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1.
Analysis of electrocardiograms during atrial fibrillation 总被引:1,自引:0,他引:1
Vincent Jacquemet Adriaan van Oosterom Jean-Marc Vesin Lukas Kappenberger 《IEEE engineering in medicine and biology magazine》2006,25(6):79-88
The research discussed in this article is motivated by the search for an optimal classification of the different types of atrial fibrillation (AF) on the basis of recorded atrial signals. This would facilitate the selection of an optimal therapy. This article focuses on the biophysical models of the genesis of ECG waveforms during AF. The model of the electric activity of the atria was found to have sufficient realism to be used to describe the electric sources during AF. The inclusion of the volume conduction model resulted in electrocardiographic signals that are in all aspects similar to those observed clinically. The model is currently applied to solve various problems related to optimal signal preprocessing and extraction of features in AF signals for the classification of AF abnormalities. The biophysical model of the atrial activity is an essential element in this research, since it is capable of describing the electric source specifications derived from different hypotheses relating to the etiology of AF 相似文献
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The B-C-Ti system has been critically assessed and calculated in the temperature region of 1400 °C up to the melting range
employing the Thermocalc program system. The liquid phase is described using a substitutional model. The ternary solid solubility
of boron in titanium carbide has been taken into account by using a two-sublattice model (Ti)1(B,C,Va),. The calculated isotherms and isopleths are presented and compared with the experimental information. The B-C-Ti
reaction scheme is presented including the Ti3B4 phase. 相似文献
5.
Wolfgang Tillmann Matthias Manka Lukas Wojarski Michael Holewa 《Science & Technology of Welding & Joining》2020,25(4):290-296
ABSTRACTTools for machining are exposed to high loads, wear, and elevated temperatures. Commonly, such tools consist of cemented carbides and tool steel. To combine the advantages of both materials, high-quality-joints with high strengths are desired. When brazing these materials, the main challenge is the mismatch of the Coefficient of Thermal Expansion (CTE) and the poor wettability of cemented carbides by molten filler alloys. In this regard, the feasibility of two custom-made alloys (CuNi12Si5, CuNi12Si5B0.4) was analysed. Besides being a cost-efficient alternative, these alloys offer the possibility to modify their mechanical properties by precipitation hardening to reduce stresses within the final joints. Thus, this paper shows that a temperature of 1060°C is suitable for wetting and brazing tests on different substrates. 相似文献
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Zdenek Vasicek Michal Bidlo Lukas Sekanina 《Soft Computing - A Fusion of Foundations, Methodologies and Applications》2013,17(11):2163-2180
Image processing represents a research field in which high-quality solutions have been obtained using various soft computing techniques. Evolutionary algorithms constitute a class of stochastic search methods that are applicable in both optimization and design tasks. In the area of circuit design Cartesian Genetic Programming has often been utilized in combination with an algorithm of Evolutionary Strategy. Digital image filters represent a specific class of circuits whose design can be performed by means of this approach. Switching filters are advanced non-linear filtering techniques in which the main idea is to detect and filter the noise pixels while keeping the uncorrupted pixels unchanged in order to increase the quality of the resulting image. The aim of this article is to present a robust design technique based on Cartesian Genetic Programming for the automatic synthesis of switching image filters intended for real-time processing applications. The robustness of the proposed evolutionary approach is evaluated using four design problems including the removal of salt and pepper noise, random shot noise, impulse burst noise and impulse burst noise combined with random shot noise. An extensive evaluation is performed in order to compare the properties of the evolved switching filters with the best conventional solutions. The evaluation has shown that the evolved switching filters exhibit a very good trade off between the quality of filtering and the implementation cost in field programmable gate arrays. 相似文献
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Monuko du Plessis Herzl Aharoni Lukas W. Snyman 《Sensors and actuators. A, Physical》2000,80(3):242-248
A novel multi-terminal silicon light emitting device (TRANSLED) is described where both the light intensity and spatial light pattern of the device are controlled by an insulated MOS gate voltage. This presents a major advantage over two terminals Si-LEDs, which require direct modulation of the relatively high avalanche current. It is found that, depending on the bias conditions, the light intensity is either a linear or a quadratic function of the applied gate voltage. The nonlinear relationship facilitates new applications such as the mixing of electrical input signals and modulating the optical output signal, which cannot readily be achieved with two terminal Si-LEDs, since they exhibit a linear relationship between diode avalanche current and light intensity. Furthermore, the control gate voltage can also modulate the emission pattern of the light emitting regions, for example, changing the TRANSLED from an optical line source to two point sources. 相似文献
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Ivanina Mutisheva Steve Robatel Lukas Briswyl Mirjam Schenk 《International journal of molecular sciences》2022,23(18)
Although single-cell RNA sequencing (scRNA-seq) is currently the gold standard for the analysis of cell-specific expression profiles, the options for processing, staining, and preserving fresh cells remain very limited. Immediate and correct tissue processing is a critical determinant of scRNA-seq success. One major limitation is the restricted compatibility of fixation approaches, which must not destabilize or alter antibody labeling or RNA content or interfere with cell integrity. An additional limitation is the availability of expensive, high-demand cell-sorting equipment to exclude debris and dead or unwanted cells before proceeding with sample sequencing. The goal of this study was to develop a method that allows cells to be fixed and stored prior to FACS sorting for scRNA-seq without compromising the quality of the results. Finally, the challenge of preserving as many living cells as possible during tissue processing is another crucial issue addressed in this study. Our study focused on pancreatic ductal adenocarcinoma samples, where the number of live cells is rather limited, as in many other tumor tissues. Harsh tissue dissociation methods and sample preparation for analysis can negatively affect cell viability. Using the murine pancreatic cancer model Pan02, we evaluated the semi-automated mechanical/enzymatic digestion of solid tumors by gentleMACS Dissociator and compared it with mechanical dissociation of the same tissue. Moreover, we investigated a type of cell fixation that is successful in preserving cell RNA integrity yet compatible with FACS and subsequent scRNA-sequencing. Our protocol allows tissue to be dissociated and stained in one day and proceeds to cell sorting and scRNA-seq later, which is a great advantage for processing clinical patient material. 相似文献
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文章介绍了南京"德中同行"大型文化科技展览活动的规划,特别是生态竹子展馆的设计,以及竹制建筑的构造细部等技术解决方案. 相似文献