all new derivatives the kinetics of DHA/VHF transition has been thoroughly studied in solution. The kinetics reveals the effect of sulfur end‐groups on the thermal ring‐closure of VHF. One derivative, incorporating a p‐MeSC6H4 anchoring group in one end, has been placed in a silver nanogap. Conductance measurements justify that transport through both DHA (high resistivity) and VHF (low resistivity) forms goes by sequential tunneling. The switching is fairly reversible and reenterable; after more than 20 “ON‐OFF” switchings, both DHA and VHF forms are still recognizable, albeit noticeably different from the original states. 相似文献
6.
Hanying Li Huolin L. Xin Miki E. Kunitake Ellen C. Keene David A. Muller Lara A. Estroff 《Advanced functional materials》2011,21(11):2028-2034
Biogenic single‐crystal composites, such as sea urchin spines and calcitic prisms from mollusk shells, contain organic macromolecules inside of inorganic single‐crystal matrices. The nanoscale internal structure of these materials, however, is poorly understood, especially how the biomacromolecules are distributed within the crystals without significantly disrupting the crystalline lattice. Here, annular dark‐field scanning transmission electron microscopy and electron tomography reveal, in three dimensions, how biomacromolecules are distributed within the calcitic prisms from Atrina rigida shells. Disk‐like nanopatches, whose scattering intensity is consistent with organic inclusions, are observed to be anisotropically arranged within a continuous, single‐crystalline calcite matrix. These nanopatches are preferentially aligned with the (000l) planes of calcite. Along the crystallographic c‐axis, there are alternating organic‐rich and ‐poor regions on a length scale of tens of nanometers, while, in the ab plane, the distribution of nanopatches is more random and uniform. The structural features elucidated in this work have relevance to understanding the structure–property relationships and formation mechanisms of biominerals, as well as to the development of bio‐inspired strategies to extrinsically tune the properties of single‐crystals. 相似文献
7.
Moosvi S.M.A. McLernon D.C. Orozco-Lugo A.G. Lara M.M. Ghogho M. 《Communications Letters, IEEE》2008,12(3):179-181
In this letter we propose, for the first time, a solution to the problem of carrier frequency offset (CFO) estimation within the data dependent superimposed training (DDST) framework for channel estimation. While time division multiplexed (TDM) trained systems can use the TDM sequence to determine the CFO, the original attraction of DDST for channel estimation was that it avoided any TDM training. So in this letter we show how CFO estimation can still be very effectively performed with the DDST algorithm, while continuing to preclude the need for any additional bandwidth-consuming TDM training. Finally, simulations are presented that verify the theoretical results. 相似文献
8.
9.
Paulo S. André António L. Teixeira Armando N. Pinto Lara P. Pellegrino Berta B. Neto José F. Rocha Joäo L. Pinto Paulo N. Monteiro 《ETRI Journal》2006,28(2):257-259
In this letter, we will evaluate the performance degradation of a 40 km high‐speed (40 Gb/s) optical system, induced by optical fiber variations of the chromatic dispersion induced by temperature changes. The chromatic dispersion temperature sensitivity will be estimated based on the signal quality parameters. 相似文献
10.
Developing Smart Grids Based on GPRS and ZigBee Technologies Using Queueing Modeling–Based Optimization Algorithm 下载免费PDF全文
Gustavo Batista de Castro Souza Flávio Henrique Teles Vieira Cláudio Ribeiro Lima Getúlio Antero de Júnior Deus Marcelo Stehling de Castro Sérgio Granato de Araujo Thiago Lara Vasques 《ETRI Journal》2016,38(1):41-51
Smart metering systems have become widespread around the world. RF mesh communication systems have contributed to the creation of smarter and more reliable power systems. This paper presents an algorithm for positioning GPRS concentrators to attain delay constraints for a ZigBee‐based mesh network. The proposed algorithm determines the number and placement of concentrators using integer linear programming and a queueing model for the given mesh network. The solutions given by the proposed algorithm are validated by verifying the communication network performance through simulations. 相似文献